Log in
E-mail
Password
Remember
Forgot password ?
Become a member for free
Sign up
Sign up
New member
Sign up for FREE
New customer
Discover our services
Settings
Settings
Dynamic quotes 
OFFON

MarketScreener Homepage  >  Equities  >  Swiss Exchange  >  Lonza Group    LONN   CH0013841017

LONZA GROUP

(LONN)
  Report  
SummaryQuotesChartsNewsRatingsCalendarCompanyFinancialsConsensusRevisions 
News SummaryMost relevantAll newsPress ReleasesOfficial PublicationsSector newsMarketScreener StrategiesAnalyst Recommendations

Lonza : Mesoblast and Lonza Enter Into Agreement for Commercial Manufacture of Mesoblast's Potential First United States Allogeneic Cell Therapy

share with twitter share with LinkedIn share with facebook
share via e-mail
0
10/16/2019 | 06:17pm EST

MELBOURNE, Australia and NEW YORK and BASEL, Switzerland, Oct. 16, 2019 (GLOBE NEWSWIRE) -- Mesoblast (ASX:MSB; Nasdaq:MESO) and Lonza (SWX: LONN) announced today that they have entered into an agreement for commercial manufacture of Mesoblast’s lead allogeneic (off-the-shelf) cell therapy product candidate, remestemcel-L for pediatric steroid-refractory acute graft versus host disease (aGVHD). This agreement will facilitate inventory build ahead of the planned United States (US) market launch of remestemcel-L and commercial supply to meet Mesoblast’s long-term market projections. 

Mesoblast expects to complete filing of the rolling Biologics License Application (BLA) submission to the US Food and Drug Administration (FDA) by the end of this year. On acceptance of the filing, the product candidate is eligible for FDA priority review under its existing Fast Track designation, providing for an expedited review period. If approved, the US launch of remestemcel-L is expected to occur next year.

The agreement provides for Lonza to expand its Singapore cGMP facilities if required to meet long-term growth and capacity needs for the product. Additionally, it anticipates introduction of new technologies and process improvements which are expected to result in significant increases in yields and efficiencies. 

Mesoblast Chief Executive Dr Silviu Itescu stated: “This commercial manufacturing agreement with Lonza for our lead product candidate is designed to ensure that we are in a position to meet projected commercial demand as we plan to roll out the first of our allogeneic cell therapies to people around the world in need of life-saving and disease-modifying products.”

Alberto Santagostino, SVP Head of Cell & Gene Technologies, Lonza Pharma & Biotech said: “Mesoblast is a true trailblazer, leading the way in developing life-changing cell therapies and working hard to soon make them available to large numbers of patients. This agreement builds on the successful partnership and alliance between our two companies over the years. As we also enter new partnerships with early-stage companies on one side, Mesoblast shows the path of success in reaching commercialization on the other. We are committed for the long run with Mesoblast, to continue to grow and deliver cell therapies to all patients in need, together.”

About Mesoblast
Mesoblast Limited (ASX: MSB; Nasdaq: MESO) is a world leader in developing allogeneic (off-the-shelf) cellular medicines. The Company has leveraged its proprietary cell therapy technology platform to establish a broad portfolio of commercial products and late-stage product candidates. Two products have been commercialized in Japan and Europe by its licensees, and it has established commercial partnerships in Europe and China for certain Phase 3 assets. In the United States, Mesoblast has initiated submission of a rolling Biologics License Application to the FDA to seek approval of its product candidate for acute graft versus host disease following a successful Phase 3 trial, and is completing Phase 3 trials for its advanced heart failure and chronic low back pain product candidates. Mesoblast’s proprietary manufacturing process yields industrial-scale, frozen, off-the-shelf, cellular medicines based on its mesenchymal lineage cell platform technology. These cell therapies, with defined pharmaceutical release criteria, are planned to be readily available to patients worldwide. Mesoblast has locations in Melbourne, New York, Singapore and Texas and is listed on the Australian Securities Exchange (MSB) and on the Nasdaq (MESO). For more information, please see www.mesoblast.com, LinkedIn: Mesoblast Limited and Twitter: @Mesoblast

Mesoblast’s Forward-Looking Statements
This announcement includes forward-looking statements that relate to future events or our future financial performance and involve known and unknown risks, uncertainties and other factors that may cause our actual results, levels of activity, performance or achievements to differ materially from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements. We make such forward-looking statements pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 and other federal securities laws. Forward-looking statements should not be read as a guarantee of future performance or results, and actual results may differ from the results anticipated in these forward-looking statements, and the differences may be material and adverse. Forward-looking statements include, but are not limited to, statements about the timing, progress and results of Mesoblast’s preclinical and clinical studies; Mesoblast’s ability to advance product candidates into, enroll and successfully complete, clinical studies; the timing or likelihood of regulatory filings and approvals; and the pricing and reimbursement of Mesoblast’s product candidates, if approved. You should read this press release together with our risk factors, in our most recently filed reports with the SEC or on our website. Uncertainties and risks that may cause Mesoblast’s actual results, performance or achievements to be materially different from those which may be expressed or implied by such statements, and accordingly, you should not place undue reliance on these forward-looking statements. We do not undertake any obligations to publicly update or revise any forward-looking statements, whether as a result of new information, future developments or otherwise.

About Lonza
Lonza is an integrated solutions provider that creates value along the Healthcare Continuum®. Through our Pharma Biotech & Nutrition segment and our Specialty Ingredients segment businesses, we harness science and technology to serve markets along this continuum. We focus on creating a healthy environment, promoting a healthier lifestyle and preventing illness through consumers' preventive healthcare, as well as improving patient healthcare by supporting our customers to deliver innovative medicines that help treat or even cure severe diseases. Patients and consumers benefit from our ability to transfer our pharma know-how to the healthcare, hygiene and fast-moving consumer goods environment and to the preservation and protection of the world where we live. Founded in 1897 in the Swiss Alps, Lonza today is a well-respected global company with more than 100 sites and offices and approximately 15,500 full-time employees worldwide at the end of 2018. The company generated sales of CHF 5.5 billion in 2018 with a CORE EBITDA of CHF 1.5 billion. Further information can be found at www.lonza.com.

Additional Information and Disclaimer by Lonza
Lonza Group Ltd has its headquarters in Basel, Switzerland, and is listed on the SIX Swiss Exchange. It has a secondary listing on the Singapore Exchange Securities Trading Limited (“SGX-ST”). Lonza Group Ltd is not subject to the SGX-ST’s continuing listing requirements but remains subject to Rules 217 and 751 of the SGX-ST Listing Manual. Certain matters discussed in this news release may constitute forward-looking statements. These statements are based on current expectations and estimates of Lonza Group Ltd, although Lonza Group Ltd can give no assurance that these expectations and estimates will be achieved. Investors are cautioned that all forward-looking statements involve risks and uncertainty and are qualified in their entirety. The actual results may differ materially in the future from the forward-looking statements included in this news release due to various factors. Furthermore, except as otherwise required by law, Lonza Group Ltd disclaims any intention or obligation to update the statements contained in this news release.

For further information, please contact:

Mesoblast

Julie Meldrum
 
Corporate Communications 
Mesoblast 
T: +61 3 9639 6036 
E: julie.meldrum@mesoblast.com 


Schond Greenway
Mesoblast
T: +1 212 880 2060
E: schond.greenway@mesoblast.com

Lonza

Dr Kristin Koehler
Investor Relations
Lonza Group Ltd
T: +41 61 316 8782
E: Kristin.koehler@lonza.com

Dr Sanna Fowler
Head of External Communications
Lonza Group Ltd
T: 41 61 316 8929
E: sanna.fowler@lonza.com

mesoblast logo.jpg

Source: Mesoblast Limited

2019 GlobeNewswire, Inc., source Press Releases

Stocks mentioned in the article
ChangeLast1st jan.
LONZA GROUP -0.24% 335.6 Delayed Quote.32.08%
MESOBLAST LIMITED 1.86% 1.915 End-of-day quote.62.07%
share with twitter share with LinkedIn share with facebook
share via e-mail
0
Latest news on LONZA GROUP
11/27Pfizer, Novartis lead $2 billion spending spree on gene therapy production
RE
11/21LONZA : Navrogen Inc. and Lonza Sign Agreement to Use Lonza's GS Gene Expression..
AQ
11/14LONZA : New eCHO Basal Medium and Feed Facilitates Late-Stage Cell Viability and..
AQ
11/12Board Announcement
TE
11/06CRYOPORT : Lonza Partners with Cryoport and Strengthens its 'Vein-to-vein' Deliv..
AQ
10/29LONZA : to Host New Webinar 'Paper to EBR in 9 Months How a Strong Collaboration..
AQ
10/23LONZA : Announces Short, Routine Shutdown of Niacinamide Plant in Nansha for Mai..
AQ
10/18MESOBLAST : and Lonza Enter GVHD Commercial Manufacturing Agreement
AQ
10/17LONZA : Strengthens Sports Nutrition Portfolio with the Launch of Vegan MuscleGu..
AQ
10/17MESOBLAST : and Lonza Enter into Agreement for Commercial Manufacture of Mesobla..
AQ
More news
Financials (CHF)
Sales 2019 5 898 M
EBIT 2019 1 202 M
Net income 2019 723 M
Debt 2019 3 213 M
Yield 2019 0,85%
P/E ratio 2019 34,6x
P/E ratio 2020 28,8x
EV / Sales2019 4,77x
EV / Sales2020 4,41x
Capitalization 24 917 M
Chart LONZA GROUP
Duration : Period :
Lonza Group Technical Analysis Chart | MarketScreener
Full-screen chart
Technical analysis trends LONZA GROUP
Short TermMid-TermLong Term
TrendsBearishNeutralBullish
Income Statement Evolution
Consensus
Sell
Buy
Mean consensus OUTPERFORM
Number of Analysts 19
Average target price 374,86  CHF
Last Close Price 335,60  CHF
Spread / Highest target 37,7%
Spread / Average Target 11,7%
Spread / Lowest Target -18,1%
EPS Revisions
Managers
NameTitle
Marc Funk Chief Executive Officer
Albert M. Baehny Chairman
Rodolfo Savitzky Chief Financial Officer
Patrick Aebischer Vice Chairman
Margot A. Scheltema Independent Director
Sector and Competitors
1st jan.Capitalization (M$)
LONZA GROUP32.08%25 344
IQVIA HOLDINGS INC.24.69%28 106
INCYTE CORPORATION43.91%19 711
SEATTLE GENETICS, INC.100.97%19 516
CELLTRION, INC.--.--%18 622
GALAPAGOS133.43%13 527