Health-care companies fell after as a long run-up in the sector paused.
The SPDR Select Health Care exchange-traded fund, which tracks the health care sector of the Standard & Poor's 500, slipped from near all-time highs hit Friday.
Shares of BioMarin fell sharply after the U.S. Food and Drug Administration placed a hold on the clinical trial of a gene therapy because of instances of cancer in a trial on animals.
U.S.-traded shares of Danish biotech company Forward Pharma fell sharply after the company said its appeal of a European patent application ruling was rejected.
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(END) Dow Jones Newswires