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Patent Issued for Auto-Injector (USPTO 10010683)

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07/12/2018 | 11:43pm CEST

By a News Reporter-Staff News Editor at Pharma Business Week -- According to news reporting originating from Alexandria, Virginia, by NewsRx journalists, a patent by the inventors Henley, Thomas (Cambridgeshire, GB); Cross, David (Letchworth, GB); Jennings, Douglas Ivan (Herts, GB); McGinley, Ryan Anthony (Cambridgeshire, GB), filed on April 20, 2016, was published online on July 3, 2018 (see also Sanofi).

The assignee for this patent, patent number 10010683, is Sanofi (Frankfurt am Main, DE).

Reporters obtained the following quote from the background information supplied by the inventors: "Administering an injection is a process which presents a number of risks and challenges for users and healthcare professionals, both mental and physical.

"Injection devices typically fall into two categories--manual devices and autoinjectors. In a conventional manual device, a user must provide force to drive a medicament through a needle. This is typically done by some form of button/plunger that has to be continuously pressed during the injection. There are numerous disadvantages for the user from this approach. For example, if the user stops pressing the button/plunger, the injection will stop and may not deliver an intended dose to a patient. Further, the force required to push the button/plunger may be too high for the user (e.g., if the user is elderly). And, aligning the injection device, administering the injection and keeping the injection device still during the injection may require dexterity which some patients (e.g., elderly patients, children, arthritic patients, etc.) may not have.

"Autoinjector devices aim to make self-injection easier for patients. A conventional autoinjector may provide the force for administering the injection by a spring, and trigger button or other mechanism may be used to activate the injection. Autoinjectors may be single-use or reusable devices.

"There remains a need for an improved autoinjector."

In addition to obtaining background information on this patent, NewsRx editors also obtained the inventors' summary information for this patent: "It is an object of the present invention to provide a novel syringe and novel reusable autoinjector for operating the syringe.

"In an exemplary embodiment, an autoinjector according to the present invention comprises a case, a drive carriage disposed in the case, and a plunger coupled to the drive carriage. The plunger is adapted to releasably engage a needle retraction mechanism in a syringe. Translation of the drive carriage in a distal direction relative to the case causes the plunger to engage the needle retraction mechanism and translation of the drive carriage in a proximal direction relative to the casing case the plunger to needle retraction mechanism the stopper.

"In an exemplary embodiment, the autoinjector further comprises a drive spring biasing the drive carriage relative to the case.

"In an exemplary embodiment, the autoinjector further comprises a plunger spring biasing the plunger relative to the drive carriage.

"In an exemplary embodiment, the plunger includes proximal resilient arms adapted to engage a distal aperture in the drive carriage.

"In an exemplary embodiment, the autoinjector further comprises a latch tube coupled to the plunger. The latch tube includes resilient arms. The plunger includes distal resilient arms adapted to engage a proximal aperture in the latch tube. When the drive carriage abuts the latch tube, the proximal resilient arms are deflected by the proximal aperture in the latch tube and the plunger translates in the proximal direction relative to the drive carriage under a force of the plunger spring.

"In an exemplary embodiment, the case includes a stem adapted to engage a proximal end of the plunger. When the drive carriage separates from the latch tube, the drive carriage and the plunger translate in the proximal direction relative to the case until the stem engages the distal end of the plunger and prevents the plunger from further translation while allowing further translation of the drive carriage. The further translation of the drive carriage causes the proximal resilient arms to deflect and re-engage the distal aperture of the drive carriage.

"In an exemplary embodiment, the autoinjector further comprises an interlock sleeve slidably disposed in the case, and a sleeve spring adapted to apply a biasing force to the interlock sleeve relative to the case.

"In an exemplary embodiment, the autoinjector further comprises a latch sleeve slidably disposed in the case, and a latch sleeve spring adapted to apply a biasing force to the latch sleeve relative to the case. When the interlock sleeve translates in the proximal direction relative to the case, hooks on the interlock sleeve abut the resilient arms on the latch tube and prevent the resilient arms from deflecting. The resilient arms prevent the drive carriage from abutting the latch tube. When the interlock sleeve translates in the distal direction relative to the case, the hooks on the interlock sleeve disengage the resilient arms on the latch tube, the resilient arms deflect and the drive carriage engages the latch tube.

"In an exemplary embodiment, the autoinjector further comprises a slider movably arranged on the case. The slider includes an internal boss adapted to engage the drive carriage.

"In an exemplary embodiment, the autoinjector further comprises a case release pin slidably disposed in the case. The pin (30) has an outer surface adapted to engage the slider and an inner surface adapted to engage a latch arm in the case. Movement of the slider causes movement of the pin to disengage the latch arm from the case.

"Further scope of applicability of the present invention will become apparent from the detailed description given hereinafter. However, it should be understood that the detailed description and specific examples, while indicating preferred embodiments of the invention, are given by way of illustration only, since various changes and modifications within the spirit and scope of the invention will become apparent to those skilled in the art from this detailed description."

For more information, see this patent: Henley, Thomas; Cross, David; Jennings, Douglas Ivan; McGinley, Ryan Anthony. Auto-Injector. U.S. Patent Number 10010683, filed April 20, 2016, and published online on July 3, 2018. Patent URL: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=10010683.PN.&OS=PN/10010683RS=PN/10010683

Keywords for this news article include: Pharmaceutical Companies, Sanofi, Business.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2018, NewsRx LLC

(c) 2018 NewsRx LLC, source Health Newsletters

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