Health-care companies fell as traders rotated into sectors with more to gain from rising interest rates.

Australian Pharmaceutical Industries rose after rival drug wholesaler Sigma Healthcare made a proposal worth about $562 million to buy the drug retailer and wholesaler.

Pfizer began a large trial to test its experimental Covid-19 antiviral pill as a prophylaxis for adults living in the same house as a person with the virus.

Write to Rob Curran at rob.curran@dowjones.com

(END) Dow Jones Newswires

09-27-21 1707ET