On August 9, 2019, Alan Lins notified Plus Therapeutics, Inc. (the Company) of his intention to resign from his position as Vice President of Finance and Controller. His resignation as Vice President of Finance and Controller will be effective immediately. Mr. Lins' departure as Vice President of Finance and Controller is not due to a dispute or disagreement with the Company or the Company's auditors.

On August 9, 2019, the board of directors of the Company appointed Marc H. Hedrick, M.D., the Company's President and Chief Executive Officer, to serve as the Company's principal executive, financial and accounting officer effective immediately.