AN EXPERT IN SENSORY ANALYSIS
DELIVERING FOODTECH SOLUTIONS AND PIONEERING MEDTECH SOLUTIONS,
READY TO SCALE
Copyright 2019 - Alpha MOS | Confidential and Proprietary |
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Alpha MOS Proprietary | 2 |
Investment case: An expert in sensory analysis delivering FoodTech solutions and pioneering MedTech solutions, ready to scale
25 years experience in sensory analysis
Providing critical sensory analysis services based onVolatile
Organic Compound (VOC)
Bringinga new solution to complement human sensory panels currently used in analysis, a human intensive and costly process
Leadership position in the Food & beverage industry for quality testing in product development with Top100 key accounts and a strategic partnership withCoca-Cola
25 years experience and know how
Fablesssince 2018
With a strong technology edge
A unique VOC sensing and analysis technology
Ability to combine the right instrumentwith a proprietary software cumulating 25 years experienceto capture and
analyze sensory characteristics in multiple environments
Successfully validatedwith world-class F&B customers in the Product Development phase
Easy to usesolutions usable both in R&D centers and production sites
10 patent families granted
2021 objectives
FoodTech | MedTech | |
Revenue |
And a clear strategic roadmap
to address fast growing segments and promising markets
>15M€ | Launching |
manufacturing | |
CAGR 2018-2021 | with the right |
MedTech partner |
FoodTech
($5bn market for product testing)
Leveraging our validated platform and strong customer relations to expand beyond product development into quality control directly on production sites, enabling our clients' shift towards industry 4.0
New product design ready to scale
Signing new key alliances and continue to invest in R&D
- Growing market position focusing onTop100 Food & Beverage key accounts
MedTech
($10bn market for glucose monitoring devices)
Miniaturizing our patented solution to build an economical and non-invasive breath analyzer platform to monitor chronic conditions, starting with diabetes.
Successful early clinical trial (>100 patients) and identification of breath VOC for diabetic test.
Ready for demos with partners and customers
- Fueling development towards FDApre-submission and product development
>45% | in 2021 |
EBITDA Margin | |
>15% |
Alpha MOS Proprietary | 3 |
Volatile Organic Compounds (VOC) are critical indicators in sensory analysis
Most scents or odors are associated with VOC: organic chemicals that evaporate from the liquid or solid form of the compound and enter the surrounding air
In Food & Beverage, VOC can vary greatly in quantity driving a significant impact on the final product's aroma and perceived quality
In the Medical sector, VOC can also be found in the exhaled breath of humans and are a critical indicator of normal metabolic activity or pathological disorders
Alpha MOS Proprietary | 4 |
25 years of experience in VOC based sensory analysis solutions
Ready to scale up
We are an expert in VOC based sensory analysis solutions across multiple markets: food, beverage, medical,…
50 employees (March 1, 2019)
>95% international sales
1,000+ instruments installed globally
Fabless company
10 Patent families granted
Traded on EuroNext Paris
France
America | Japan |
China
Alpha MOS Proprietary | 5 |
A unique VOC analysis technology
25 years of Experience & Unique Combination of Skills
Alpha MOS unique technology leveraging 10 patent families
Design, specify and build the right instrument / | X | Leverage Proprietary All-in-One Software | ||||||||||||||
hardware to capture VOC characteristics | to analyze VOC characteristics | |||||||||||||||
Fluidic | Bio- | Sensor | Electronic | Firmware | Data pre- | Database of | Machine | |||||||||
chemistry | Technology | processing | compounds | learning | ||||||||||||
Delivering VOC analysis solutions across multiple markets
Alpha MOS Proprietary | 6 |
An automated VOC analysis solution
Instrument | Software | Services | ||
Maintenance | ||
E-training | ||
~100 000 VOC | Data Analytics | |
> 2 000 sensory attributes | Lab services: customer specific | |
Artificial Intelligence | models & applications | |
Heracles /Astree/Iris | Proprietary All-in-One Software | Customer operations | ||
Detecting desirable VOC
- undesirable VOC(cross contamination, migrants from packaging, or unpleasant by-products of microbial action)
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Alpha MOS Proprietary
Successfully validated VOC analysis technology with world-class R&D centers
Food | Beverage | Others | ||
Vegetable | Dairy | Waters | Juices | |
Oils | & Milk | Petfood, Packaging, Cosmetics, | ||
Aromas & | Seasonings | Coffee | Sodas | Pharma… |
Flavors | & Sauces | Tea | & CSD | |
Alpha MOS Proprietary | 8 |
Ready to deliver solutions on other fast-growing markets and segments
Food & Beverage |
R&D Production
$5bn
Medical |
Glucose monitoring devices
$10bn |
Leveraging our existing client relationships to expand from Product Developmenttesting in the labs to quality control directly on production sites
Miniaturizing our patented solution to build an economical andnon-invasivebreath analyzer platform to monitor chronic conditions - starting with diabetes
Alpha MOS unique VOC analysis technology
Hardware expertise | X | Software and data analysis capabilities |
Alpha MOS Proprietary
--- | |
F&B total addressable market size based on Alpha MOS estimates | 9 |
Glucose monitoring device addressable market: https://aabme.asme.org/posts/innovations-to-disrupt-blood-glucose-monitoring-market) |
Best positioned to enable F&B customers' | ||||
shift towards Industry 4.0 | ||||
Pain points | Customer's Benefits with Alpha MOS | |||
Market | Frequent change-overs | Versatile monitoring tool | ||
« Just in time » production, | ||||
constraints | High throughput analysis capabilities | |||
limited control on production parameters | ||||
Subjective monitoring | Objective monitoring | |||
Sensory | / variation of flavors | (>90% of correct evaluation vs 75% for panel) | ||
Partial sampling (samples / day) | Up to 200 samples / day | |||
Analysis | ||||
Delays in the workflow | Immediate result display | |||
Financial | Off-taste batch / production stop financial losses | Increased production yield | ||
Non-quality costs | Reduced costs: direct (test) + non quality | |||
constraints | ||||
Brand image risk | Protecting brand reputation | |||
Human | Uncomfortable and repetitive human tests | User-friendly and easy-to-use, leveraging Machine-Learning | ||
Dimension | Increased consumer concerns on F&B quality | Product quality improvement for consumers | ||
Improved operational efficiency / Enhanced working conditions
for employees / Secured Brand Reputation
Alpha MOS Proprietary | 10 |
Already bringing key benefits for the F&B market
Example of use cases at production sites
Fruit Juices
Fermentation level
Off taste such as earthy, sulfurous, plastic, etc… Taste modification by fermented juice after pasteurization
Various fruit juice foot print
Vegetable Oils
Detection of Hexane level
Mixed quality or mixed origin detection (ex: fraudulent)
Rancid off note - major off taste for oil Various oils foot print
Carbonated Soft Drink (CSD)
Off taste such as earthy, sulfurous, medical, etc… Plastic or metallic taste detection
Multiple CSD foot print
Cross contamination detection
Cleaning In Place (CIP)
Cross contamination
Detergent (acid or basic) detection Rinse water analysis
Reduction of number of rinse cycle
Reduction of production cost: up to 5K$ per rinse
Alpha MOS Proprietary | 11 |
Leverage our technology to address the MedTech sector and solve the diabetes analysis issue
- dedicatedCalifornia-based subsidiary: BOYDSense
Miniaturizing our platform to offer an economical andnon-invasivebreath analyzer to monitor chronic conditions, starting with glucose.
Bringing a new solution for glucose
measurement: Non invasive, easy,
convenient,
quick,
real time information of glycemic trends.
platform: | ||
available and tested for | AI | |
glucose measurements | ||
Miniaturized solution |
Alpha MOS unique VOC analysis technology
Hardware expertise | Software and data |
analysis capabilities | |
Alpha MOS Proprietary | 12 |
$10 bn: market size of glucose monitoring devices
High barriers of high cost and poor user experience lead to low adherence for current standards of care and hinders adoptionby people that could benefit from glycemic con such obesity, prediabetes, and diabetes.
Alpha MOS Proprietary
Tackle a new gigantic market with a disruptive solution for glucose measurement
Blood
Glucose
Monitor
(BGM)
AFFORDABLE | >$26/mo3 |
ContinuousExperimental
Glucose
Monitor
(CGM)
$100-$300/mo1,2
Fast growing market in US > 600k users in 2018 vs 300k users in2017
NON-INVASIVE
---
1. Dexcom price sheet. https://s3-us-west-2.amazonaws.com/dexcompdf/HCP_Website/LBL016019+2018+Reimbursement+Sheet.pdf
2. Abbott and Dexcom price summary: https://www.closeconcerns.com/knowledgebase/r/55a45fe3#How_Does_FreeStyle_Libres_US_Pricing_Compare_to_Dexcom
3. $.20/strip @ recommended 4x / day (by American Diabetes Association).http://www.diabetes.org/living-with-diabetes/recently-diagnosed/where-do-i-begin/checking-blood-glucose.htmland $50 or device amortized over 2 years.
13
A disruptive solution valuable to the entire diabetes ecosystem
Great user experience to enable regular and accurate glucose measurements to drive well controlled blood glucose levels
PAYERS/EMPLOYERS
- Improved glycemic control leads to lower average glucose concentration value (A1c)1
- Lower A1C is associated with reduced health care spending2
- Improved control and time in range (TIR) is associated with decreased complications1
PATIENTS
- Improvedself-management though timely glycemic awareness
- A1C reduction when using Self Monitoring Blood Glucose and guided support4
- Improved time in range and medication dosing
PHYSICIANS
- Reimbursement, Star rating and HEDIS measures are tied to A1c reduction3
- Glucose monitoring and reporting informs:
- Medication management
- Risk stratification
- Dynamic personalized treatment plans
---
BLOODGLUCOSE LEVELS | Poorly Controlled |
Well Controlled | |
TIME/HOURS
- Nathan DM. for the DCCT/EDIC Research Group. The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: Overview. Diabetes Care Jan 2014, 37 (1)9-16.
- Fitch K, Pyenson BS, Iwasaki K. Medical Claim Cost Impact of Improved Diabetes Control for Medicare and Commercially Insured Patients with Type 2 Diabetes. Journal of Managed Care Pharmacy 2013 19:8,609-620
- Sussell, Jesse et al.Value-Based Payments and Incentives to Improve Care: A Case Study of Patients with Type 2 Diabetes in Medicare AdvantageValue in Health , Volume 20 , Issue 8 , 1216 - 1220
- Chow N, Shearer D, Aydin Plaa J, et al Blood glucoseself-monitoring and internet diabetes management on A1C outcomes in patients with type 2 diabetes BMJ Open Diabetes Research and Care 2016
Alpha MOS Proprietary | 14 |
First significant achievement in 2018: promising results for our non invasive breath analyzer platform
Conducted first large early clinical trial
> 100 patients
Plasma Blood glucose used as reference method Validated in controlled environment at leading hospital in the United Kingdom
Identified breath VOC that correlate to blood glucose levels
Same algorithm used for all patients
BG < 180mg/dl
Alpha MOS Proprietary
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* Diabetes and healthy state was determined by medical record entry. Healthy individuals with high A1c were removed from the sample.
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Support from strong scientific board combining Endocrinology, Diabetes and Behavioral expertise
Timothy Garvey, MD
Professor of Medicine in the Department of Nutrition Sciences at the University of Alabama, a state hit by obesity
Achievedinternational recognition for his
research in the metabolic, molecular, and genetic pathogenesis of insulin resistance, Type 2 Diabetes, and obesity
Steven Chen, MD
Endocrinologist physician with broad, diverse background including obesity,diabetes and academic clinical research, clinical practice, pharmaceutical clinical development (phase1-4),and medical affairs
US and global R&D experience with a specialfocus on China within emerging markets
VP, Medical Development at La Jolla Pharmaceutical Company
William Polonsky, PhD
A globally recognized leader in behavioralhealth focusing on obesity and diabetes
Associate Clinical Professor in Psychiatry at the University of California San Diego
An active researcherin the field of behavioral diabetes, he has served on the editorial boards of Diabetes Care, Diabetes Forecast, Clinical Diabetes, Diabetes Self- Management and Diabetes Health
"Non-invasive glucose monitoring has been an industry goal for many years due to its potential to improve health outcomes for people struggling with this disease. The BOYDSense technology and their early phase clinical studies show promise for making availablenon-invasiveglucose monitoring, which will be eagerly accepted and applied by patients.This technology will promote more diligent self-monitoring and more informed clinical management by health care professionals."
Alpha MOS Proprietary | 16 |
A FoodTech & MedTech company ready for growth
2017
2018 | 2019-2021 |
STRATEGIC & OPERATIONAL
COMPANY REFOCUS
Two major strategic pivots
Focus on Sensory analysis for Food & Beverage: End Of Life (EOL) old products, EOL environmental products
Move to Sensory Quality Assurance at F&B production lines since mid 2017.
Accelerated R&Dwith focus on FoodTech solutions and e-nose integration in MedTech applications
New management team (mid 2017)
New shareholders- Jolt Capital and Ambrosia Investments
TRANSITION:
FIRST ACHIEVEMENTS
FoodTech:Resetting solid foundations
Fabless company
New product design ready to scale
Software upgrade and evolution
Starting distribution network rationalization
Renewal of teams: product, software, quality, sales managers (Europe & Asia)
Strategic partnership with Coca-Cola Bottling Co. Consolidated (June)
Resumed booking growth in Q3
MedTech: Significant milestones
Platform validation through early clinical trial in United Kingdom (>100 patients)
Identification of breath VOC for diabetic test 2 new patent families filed
ACCELERATING DEVELOPMENT WITH
A CLEAR STRATEGIC ROADMAP
FoodTech: Rapidlygrowing market position in production quality control
Grow market position rapidly focusing on Top100 F&B key accounts.
Introduction of new generation of in-line products for F&B factories with global analysis reporting.
MedTech: Getting ready for product manufacturing in 2021
Fuel development towards FDA pre-submission Field trials with partners in USA (major market for diabetics)
Alpha MOS Proprietary | 17 |
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Alpha Mos SA published this content on 02 December 2019 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 02 December 2019 09:33:10 UTC