Business description: Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is engaged in discovering, developing, manufacturing and commercializing novel therapeutics based on ribonucleic acid interference (RNAi). Its marketed products include AMVUTTRA (vutrisiran) for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR) in adults ; ONPATTRO (patisiran) for the treatment of the polyneuropathy of hATTR amyloidosis in adults; GIVLAARI (givosiran) for the treatment of adults with acute hepatic porphyria; OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1, and Leqvio (inclisiran), which is being developed and commercialized by its partner, Novartis AG, for the treatment of adults with hypercholesterolemia or mixed dyslipidemia. The Company’s clinical development programs include Cemdisiran, Zilebesiran, Elebsiran, Mivelsiran, ALN-6400, and ALN-HTT02. It is developing Cemdisiran to treat complement-mediated diseases.

Number of employees: 2,500

Sales by Activity: Alnylam Pharmaceuticals, Inc.

Fiscal Period: December 2021 (USD) 2022 (USD) 2023 (USD) 2024 (USD) 2025 (USD)

Discovery, Development, Manufacturing and Commercialization of Rnai Therapeutics

844M 1.04B 1.83B 2.25B 3.71B

Geographical breakdown of sales: Alnylam Pharmaceuticals, Inc.

Fiscal Period: December 2021 (USD) 2022 (USD) 2023 (USD) 2024 (USD) 2025 (USD)

United States

325M 473M 689M 934M 2.07B

Europe

260M 315M 399M 516M 651M

Rest of World

77.03M 107M 153M 196M 268M

Executive Committee: Alnylam Pharmaceuticals, Inc.

Manager TitleAgeSince
Chief Executive Officer 63 2021-12-31
Director of Finance/CFO 58 2019-08-12
Compliance Officer - 2022-09-20
Chief Tech/Sci/R&D Officer 58 2016-08-31
Chief Tech/Sci/R&D Officer 58 2014-10-28

Composition of the Board of Directors: Alnylam Pharmaceuticals, Inc.

Director TitleAgeSince
Director/Board Member 80 2012-04-22
Chairman 65 2023-01-04
Director/Board Member 72 2015-12-17
Director/Board Member 63 2021-10-27
Director/Board Member 66 2018-05-31
Director/Board Member 70 2019-01-09
Director/Board Member 70 2020-03-01
Director/Board Member 74 2022-08-21
Director/Board Member 69 2023-03-06
Director/Board Member 60 2026-01-04

Shareholders: Alnylam Pharmaceuticals, Inc.

NameStocks%Valuation
Fidelity Management & Research Co. LLC
10.92 %
14,576,437 10.92 % 4 402 M $
Capital Research & Management Co. (World Investors)
8.091 %
10,802,348 8.091 % 3 262 M $
Capital Research & Management Co. (Global Investors)
7.094 %
9,471,181 7.094 % 2 860 M $
BlackRock Advisors LLC
6.26 %
8,357,377 6.26 % 2 524 M $
Vanguard Portfolio Management LLC
4.862 %
6,491,280 4.862 % 1 960 M $

Company details: Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc.

675 West Kendall Street

02142, Cambridge

+617 551 8200

http://www.alnylam.com
address Alnylam Pharmaceuticals, Inc.(ALNY)

Other Pharmaceuticals

Change 5-day change 1-year change 3-year change Capi.($)
-0.43%+1.84%-1.49%+54.31% 39.75B
+1.56%+7.53%+43.71%+160.49% 1,021B
+1.25%+7.47%+53.35%+50.04% 571B
+0.66%+4.40%+19.62%+64.58% 398B
-0.90%+5.62%+21.96%+15.95% 319B
-0.74%+2.45%+24.48%+14.40% 283B
+0.84%+5.18%+22.37%+31.44% 272B
+0.88%+2.97%+18.68%+60.22% 186B
+5.05%+4.16%-45.54%-48.24% 185B
-2.00%-4.36%+12.06%+58.45% 156B
Average +0.63%+2.88%+16.92%+46.16% 342.97B
Weighted average by Cap. +0.94%+4.79%+29.09%+72.71%
Trader
Investor
Global
Quality
ESG MSCI
AA
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
30
Last Close Price
297.69USD
Average target price
441.31USD
Spread / Average Target
+48.24%

Quarterly revenue - Rate of surprise

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