Bruker : Q3 2025 Earnings Webcast (Presentation)

BRUKER CORPORATION (NASDAQ: BRKR)

Q3 2025 Earnings Presentation November 3, 2025

Frank H. Laukien, President & Chief Executive Officer

Gerald Herman, Executive Vice President & Chief Financial Officer Joe Kostka, Director, Investor Relations

Q3 2025

Business Update

Q3 2025: Organic revenue, non-GAAP operating margin, and EPS decline on research instrument demand headwinds in H1-25

Q3 Financials

Q3 2025 Performance; Year-over-Year Changes

• Revenue decrease of -$3.9M, or -0.5%

  • Organic decline -4.5%, with BSI -5.4%, and BEST up +6.9%

  • M&A contribution of +1.1%

  • FX tailwind of +2.9%

• Non-GAAP gross margin: 50.1%, down -110 bps

• Non-GAAP operating margin: 12.3%, down -260 bps

  Revenues [$M]

  -0.5%

  	860.5		864.4

  Q3-25 Q3-24

  
  
  

  Non-GAAP EPS

• GAAP Loss per Share: -$0.41

• Non-GAAP EPS: $0.45, down -25%

  Q3-25

  Q3-24

  -25.0%

  
  
  

  Q3-25 YTD: Revenue growth driven by M&A; non-GAAP operating margin and EPS down on YTD demand, tariff and FX headwinds

  Q3-YTD Financials

Q3 2025 YTD Performance; Year-over-Year Changes

• Revenue increase of $72.5M, or 3.0%

  • Organic revenue down -3.1%, with BSI down -2.9%, BEST down -5.5%

  • M&A contribution of +4.5%

  • FX tailwind of +1.6%

• Non-GAAP gross margin: 50.0%, down -120 bps

• Non-GAAP operating margin: 11.4%, down -290 bps

• GAAP Loss per Share: -$0.25

• Non-GAAP EPS: $1.23, down -25.5%

- including FX headwind of $0.09

Revenues [$M]

+3.0%

		2386.8

2459.3

YTD-25 YTD-24

-25.5%

Non-GAAP EPS

YTD-25

YTD-24

GROUP OVERVIEW

Bruker Group YTD CER Revenue Performance (yoy)

Bruker BIOSPIN Group

• BIOSPIN YTD CER revenue down mid-single digits %

• Growth from lab automation and services

• Challenging Q3-25 comparison with two GHz-class NMRs (>$25m) in Q3-24 revenue

  
  
  

  Bruker CALID Group

• CALID YTD CER revenue up low-DD %, including growth in all divisions

• Strong Microbiology & Infection Diagnostics growth, driven by ELITech MDx

• Life Science Mass Spectrometry traction for recently launched products

  + -Bruker

  © 20252 Bruker

  Q3 2025 Earnings Presentation | November 3, 2025 | 6

• Stable molecular spectroscopy business, with strong orders in Applied markets in Q3-25

  
  
  

  GROUP OVERVIEW

  Bruker Group YTD CER Revenue Performance (yoy)

  Bruker NANO Group

  
  
  

• NANO YTD CER revenue down low single digits %

• Softness in X-Ray Semi and NanoAnalysis industrial research tools

• Solid growth in Spatial Biology, including NanoString

  + -Bruker

  Bruker Energy & Supercon Technologies (BEST) Segment

  • BEST YTD CER revenue down mid-single digits %, net of intercompany eliminations

  • Soft superconductor demand for clinical MRI, with improvements in Q3-25

  • Strong prior year comparison for Research Instruments (RI)

  © 20225 Bruker

  Q3 2025 Earnings Presentation | November 3, 2025 | 7

  
  
  

• Strengthening industrial and applied markets in Japan and North America in Q3-25

US ACADEMIC ORDER EXAMPLES IN Q 3 - 25

Recent NIH- and NSF-funded Orders for Advanced NMR Instruments

• Enabling breakthroughs across scientific research, drug discovery and disease biology research

• Aggregate value of ~$10M, expected to be installed in 2026

• BSI ACA/GOV orders up mid-teens % organically yoy in Q3-25, despite lingering US weakness

NIH-funded 800 MHz NMR ordered by Northwestern University

NIH-funded NMR Relaxometry System ordered by the New York Structural Biology Center

NSF-funded 600/89 MHz NMR with Dynamic Polarization (DNP) ordered by University of Delaware

CBRNE DETECTION

Recent Multi-Year Contracts for Explosives and Chemical Trace Detection in Aviation Security and Defense Sectors

Bruker Detection provides solutions for airline safety, airport passenger and cargo security, and chemical reconnaissance, including after-market consumables and service

>$30M in orders YTD, growing >30% yoy, including:

• >350 Explosive Trace Detectors (ETD) for airports in Brussels, Scandinavia, Saudi Arabia, and South Korea

  • adding to ETDs, consumable and service contracts at Frankfurt, Zuerich, Geneva and other European airports

• Order for >500 chemical reconnaissance systems from

a Central European Ministry of Defense

Detector-Flex delivers fast, reliable explosives trace detection for air cargo and passenger screening

Q3 2025

Financial Update