Alexion Pharmaceuticals, Inc. agreed to acquire Caelum Biosciences, Inc. from Fortress Biotech, Inc. (NasdaqCM:FBIO) and others for $500 million on September 28, 2021. Upon closing, Alexion will pay Caelum the agreed option exercise price of approximately $150 million, with the potential for additional payments of up to $350 million upon achievement of regulatory and commercial milestones. The transaction is expected to close on October 5, 2021. Mark McElreath and James Sullivan of Alston & Bird LLP acted as the legal advisors to Caelum Biosciences.

Alexion Pharmaceuticals, Inc. completed the acquisition of Caelum Biosciences, Inc. from Fortress Biotech, Inc. (NasdaqCM:FBIO) and others on October 5, 2021. The additional payment of $350 million includes: $75 million upon Biologics License Application approval of CAEL-101, $50 million upon CAEL-101 attaining $250 million in annual net sales; $50 million upon CAEL-101 attaining $500 million in annual net sales; $75 million upon CAEL-101 attaining $750 million in annual net sales; and $100 million upon CAEL-101 attaining $1 billion in annual net sales.