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MarketScreener Homepage  >  Equities  >  OTC Bulletin Board - Other OTC  >  Capstone Therapeutics Corp    


Business Summary
Capstone Therapeutics Corp. is a biotechnology company. The Company is engaged in developing a pipeline of peptides and other molecules aimed at helping patients with under-served medical conditions. The Company entered into a joint venture, LipimetiX Development, Inc., to develop Apo E mimetic peptide molecule AEM-28 and its analogs for the treatment for Homozygous Familial Hypercholesterolemia, Acute Hypertriglyceridemic Pancreatitis, diabetic dyslipidemia and other hyperlipidemic indications. Apolipoprotein E is a 299 amino acid protein that plays a role in lipoprotein metabolism. AEM-28 is a 28 amino acid mimetic of Apo E and AEM-28 and its analogs, including AEM-28-14, a 28 amino acid mimetic of Apo E (with an aminohexanoic acid group and a phospholipid), and both contain a domain that anchors into a lipoprotein surface while also providing the Apo E receptor binding domain, which allows clearance through the heparan sulfate proteoglycan receptors (Syndecan-1) in the liver.
Jock M. Holliman III, MBA651987Executive Chairman & Chief Executive Officer
Leslie M. Taeger, CPA682006CFO, Principal Accounting Officer & Senior VP
Fredric J. Feldman, PhD781991Independent Director
Elwood D. Howse Jr., MBA791987Independent Director
Michael M. Toporek, MBA552017Director
Matthew E. Lipman402017Director
Vote QuantityFloatCompany-owned sharesTotal Float
Stock A 1 54,385 27,086 49.8% 0 0.0% 49.8%
Brookstone Partners 18,541,197 34.1%
Estate Of Lloyd Miller I III 7,554,422 13.9%
BVF Partners LP 2,714,491 4.99%
Jock M. Holliman III, MBA 512,170 0.94%
Fredric J. Feldman, PhD 225,564 0.41%
Elwood D. Howse Jr., MBA 222,703 0.41%
Alimco Financial Corp. 103,000 0.19%
Leslie M. Taeger, CPA 94,574 0.17%
Randolph C. Steer MD, PhD 45,289 0.083%
Company contact information
Capstone Therapeutics Corp.
1275 West Washington Street
Suite 104
Tempe, AZ 85281

Phone : +1.602.286.5520
Web : http://www.capstonethx.com
Sector Biotechnology & Medical Research - NEC
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