The robot will be the star of the AI show, but Musk is also expected to discuss Tesla's long-delayed self-driving technology. In May, Musk said that the world's most valuable carmaker would be "worth basically zero" without achieving full self-driving capability, and it faces growing regulatory probes, as well as technological hurdles.
"There will be lots of technical detail & cool hardware demos," Musk wrote on Twitter late on Wednesday, adding the event was aimed at recruiting engineers.
Tesla's live demonstration record is mixed. Launches typically draw cheers, but in 2019 when Musk had an employee hurl a steel ball at the armored window of a new electric pickup truck, the glass cracked.
The key test for the robot is whether it can handle unexpected situations.
Musk announced Tesla's plan for humanoid robots at its AI day in August last year and delayed this year's event from August to have its robot prototype working, with a plan to start production possibly next year.
Tesla teased the unveiling of the bot on social media with an image of metallic robotic hands making a heart shape. But building human-like, versatile hands that can manipulate different objects is extremely challenging, said Heni Ben Amor, a robotics professor at Arizona State University.
Initially, Optimus, an allusion to the powerful and benevolent leader of the Autobots in the Transformers media franchise, would perform boring or dangerous jobs, including moving parts around Tesla factories or attaching a bolt to a car with a wrench, according to Musk.
"There's so much about what people can do dexterously that's very, very hard for robots. And that's not going to change whether the robot is a robot arm or whether it's in the shape of a humanoid," Jonathan Hurst, chief technology officer at Agility Robotics, a humanoid robot firm, told Reuters.
Musk has said that in the future robots could be used in homes, making dinners, mowing the lawn and caring for the elderly, and even becoming a "buddy" for humans or a sex partner.
He is due at Friday's event to give updates on Tesla's much-delayed plan to launch self-driving cars, and on its high-speed computer, Dojo, which was unveiled last year and the company has said is integral to its development of self-driving technology.
Musk has said he expects Tesla will achieve full self-driving this year and mass produce a robotaxi with no steering wheel or pedal by 2024.
At an "Autonomy" event in 2019, Musk promised 1 million robotaxis by 2020 but has yet to deliver such a car.
(Reporting by Hyunjoo Jin; Additional reporting by Akash Sriram; Editing by Peter Henderson and Daniel Wallis)
By Hyunjoo Jin