On March 3, 2022, Edward Carr, Chief Financial Officer and Chief Accounting Officer of Abeona Therapeutics Inc. (the “Company”), notified the Company of his resignation effective March 31, 2022. Mr. Carr will remain the Company's Chief Accounting Officer and principal financial officer and principal accounting officer through March 31, 2022. Mr. Carr's resignation is not the result of any disagreement with the Company.

Also on March 3, 2022, the Board appointed Joseph Vazzano as Chief Financial Officer effective March 14, 2022. Mr. Vazzano, 38, will serve as the Company's principal financial officer and principal accounting officer effective March 31, 2022. Before joining the Company, Mr. Vazzano served as Chief Financial Officer of Avenue Therapeutics Inc. from February 2019 to January 2022.

Prior to that, he served as Avenue's Vice President of Finance and Corporate Controller since August 2017.