Notification of transaction by Person Discharging Managerial Responsibilities
("PDMR")

+--+----------------------------+------------------------------+
|1 |Details of the person                                      |
|  |discharging managerial                                     |
|  |responsibilities/person                                    |
|  |closely associated                                         |
+--+----------------------------+------------------------------+
|a)|Name                        |Robert Kaplan                 |
+--+----------------------------+------------------------------+
|2 |Reason for the notification                                |
+--+----------------------------+------------------------------+
|a)|Position/status             |Finance Director              |
+--+----------------------------+------------------------------+
|b)|Initial                     |Initial notification          |
|  |notification/Amendment      |                              |
+--+----------------------------+------------------------------+
|3 |Details of the issuer,                                     |
|  |emission allowance market                                  |
|  |participant, auction                                       |
|  |platform, auctioneer or                                    |
|  |auction monitor                                            |
+--+----------------------------+------------------------------+
|a)|Name                        |Pensana Plc                   |
+--+----------------------------+------------------------------+
|b)|LEI                         |213800H4QP6T9499RU64          |
+--+----------------------------+------------------------------+
|4 |Details of the                                             |
|  |transaction(s): section to be                              |
|  |repeated for (i) each type of                              |
|  |instrument; (ii) each type of                              |
|  |transaction; (iii) each date;                              |
|  |and (iv) each place where                                  |
|  |transactions have been                                     |
|  |conducted                                                  |
+--+----------------------------+------------------------------+
|a)|Description of the financial|Ordinary Shares of £0.001 each|
|  |instrument, type of         |                              |
|  |instrument                  |                              |
+--+----------------------------+------------------------------+
|  |Identification code         |GB00BKM0ZJ18                  |
+--+----------------------------+------------------------------+
|b)|Nature of the transaction   |Sale of shares                |
+--+----------------------------+------------------------------+
|c)|Price(s) and volume(s)      |Price: £0.9225                |
|  |                            |                              |
|  |                            |Volume:37,500                 |
+--+----------------------------+------------------------------+
|d)|Aggregated information      |Aggregated volume: 37,500     |
|  |                            |                              |
|  |                            |Price: £34,593.75             |
+--+----------------------------+------------------------------+
|e)|Date of the transaction     |12 January 2026               |
+--+----------------------------+------------------------------+
|f)|Place of the transaction    |London Stock Exchange         |
+--+----------------------------+------------------------------+


This information was brought to you by Cision http://news.cision.com
https://news.cision.com/pensana-plc/r/directors-dealings,c4292334