This was achieved by (1) developing a system which applies quantum cryptographic communications technology to clinical sequencing, and (2) using that system to safely transmit cancer genome analysis data (exome sequence (Note 1) data), via online expert panel attended by physicians and other experts to analyze the sequenced data. This is the world's first development and demonstration of a system using quantum cryptographic communication technology in the field of genomic medicine.
Clinical sequencing is a new examination in genomic medicine that uses a next-generation sequencer to read a patient's gene sequence at ultra-high speed. The results of the genomic data analysis are then provided to physicians and other experts to assist in patient diagnosis and treatment selection. This system builds on and extends capabilities that Toshiba and ToMMo announced in January of this year, and the achievements of this demonstration are a major step toward a practical system that will provide safe and secure genomic medicine.
This research was carried out as part of the Strategic Innovation Creation Program (SIP) of the
Details
In January this year, Toshiba and ToMMo announced on a series of experiments of quantum cryptography transmission that took place in July and
Clinical sequencing covers genome analysis data which is highly confidential personal information closely related to one's health and physical condition that must be kept secure. For the same reason, support is also needed for the data generated by online expert panel attended by physicians and experts who share patient's genetic data and diagnostic results via remote access.
After considering this, Toshiba, ToMMo and
Real-time transmission of genome analysis data (exome sequencing data)
Data transmission for an online expert panel, including analyzing results over conference audio and visual feeds.
Implementation of A: Transmission of genome analysis data uses a one-time pad (Note cryptography that Toshiba and ToMMo announced in
Genome data is encrypted as it is sequenced, with a cryptographic key distributed from the quantum key distribution system, and transmitted using the one-time pad. The transmission system is designed for ease of use. Menus on the operator's screen allow simple selection of the number of the specimen for analysis, and of the transmission method.
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