Log in
E-mail
Password
Remember
Forgot password ?
Become a member for free
Sign up
Sign up
Settings
Settings
Dynamic quotes 
OFFON

MarketScreener Homepage  >  News  >  Companies  >  All News

News : Companies
Latest NewsCompaniesMarketsEconomy & ForexCommoditiesInterest RatesBusiness LeadersFinance ProfessionalsCalendarSectors

West Pharmaceutical Services : Demonstrating Package Performance at Low Temperatures

share with twitter share with LinkedIn share with facebook
share via e-mail
0
09/12/2019 | 12:12pm EDT

Gene and cell therapies require cryo storage - approximately -80oC for genes, and approximately -180oC (i.e., vapor of liquid nitrogen) for cells. This requirement places a very high demand on the packaging to provide both good container closure integrity (CCI) and preservation of drug product viability.

This was discussed in detail in the recent presentation by Matthew Gehrmann (Sr. Scientist, Scientific Communications) titled Low Temperature Storage: Preservation of Cell-and Gene-Based Drug Products at 2019 PDA Biopharmaceuticals Week.

It was shown that the system comprising Daikyo Crystal Zenith® cyclic olefin polymer (COP) vials and West rubber stoppers provided excellent CCI. Because the coefficients of thermal expansion for COP and rubber match more closely than do those of glass and rubber, COP vials are very well suited to cryo storage. It was also shown that the same system provided for stem cell viability after storage at -180oC, by evaluation of recovery, morphology, and biomarker expression.

Types evaluated were:

  • adherent-type human mesenchymal (hMSC's)
  • suspension-type umbilical cord hematopoietic (CD34+)

West is committed to the safe and efficient delivery of drug products to patients - an aspect of which is experimental evaluation of its products under demanding conditions. For more on how West can address cryo storage needs of biologic drug products, contact an Account Manager or Technical Customer Support (TCS) representative.

Crystal Zenith® is a registered trademark of Daikyo Seiko, Ltd. Daikyo Crystal Zenith® technology is licensed from Daikyo Seiko, Ltd.

Disclaimer

West Pharmaceutical Services Inc. published this content on 12 September 2019 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 12 September 2019 16:11:01 UTC

share with twitter share with LinkedIn share with facebook
share via e-mail
0
Latest news "Companies"
01:12aHENNES & MAURITZ : H&M summer collection boosts third quarter sales growth
AQ
01:11aELDORADO GOLD : Greece seeking new mining jobs and higher royalties in talks with Canada's Eldorado Gold
AQ
01:11aAPPLE : challenge to EU over €13bn Irish tax order
AQ
01:11aATLANTIA : chief exec set to step down as bridge probe darkens
AQ
01:11aJP MORGAN CHASE MPANY : US authorities charge JP Morgan metals traders with 'racketeering'
AQ
01:11aMORGAN STANLEY : Endeavor looks to raise $712m in public listing
AQ
01:11aCUSHMAN & WAKEFIELD : City moves who's switching jobs
AQ
01:11aNATIONAL GRID : Former National Grid boss 'heads for City Fibre'
AQ
01:11aVIVENDI : Canal+ pairs up with Netflix in a pay-TV shift
AQ
01:11aKazakh financial group to list in London in boost to market
AQ
Latest news "Companies"