On February 18, 2022, the Board of Directors of Sigilon Therapeutics, Inc. appointed Josias Fantato De Pontes as the Company's Acting Chief Financial Officer. Upon his appointment, Mr. Pontes replaced Dr. Rogerio Vivaldi, M.D., as the Company's principal financial officer. Mr. Pontes will continue to serve as the Company's principal accounting officer.

Mr. Pontes, age 55, previously served as the Company's Vice President, Head of Finance since November 2019. Prior to joining the Company, Mr. Pontes was Senior Director, Financial Planning and Analysis at Zafgen, Inc., from December 2017 to August 2019.