MedinCell : provides a portfolio update for J.P. Morgan Healthcare Conference 2020 01.13.2020

MedinCell provides a portfolio update for J.P. Morgan Healthcare Conference 2020

MedinCell is attending the J.P. Morgan Healthcare Conference 2020San Francisco, 13-16Jan., 2020

Euronext: MEDCL • Montpellier - France • January 13, 2020 • 10:00 pm (CET)

MedinCell's portfolio of long-acting injectable products progresses well. All innovative products are based on its proprietary BEPO® technology combined with active ingredients already known and marketed.

MedinCell's portfolio includes three products at clinical stage:

• Interim analysis of the current phase 3 clinical trials of the lead asset (mdc-IRM, maintenance treatment of schizophrenia) is expected during the second half of 2020
• The phase 2 clinical trials of a second asset (mdc-CWM,post-operative pain and inflammation management) are ongoing
• The third asset (mdc-TJK, antipsychotic) is in phase 1

Several candidates for clinical development are at formulation or preclinical stage. In particular, results of the ongoing studies of four programs should make it possible to select their candidate formulations in 2020: mdc-GRT,organ transplant ; mdc-WWM,contraception ; mdc-NVA,pain ; mdc-KPT,pain / animal health.

	PROGRAMS AT CLINICAL STAGE
Subcutaneous injection
mdc-IRM	The phase 3 clinical trials are ongoing with an interim analysis in the
Maintenance treatment of schizophrenia	second half of 2020 contingent upon the projected recruitment rate and
Partner: Teva Pharmaceuticals	patient relapse events.
	(Press release of December 3, 2019)
mdc-TJK	The first-in-human study for the investigational long-acting injectable
Antipsychotic	antipsychotic mdc-TJK has started in Q4 2019. The results of this study,
Partner: Teva Pharmaceuticals	expected during 2021, will inform future development.
	(Press release of December 3, 2019)
Intraarticular injection
mdc-CWM	The 20 participants have completed their 3-monthfollow-up visit last
post-operative pain and inflammation	Summer. The analysis of the data is being completed by our partner and
Partnered program	its subcontracted clinical research organization. 12-month trial
	completion is scheduled in March 2020. Our partner plans to meet with
	the FDA in the meantime to discuss the current findings and how to
	progress in the next trial moving forward.
	(Press release of September 25, 2019)
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NEXT POTENTIAL CANDIDATES FOR IND/IMPD
Subcutaneous injection
mdc-ANG	Current status: Preclinical
Antipsychotic	Preclinical work continues to progress and will inform a decision on
Partner: Teva Pharmaceuticals	further development expected in the second half of 2020.
	Press release of July 9, 2019
mdc-GRT	Current status: Formulation
Organ transplant	Full results of ongoing studies should make it possible to select the
MedinCell program	candidate formulation in 2020.
mdc-WWM	Current status: Formulation
Contraception	Full results of ongoing studies should make it possible to select the
Partner: Bill & Melinda Gates Foundation	candidate formulation in 2020.
mdc-STG	Current status: Formulation
Indication: confidential
MedinCell program
mdc-KPT (animal health)	Current status: Formulation
Pain	Full results of ongoing studies should make it possible to select the
Partner: Cornerstone Animal Health	candidate formulation in 2020.

Perineural injection

The two products are the first in MedinCell's portfolio with perineural administration

mdc-CMV	Current status: Preclinical
Pain	The first preclinical studies are ongoing. The results of this study will
MedinCell program	inform future development and updated timelines. The clinical phase 1
	may not start in Q2 2020.
mdc-NVA	Current status: Formulation
Pain	Full results of ongoing studies should make it possible to select the
MedinCell program	candidate formulation in 2020.

MedinCell news on the last 12 months (press releases available on invest.medincell.com)

MedinCell receives $19 million grant from the Bill & Melinda Gates Foundation for mdc-WWM program - November 28, 2019 mdc-CWM progresses as planned - September 25, 2019

The General Meeting votes to include the "Raison d'être" of the Company in its articles of association- September 10, 2019

New grant from the Bill & Melinda Gates Foundation to develop a best-in-class long acting injectable product for HIV prevention (PrEP) - September 5, 2019

MedinCell partners to address the untapped financial potential in Animal Health - August 28, 2019 Long-acting injectable antipsychotic receives FDA IND clearance to initiate clinical activities - August 26, 2019 MedinCell receives 7,5 M€ from the European Investment Bank (EIB) - July 23, 2019

Third long-acting injectable antipsychotic using MedinCell's technology enters preclinical development - July 9, 2019

MedinCell demonstrates in vivo the efficacy of the first injectable combining surgical anesthesia and 3 days opioid free postoperative pain management - March 11, 2019

MedinCell receives 2nd part of the grant from the Bill & Melinda Gates Foundation - January 24, 2019

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About MedinCell

MedinCell is a clinical stage pharmaceutical company that develops a portfolio of long-acting injectable products in various therapeutic areas by combining its proprietary BEPO® technology with active ingredients already known and marketed. Through the controlled and extended release of the active pharmaceutical ingredient, MedinCell makes medical treatments more efficient, particularly thanks to improved compliance, i.e. compliance with medical prescriptions, and to a significant reduction in the quantity of medication required as part of a one-off or chronic treatment. The BEPO® technology makes it possible to control and guarantee the regular delivery of a drug at the optimal therapeutic dose for several days, weeks or months starting from the subcutaneous or local injection of a simple deposit of a few millimeters, fully bioresorbable. Based in Montpellier, MedinCell currently employs more than 130 people representing over 25 different nationalities.

www.medincell.com

MedinCell	NewCap	NewCap
David Heuzé	Louis-Victor Delouvrier / Alexia Faure	Nicolas Merigeau
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This press release may contain forward-looking statements, especially on the Company's progress of its clinical trials. Although the Company believes that its expectations are based on reasonable assumptions, any statements other than statements of historical facts that may be contained in this press release relating to future events are subject to change without notice, factors beyond the Company's control and the Company's financial capabilities.

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