Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On February 25, 2020, Krystal Biotech, Inc. (the "Company") announced the appointment of Kathryn Romano as the Company's chief accounting officer. The Company further announced that Tony Riley has resigned as the Company's chief financial officer, effective February 22, 2020.

A press release announcing Ms. Romano's appointment and Mr. Riley's resignation is attached as Exhibit 99.1 to this report.

In connection with his resignation, Mr. Riley and the Company entered into a Separation Agreement and General Release (the "Separation Agreement") pursuant to which (i) Mr. Riley will not receive any cash severance payments following his resignation, and (ii) the Company agreed to modify the vesting terms of certain equity awards previously granted to Mr. Riley to provide for partial vesting during Mr. Riley's most recent annual period of service. Pursuant to the Separation Agreement, Mr. Riley executed a release of all claims and reaffirmed his post-employment obligations to the Company.




                  Item 9.01   Financial Statements and Exhibits.


(d) Exhibits.



              Exhibit
                No.     Description

              99.1        Press Release dated February 25, 2020.

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