Achaogen, Inc. appointed Blake Wise as the Chief Executive Officer of the Company, effective January 1, 2018. Mr. Wise will replace Kenneth J. Hillan, M.B., Ch.B., whom the Board appointed President, R&D and President of the company, effective January 1, 2018. Mr. Wise currently serves as the Company's President and Chief Operating Officer.

The Board also appointed Mr. Wise as a member of the Board, effective January 1, 2018. Mr. Wise was appointed as a Class III director, with an initial term expiring at the Company's annual meeting of stockholders to be held in 2020. Dr. Hillan will remain a member of the Board.

In connection with Mr. Wise's appointment to the Board, the Board also increased the size of the Board from nine directors to ten directors, effective January 1, 2018. Mr. Wise has served as the Company's President and Chief Operating Officer since February 2017 and served as the Company's Chief Operating Officer from October 2015 to February 2017. From 2002 to August 2015, Mr. Wise served in roles of increasing responsibility at Genentech, including serving as Vice President, Cross BioOncology; Senior Director, Franchise Head and Life Cycle Leader, Lytics; Sales Director, BioOncology, Avastin; Marketing Director, Immunology and Cystic Fibrosis; and Director, Interactive Marketing.

Dr. Hillan has served on the Board since October 2011. Dr. Hillan served as the Company's Chief Medical Officer from April 2011 until July 2014, served as the Company's President from October 2011 to February 2017 and has served as the Company's Chief Executive Officer since October 2011. Prior to joining Achaogen, from 1994 to April 2011, Dr. Hillan served at Genentech.

Dr. Hillan was responsible for numerous successful drug approvals and led the medical and scientific strategies for Genentech's Immunology, Tissue Growth and Repair drug portfolio. For Genentech, he served in a number of key leadership positions in research and development, including Senior Vice President Clinical Development, Inflammation, Vice President Immunology, Tissue Growth and Repair, Vice President Development Sciences and Vice President Research Operations and Pathology. Dr. Hillan also previously served as Senior Vice President and head of Clinical Development and Product Development Strategy in Asia-Pacific for F. Hoffmann-La Roche AG in Shanghai, China.

Dr. Hillan served on the board of directors of Relypsa, Inc. from June 2014 to September 2016 when it merged with Galenica AG.