Almirall S A : and Paratek enter into a License Agreement for Seysara® in China

Almirall, S.A. (ALM) has today announced that Seysara® (sarecycline), an innovative first in class tetracycline-derived oral antibiotic for the treatment of inflammatory lesions of moderate to severe nonnodular acne vulgaris, is expected to be submitted to NMDA in 2023. Almirall has the commercialization rights for the medicine in the US, and will develop it for acne in China under a License Agreement from Paratek Pharmaceuticals, Inc. (Nasdaq: PRTK).

Under the terms of the agreement entered into between Almirall and Paratek, Almirall will be responsible for development, registration and commercialization of the product in China in exchange for royalties calculated as a percentage of net sales once the product is launched onto the market.

Seysara® represents the first dermatology product for Almirall to entry and for building the company's strategic dermatology portfolio in China.

'At Almirall we are convinced that the launch of Seysara® in China will be a big step forward for many patients with acne in the country. Moderate to severe acne is a widespread issue in China, and Seysara® will bring a new and innovative solution to these patients', Peter Guenter, CEO, Almirall, added.

Seysara® is an oral tablet taken once daily with or without food. It has shown significant reduction of inflammatory lesions as early as three weeks after the start of treatment and is generally safe and well tolerated. Seysara® is an innovative treatment for patients with moderate to severe acne.

The Food and Drug Administration (FDA) approved Seysara® in October 2018. In order to prove the efficiency and safety of the medicine in China, Almirall will conduct a Phase III and PK study among Chinese population starting in 2020.

About Almirall

Almirall is a leading skin-health focused global pharmaceutical company that partners with healthcare professionals, applying science to provide medical solutions to patients and future generations. Our efforts are focused on fighting skin health diseases and helping people feel better. We support healthcare professionals in their continuous improvements, providing our innovative solutions where they are needed.

The company was founded almost 75 years ago and has its headquarters in Barcelona. It is listed on the Spanish Stock Exchange (ticker: ALM). Almirall has become a key source of value creation for society thanks to its commitment to its principal shareholders and its decision to help others by understanding their challenges and using science to provide solutions for real life. Total Revenues in 2019 were 811 million euros. Almirall has c. 1,800.

For more information see www.almirall.com

About Seysara®

Seysara® (sarecycline) is a once-daily, oral tetracycline-derived antibiotic with anti-inflammatory properties for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients 9 years of age and older. Seysara® has proven to be a safe and effective treatment in two 12-week multicenter, randomized, double-blind, placebo-controlled studies (Study 1 [NCT02320149] and Study 2 [NCT02322866]). Efficacy was assessed in a total of 2002 subjects 9 years of age and older.