BioInvent International : partner Oxurion announces full enrollment of its Phase 2 trial evaluating the combination of anti-PlGF (THR-317) and anti-VEGF (ranibizumab) for the treatment of DME, ahead of schedule

Lund, Sweden - April 4, 2019 - BioInvent International AB's (publ) (BINV) partner Oxurion NV announced today that all patients have been enrolled in its Phase 2 trial evaluating efficacy and safety of its THR-317, a humanized antibody against placental growth factor (PlGF), in combination with anti-VEGF (ranibizumab), an anti-vascular endothelial growth factor (VEGF) antibody, for the treatment of Diabetic Macular Edema (DME). A total of 70 patients were enrolled in the study, ahead of schedule. Topline data from the study are expected by Q3 2019.

In 2017, Oxurion gained full and exclusive ownership of THR-317 for development and commercialization in all non-oncology indications. In exchange, BioInvent is entitled to five percent of the program's economic value.

For further information, see Oxurion's press release of April 4, 2019 (www.oxurion.com).

About BioInvent
BioInvent International AB (OMXS: BINV) is focused on the discovery and development of novel and first-in-class immuno-modulatory antibodies to treat cancer. The Company's lead program BI-1206, is currently in Phase l/ll for non-Hodgkin lymphoma and chronic lymphatic leukemia. BioInvent's pre-clinical portfolio is focused on targeting key immune suppressive cells and pathways of the tumor microenvironment, including regulatory T cells, tumor-associated myeloid cells and mechanisms of antibody drug-resistance. The Company has a strategic research collaboration with Pfizer Inc., and partnerships with Transgene, Bayer Pharma, Daiichi Sankyo, and Mitsubishi Tanabe Pharma. BioInvent generates near term revenues from its fully integrated manufacturing unit producing antibodies for third parties for research through to late-stage clinical trials. More information is available at www.bioinvent.com.

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