On October 7, 2021, Fabian Tenenbaum, the Chief Executive Officer of Bellerophon Therapeutics, Inc. notified the Company’s Board of Directors that he will resign as Chief Executive Officer and as a director of the Company and its subsidiaries, effective October 24, 2021, to pursue other opportunities. Mr. Tenenbaum’s decision to resign is not due to any disagreement with the Company on any matters relating to the Company’s operations, policies, or practices. The Company plans to engage in a search to identify a successor to Mr. Tenenbaum.