Overview

The following discussion should be read in conjunction with the Consolidated Financial Statements and notes thereto contained herein.



We are one of the largest global pharmaceutical sourcing and distribution
services companies, helping both healthcare providers and pharmaceutical and
biotech manufacturers improve patient access to products and enhance patient
care. We deliver innovative programs and services designed to increase the
effectiveness and efficiency of the pharmaceutical supply chain in both human
and animal health.

We are organized geographically based upon the products and services we provide
to our customers. At the beginning of fiscal 2022, we re-aligned our reporting
structure under two reportable segments: U.S. Healthcare Solutions and
International Healthcare Solutions. U.S. Healthcare Solutions consists of the
legacy Pharmaceutical Distribution Services reportable segment (excluding
Profarma Distribuidora de Produtos Farmacêuticos S.A.("Profarma")), MWI Animal
Health ("MWI"), Xcenda, Lash Group, and ICS 3PL. International Healthcare
Solutions consists of Alliance Healthcare, World Courier, Innomar, Profarma, and
Profarma Specialty (until it was divested in June 2022). Profarma had previously
been included in the Pharmaceutical Distribution Services reportable segment.
Our previously reported segment results have been revised to conform to our
re-aligned reporting structure.

U.S. Healthcare Solutions Segment



The U.S. Healthcare Solutions reportable segment distributes a comprehensive
offering of brand-name, specialty brand-name and generic pharmaceuticals,
over-the-counter healthcare products, home healthcare supplies and equipment,
and related services to a wide variety of healthcare providers, including acute
care hospitals and health systems, independent and chain retail pharmacies, mail
order pharmacies, medical clinics, long-term care and alternate site pharmacies,
and other customers. The U.S. Healthcare Solutions reportable segment also
provides pharmaceutical distribution (including plasma and other blood products,
injectable pharmaceuticals, vaccines, and other specialty pharmaceutical
products) and additional services to physicians who specialize in a variety of
disease states, especially oncology, and to other healthcare providers,
including hospitals and dialysis clinics. Additionally, the U.S. Healthcare
Solutions reportable segment provides data analytics, outcomes research, and
additional services for biotechnology and pharmaceutical manufacturers. The U.S.
Healthcare Solutions reportable segment also provides pharmacy management,
staffing and additional consulting services, and supply management software to a
variety of retail and institutional healthcare providers. It also provides a
full suite of integrated manufacturer services that ranges from clinical trial
support to product post-approval and commercialization support. Additionally, it
delivers packaging solutions to institutional and retail healthcare providers.
Through its animal health business, the U.S. Healthcare Solutions reportable
segment sells pharmaceuticals, vaccines, parasiticides, diagnostics, micro feed
ingredients, and various other products to customers in both the companion
animal and production animal markets. It also offers demand-creating sales force
services to manufacturers.

International Healthcare Solutions Segment



The International Healthcare Solutions reportable segment consists of businesses
that focus on international pharmaceutical wholesale and related service
operations and global commercialization services. The International Healthcare
Solutions reportable segment distributes pharmaceuticals, other healthcare
products, and related services to healthcare providers, including pharmacies,
doctors, health centers and hospitals primarily in Europe. It also is a leading
global specialty transportation and logistics provider for the biopharmaceutical
industry. In Canada, the business drives innovative partnerships with
manufacturers, providers, and pharmacies to improve product access and
efficiency throughout the healthcare supply chain.







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Recent Development

PharmaLex Acquisition

In September 2022, we entered into a definitive agreement to acquire PharmaLex
Holding GmbH ("PharmaLex"), a leading provider of specialized services for the
life sciences industry, for €1.28 billion in cash, subject to customary
adjustments. PharmaLex's services include regulatory affairs, development
consulting and scientific affairs, pharmacovigilance, and quality management and
compliance. The acquisition will advance our role as a partner of choice for
biopharmaceutical manufacturers by enhancing our global portfolio of solutions
to support manufacturer partners across the pharmaceutical development and
commercialization journey. PharmaLex will be a component of our International
Healthcare Solutions reportable segment. The acquisition is expected to close by
March 2023 and is subject to the satisfaction of customary closing conditions,
including receipt of required regulatory approvals.

Executive Summary

This executive summary provides highlights from the results of operations that follow:



•Revenue increased by $24.6 billion, or 11.5%, from the prior fiscal year,
primarily due to our June 2021 acquisition of Alliance Healthcare and revenue
growth in our U.S. Healthcare Solutions segment. Revenue in International
Healthcare Solutions increased by $15.0 billion, or 129.8%, from the prior
fiscal year primarily due to the June 2021 acquisition of Alliance Healthcare.
The U.S. Healthcare Solutions segment grew its revenue $9.6 billion, or 4.8%,
from the prior fiscal year primarily due to overall market growth principally
driven by unit volume growth and increased sales to specialty physician
practices, offset in part by a decline in sales of COVID-19 treatments
(primarily commercial treatments);

•Total gross profit increased by $1,353.1 million, or 19.5%, from the prior
fiscal year. Gross profit was favorably impacted by increases in gross profit in
International Healthcare Solutions of $1,404.7 million, or 91.1%, and U.S.
Healthcare Solutions of $425.8 million, or 8.5%, from the prior fiscal year.
Gross profit in International Healthcare Solutions increased from the prior
fiscal year primarily due to the June 2021 acquisition of Alliance Healthcare.
U.S. Healthcare Solutions' gross profit increased from the prior fiscal year
primarily due to overall revenue growth and fees earned relating to the
distribution of government-owned COVID-19 treatments. These increases were
offset in part by last-in, first-out ("LIFO") expense in comparison to a LIFO
credit in the prior year, decreases in gains from antitrust litigation
settlements, and the Turkey highly inflationary economy's unfavorable impact on
the current fiscal year;

•Total operating expenses increased by $1,341.0 million, or 29.2%, from the
prior fiscal year primarily as a result of increases in distribution, selling,
and administrative expenses and depreciation and amortization expense primarily
due to the June 2021 acquisition of Alliance Healthcare, as well as a $75.9
million goodwill impairment of our Profarma reporting unit, offset in part by
lower expense accruals related to opioid litigation settlements in the current
fiscal year;

•Total segment operating income increased by $515.2 million, or 19.5%, from the
prior fiscal year primarily due to the June 2021 acquisition of Alliance
Healthcare and 8.8% operating income growth in the U.S. Healthcare Solutions
segment; and

•Our effective tax rates were 23.7% and 30.5% for the fiscal years ended
September 30, 2022 and 2021, respectively. The effective tax rate in the fiscal
year ended September 30, 2022 was higher than the U.S. statutory rate primarily
due to U.S. state income taxes, offset in part by the benefit of non-U.S. income
taxed at rates lower than the U.S. statutory rate. Our effective tax rate in the
fiscal year ended September 30, 2021 was higher than the current year tax rate
primarily due to UK and Swiss tax reforms (see Note 4 of the Notes to
Consolidated Financial Statements).



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Results of Operations



Fiscal Year Ended September 30, 2022 compared to the Fiscal Year Ended
September 30, 2021

Revenue

                                                       Fiscal Year Ended
                                                         September 30,
       (dollars in thousands)                       2022               2021           Change
       U.S. Healthcare Solutions
       Human Health                              207,284,444       

197,777,128 4.8%

Animal Health                               4,815,758          

4,684,417 2.8%


       Total U.S. Healthcare Solutions           212,100,202        

202,461,545 4.8%

International Healthcare Solutions


       Alliance Healthcare                        21,890,402          

7,373,365 196.9%


       Other Healthcare Solutions                  4,601,271          

4,156,264 10.7%


       Total International Solutions              26,491,673         

11,529,629 129.8%


       Intersegment eliminations                      (4,869)           

(2,331)
       Revenue                                 $ 238,587,006      $ 213,988,843       11.5%


Our future revenue growth will continue to be affected by various factors, such
as industry growth trends, including drug utilization, the introduction of new,
innovative brand therapies, the likely increase in the number of generic drugs
and biosimilars that will be available over the next few years as a result of
the expiration of certain drug patents held by brand-name pharmaceutical
manufacturers and the rate of conversion from brand products to those generic
drugs and biosimilars, price inflation and price deflation, general economic
conditions in the United States and Europe, competition within the industry,
customer consolidation, changes in pharmaceutical manufacturer pricing and
distribution policies and practices, increased downward pressure on government
and other third-party reimbursement rates to our customers, changes in
government rules and regulations, foreign currency conversion rates, and the
impact of the COVID-19 pandemic.

Revenue increased by 11.5% from the prior fiscal year primarily due to our June 2021 acquisition of Alliance Healthcare and the revenue growth of our U.S. Healthcare Solutions segment.



The U.S. Healthcare Solutions segment grew its revenue by $9.6 billion, or 4.8%,
from the prior fiscal year, primarily due to overall market growth principally
driven by unit volume growth and increased sales to specialty physician
practices, offset in part by a decline in sales of COVID-19 treatments
(primarily commercial treatments).

More specifically, the increase in the U.S. Healthcare Solutions segment revenue was largely attributable to the following (in billions):

Increased sales to specialty physician practices $2.9 Decreased sales of COVID-19 treatments

                 ($2.0)
Increased sales to other customers                      $8.7


The continued decline of sales relating to COVID-19 treatments and fees earned
from the distribution of government-owned COVID-19 treatments could adversely
impact our results of operations.

Revenue in International Healthcare Solutions increased by $15.0 billion, or
129.8%, from the prior fiscal year primarily due to the June 2021 acquisition of
Alliance Healthcare.

A number of our contracts with customers, including group purchasing
organizations, are typically subject to expiration each year. We may lose a
significant customer if an existing contract with such customer expires without
being extended, renewed, or replaced. During the fiscal year ended September 30,
2022, no significant contracts expired. In January 2022, we extended our
agreement with Express Scripts through September 2026. Over the next twelve
months, there are no significant contracts scheduled to expire. Additionally,
from time to time, significant contracts may be terminated in accordance with
their terms or extended, renewed, or replaced prior to their expiration dates.
If those contracts are extended, renewed, or replaced at less favorable terms,
they may also negatively impact our revenue, results of operations, and cash
flows.

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Gross Profit

                                                           Fiscal Year Ended
                                                             September 30,
    (dollars in thousands)                               2022             2021          Change
    U.S. Healthcare Solutions                        $ 5,454,735      $ 5,028,950        8.5%
    International Healthcare Solutions                 2,947,190        

1,542,456 91.1%


    Intersegment eliminations                               (189)          

-


    Gains from antitrust litigation settlements            1,835          

168,794


    LIFO (expense) credit                                (67,171)         

203,028

Turkey highly inflationary impact                    (40,033)          

    -

    Gross profit                                     $ 8,296,367      $ 6,943,228       19.5%


Gross profit increased by $1,353.1 million, or 19.5%, from the prior fiscal
year. Gross profit in the current fiscal year was favorably impacted by
increases in gross profit in International Healthcare Solutions and U.S.
Healthcare Solutions. These increases were offset in part by LIFO expense in
comparison to a LIFO credit in the prior year, decreases in gains from antitrust
litigation settlements, and the Turkey highly inflationary economy's unfavorable
impact on the current fiscal year.

U.S. Healthcare Solutions gross profit increased by $425.8 million, or 8.5%,
from the prior fiscal year due to overall revenue growth and fees earned from
the distribution of government-owned COVID-19 treatments. As a percentage of
revenue, U.S. Healthcare Solutions gross profit margin of 2.57% in the current
fiscal year increased 9 basis points compared to the prior fiscal year primarily
due to fees earned from the distribution of government-owned COVID-19
treatments.

Gross profit in International Healthcare Solutions increased $1,404.7 million,
or 91.1%, from the prior fiscal year primarily due to the June 2021 acquisition
of Alliance Healthcare.

We recognized gains from antitrust litigation settlements with pharmaceutical
manufacturers of $1.8 million and $168.8 million in the fiscal years ended
September 30, 2022 and 2021, respectively. The gains were recorded as reductions
to Cost of Goods Sold (see Note 14 of the Notes to Consolidated Financial
Statements).

Our cost of goods sold includes a LIFO provision that is affected by
manufacturer pricing practices, which may be impacted by market and other
external influences, changes in inventory quantities, and product mix, many of
which are difficult to predict. Changes to any of the above factors may have a
material impact to our annual LIFO provision. The LIFO expense in the current
fiscal year was primarily due to lower generic pharmaceutical deflation and
inventory product mix.

We recognized an expense of $40.0 million in the fiscal year ended September 30,
2022 in Cost of Goods Sold related to the impact of Turkey highly inflationary
accounting (see Note 1 of the Notes to Consolidated Financial Statements).

Operating Expenses

                                                                       Fiscal Year Ended
                                                                         September 30,
(dollars in thousands)                                             2022                 2021                Change
Distribution, selling, and administrative                     $ 4,848,962          $ 3,594,251               34.9%
Depreciation and amortization                                     693,895              505,172               37.4%
Litigation and opioid-related expenses                            123,191              272,623
Acquisition, integration, and restructuring expenses              183,059              199,288
Goodwill impairment                                                75,936                6,373
Impairment of assets                                                4,946               11,324
Total operating expenses                                      $ 5,929,989          $ 4,589,031               29.2%


Distribution, selling, and administrative expenses increased by $1,254.7
million, or 34.9%, from the prior fiscal year. The increase from the prior
fiscal year was primarily due to the June 2021 acquisition of Alliance
Healthcare. As a percentage of revenue, distribution, selling, and
administrative expenses were 2.03% in the current fiscal year and represents a
35-basis point increase compared to the prior fiscal year primarily due to the
June 2021 acquisition of Alliance Healthcare.

Depreciation expense increased 18.3% from the prior fiscal year primarily due to
depreciation of property and equipment originating from the June 2021
acquisition of Alliance Healthcare. Amortization expense increased 72.3% from
the prior fiscal year primarily due to amortization of intangible assets
originating from the June 2021 acquisition of Alliance Healthcare.

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Litigation and opioid-related expenses in the fiscal year ended September 30,
2022 included a $36.6 million accrual related to opioid litigation settlements
and $86.6 million of legal fees in connection with opioid lawsuits and
investigations. Litigation and opioid-related expenses in the fiscal year ended
September 30, 2021 included a $147.7 million accrual related to opioid
litigation settlements and $124.9 million of legal fees in connection with
opioid lawsuits and investigations.

Acquisition, integration, and restructuring expenses in the fiscal year ended
September 30, 2022 included $119.6 million of acquisition-related deal and
integration costs primarily related to the integration of Alliance Healthcare,
$35.5 million of severance and other restructuring initiatives primarily related
to the write down of assets in connection with our office optimization plan, and
$28.0 million related to our business transformation efforts. Acquisition,
integration, and restructuring expenses in the fiscal year ended September 30,
2021 included $117.0 million of acquisition-related deal and integration costs
primarily related to the June 2021 acquisition of Alliance Healthcare, $46.1
million of severance and other restructuring initiatives primarily related to
the disposal of assets in connection with our office optimization plan, and
$36.3 million related to our business transformation efforts.

We recorded goodwill impairments of $75.9 million and $6.4 million in our
Profarma reporting unit in the fiscal years ended September 30, 2022 and 2021,
respectively (see Note 5 of the Notes to Consolidated Financial Statements).

Operating Income

                                                                            Fiscal Year Ended
                                                                              September 30,
(dollars in thousands)                                                  2022                 2021                Change
U.S. Healthcare Solutions                                          $ 2,456,972          $ 2,257,918               8.8%
International Healthcare Solutions                                     706,458              390,286               81.0%
Total segment operating income                                       3,163,430            2,648,204               19.5%

Gains from antitrust litigation settlements                              1,835              168,794
LIFO (expense) credit                                                  (67,171)             203,028
Turkey highly inflationary impact                                      (40,033)                   -
Acquisition-related intangibles amortization                          (304,551)            (176,221)
Litigation and opioid-related expenses                                (123,191)            (272,623)
Acquisition, integration, and restructuring expenses                  (183,059)            (199,288)
Goodwill impairment                                                    (75,936)              (6,373)
Impairment of assets                                                    (4,946)             (11,324)

Operating income                                                   $ 2,366,378          $ 2,354,197               0.5%


Segment operating income is evaluated before gains from antitrust litigation settlements; LIFO (expense) credit; Turkey highly inflationary impact; acquisition-related intangibles amortization; litigation and opioid-related expenses; acquisition, integration, and restructuring expenses; goodwill impairment; and impairment of assets.

U.S. Healthcare Solutions operating income increased $199.1 million, or 8.8%,
from the prior fiscal year primarily due to the increase in gross profit, as
noted above, and was offset in part by an increase in operating expenses. As a
percentage of revenue, U.S. Healthcare Solutions operating income margin was
1.16% and represented an increase of 4 basis points compared to the prior fiscal
year. The increase from the prior year fiscal year was primarily due to fees
earned from the distribution of government-owned COVID-19 treatments.

Operating income in International Healthcare Solutions increased by $316.2 million, or 81.0%, from the prior fiscal year primarily due to the June 2021 acquisition of Alliance Healthcare.

Other Income, Net



We recognized a gain of $56.2 million from the sale of non-core businesses, a
$14.4 million foreign currency loss on the remeasurement of deferred tax assets
relating to Swiss tax reform, an $11.9 million expense related to the impact of
Turkey highly inflationary accounting, and a $4.8 million gain on the
remeasurement of an equity investment in the fiscal year ended September 30,
2022.

We recorded a $64.7 million gain on the remeasurement of an equity investment, a
$14.0 million impairment of a non-customer note receivable related to a start-up
venture, and a $3.4 million foreign currency loss on the remeasurement of
deferred tax assets relating to Swiss tax reform in the fiscal year ended
September 30, 2021.

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Interest Expense, Net

Interest expense, net and the respective weighted average interest rates were as follows:



                                                                               Fiscal Year Ended September 30,
                                                                   2022                                                 2021
                                                                          Weighted Average                                  Weighted Average
(dollars in thousands)                             Amount                   Interest Rate               Amount                Interest Rate
Interest expense                             $        231,982                   2.69%                $  182,544                   2.62%
Interest income                                       (21,309)                  1.08%                    (8,470)                  0.28%
Interest expense, net                        $        210,673                                        $  174,074


Interest expense, net increased $36.6 million, or 21.0%, from the prior fiscal
year due to the issuance of our $1,525 million of 0.737% senior notes, $1,000
million of 2.700% senior notes in March 2021, and the $500 million variable-rate
term loan that was issued in June 2021, all of which were used to finance a
portion of the June 2021 acquisition of Alliance Healthcare, and the incremental
interest expense associated with Alliance Healthcare's debt in certain
countries, offset in part by the increase in interest income. The increase in
interest income was primarily due to higher investment interest rates, offset in
part by lower average invested cash balances. The increase in interest expense
as a result of the above-mentioned debt issuances was offset in part by
repayments of $250 million in September 2021 and again in March 2022 on the
above-mentioned $500 million variable-rate term loan, and payments of $500
million in June 2022 and $350 million in September 2022 on the above-mentioned
$1,525 million of 0.737% senior notes.

Our interest expense in future periods may vary significantly depending upon
changes in net borrowings, interest rates, amendments to our current borrowing
facilities, and strategic decisions to deploy our invested cash.

Income Tax Expense



  Our effective tax rates were 23.7% and 30.5% in the fiscal years ended
September 30, 2022 and 2021, respectively. Our effective tax rate in the fiscal
year ended September 30, 2022 was higher than the U.S. statutory rate primarily
due to U.S. state income taxes, offset in part by the benefit of non-U.S. income
taxed at rates lower than the U.S. statutory rate. Our effective tax rate in the
fiscal year ended September 30, 2021 was higher than the current year tax rate
primarily due to UK and Swiss tax reforms (see Note 4 of the Notes to
Consolidated Financial Statements).

Fiscal Year Ended September 30, 2021 compared to the Fiscal Year Ended September
30, 2020

Revenue

                                                      Fiscal Year Ended
                                                        September 30,
(dollars in thousands)                             2021               2020           Change
U.S. Healthcare Solutions:
Human Health                                  $ 197,777,128      $ 182,171,487        8.6%
Animal Health                                     4,684,417          4,216,462       11.1%
Total U.S. Healthcare Solutions                 202,461,545        186,387,949        8.6%
International Healthcare Solutions:
Alliance Healthcare                               7,373,365                 

-


Other Healthcare Solutions                        4,156,264          3,508,106       18.5%
Total International Healthcare Solutions         11,529,629          3,508,106       228.7%
Intersegment eliminations                            (2,331)            (2,129)
Revenue                                       $ 213,988,843      $ 189,893,926       12.7%

Revenue increased by 12.7% from the prior fiscal year primarily due to the revenue growth of our U.S. Healthcare Solutions segment and our June 2021 acquisition of Alliance Healthcare.



The U.S. Healthcare Solutions segment grew its revenue by $16.1 billion, or
8.6%, from the prior fiscal year, primarily due to increased sales of specialty
products (which generally have higher selling prices) including COVID-19
treatments, overall market growth principally driven by unit volume growth, and
growth in our animal health business.


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More specifically, the increase in the U.S. Healthcare Solutions segment revenue was largely attributable to the following (in billions):

Increased sales to Walgreens, our largest customer $1.8 Increased sales to specialty physician practices $2.3 Increased sales of COVID-19 treatments

$3.2
Increased sales to other customers                        $8.8


Revenue in International Healthcare Solutions increased by $8.0 billion, or
228.7%, from the prior fiscal year primarily due to the June 2021 acquisition of
Alliance Healthcare and due to growth in our Canadian business and our specialty
transportation and logistics business.

Gross Profit
                                                        Fiscal Year Ended
                                                           September 30
(dollars in thousands)                                2021             2020          Change
U.S. Healthcare Solutions                         $ 5,028,950      $ 4,504,040       11.7%
International Healthcare Solutions                  1,542,456          713,546       116.2%
Gains from antitrust litigation settlements           168,794            9,076
LIFO credit (expense)                                 203,028           (7,422)
PharMEDium remediation costs                                -           (7,135)
PharMEDium shutdown costs                                   -           (5,421)
New York State Opioid Stewardship Act                       -          (14,800)
Gross profit                                      $ 6,943,228      $ 5,191,884       33.7%


Gross profit increased by $1,751.3 million, or 33.7%, from the prior fiscal
year. Gross profit in fiscal 2021 was favorably impacted by increases in gross
profit in U.S. Healthcare Solutions and International Healthcare Solutions, a
LIFO credit in the current year period in comparison to a LIFO expense in the
prior year period, and an increase in gains from antitrust litigation
settlements.

U.S. Healthcare Solutions gross profit increased by $524.9 million, or 11.7%,
from the prior fiscal year due to revenue growth, including an increase in
specialty product sales. As a percentage of revenue, U.S. Healthcare Solutions'
gross profit margin of 2.48% in fiscal 2021 increased 6 basis points compared to
the prior fiscal year primarily due to an increase in specialty product sales,
including COVID-19 treatments.

Gross profit in International Healthcare Solutions increased by $828.9 million,
or 116.2%, from the prior fiscal year primarily due to the June 2021 acquisition
of Alliance Healthcare and revenue growth in our specialty transportation and
logistics business. As a percentage of revenue, gross profit margin in
International Healthcare Solutions of 13.38% in fiscal 2021 decreased from
20.34% in the prior fiscal year. The decline in gross profit margin in fiscal
2021 was primarily due to the June 2021 acquisition of Alliance Healthcare,
which has a lower gross profit margin than the other operating segments within
International Healthcare Solutions.

We recognized gains from antitrust litigation settlements with pharmaceutical
manufacturers of $168.8 million and $9.1 million in the fiscal years ended
September 30, 2021 and 2020, respectively. The gains were recorded as reductions
to Cost of Goods Sold (see Note 14 of the Notes to Consolidated Financial
Statements).

In the prior fiscal year, we incurred remediation costs in connection with the
suspended production activities at PharMEDium. We also incurred shutdown costs
in connection with permanently exiting the PharMEDium compounding business.

New York State ("NYS") enacted the Opioid Stewardship Act ("OSA"), which went
into effect on July 1, 2018. The OSA established an annual $100 million Opioid
Stewardship Fund (the "Fund") and required manufacturers, distributors, and
importers licensed in NYS to ratably source the Fund. The ratable share of the
assessment for each licensee was to be based upon opioids sold or distributed to
or within NYS. In December 2018, the OSA was ruled unconstitutional by the U.S.
District Court for the Southern District of New York. In September 2020, the
United States Court of Appeals for the Second Circuit reversed the District
Court's decision, and, as a result, we accrued $14.8 million in the fiscal year
ended September 30, 2020 related to our ratable share of the assessment.


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Operating Expenses

                                                                 Fiscal Year Ended
                                                                   September 30,
(dollars in thousands)                                       2021                 2020                  Change
Distribution, selling, and administrative               $ 3,594,251          $  2,767,217               29.9%
Depreciation and amortization                                  505,172               391,062            29.2%
Litigation and opioid-related expenses                      272,623         

6,722,346


Acquisition, integration, and restructuring                 199,288                84,961
expenses
Goodwill impairment                                              6,373                     -
Impairment of assets                                            11,324               361,652
Total operating expenses                                $ 4,589,031          $ 10,327,238              (55.6)%


Distribution, selling, and administrative expenses increased by $827.0 million,
or 29.9%, from the prior fiscal year. The increase from the prior fiscal year
was primarily due to the June 2021 acquisition of Alliance Healthcare and an
increase in payroll-related operating costs to support current and future
revenue growth. As a percentage of revenue, distribution, selling, and
administrative expenses were 1.68% in the current fiscal year and represents a
22-basis point increase compared to the prior fiscal year. The increase in
distribution, selling, and administrative expenses as a percentage of revenue
was primarily due to the June 2021 acquisition of Alliance Healthcare.

Depreciation expense increased 16.6% from the prior fiscal year primarily due to
depreciation of property and equipment originating from the June 2021
acquisition of Alliance Healthcare. Amortization expense increased 60.9% from
the prior fiscal year primarily due to amortization of intangible assets
originating from the June 2021 acquisition of Alliance Healthcare.

Litigation and opioid-related expenses in the fiscal year ended September 30,
2021 included a $147.7 million accrual related to opioid litigation settlements
and $124.9 million of legal fees in connection with opioid lawsuits and
investigations. Litigation and opioid-related expenses in the fiscal year ended
September 30, 2020 included a $6.6 billion legal accrual and $115.4 million of
legal fees in connection with opioid lawsuits and investigations.

Acquisition, integration, and restructuring expenses in the fiscal year ended
September 30, 2021 included $117.0 million of acquisition-related deal and
integration costs primarily related to the June 2021 acquisition of Alliance
Healthcare, $46.1 million of severance and other restructuring initiatives
primarily related to the disposal of assets in connection with our office
optimization plan, and $36.3 million related to our business transformation
efforts. Acquisition, integration, and restructuring expenses in the fiscal year
ended September 30, 2020 included $38.0 million related to our business
transformation efforts, $34.4 million of severance costs primarily related to
position eliminations resulting from our decision to permanently exit the
PharMEDium compounding business, and $12.6 million of acquisition-related deal
and integration costs and other restructuring initiatives.

We recorded a goodwill impairment of $6.4 million in our Profarma reporting unit
in the fiscal year ended September 30, 2021 in connection with our fiscal 2021
annual impairment test (see Note 5 of the Notes to Consolidated Financial
Statements).

We recorded a $361.7 million impairment of PharMEDium's assets in Impairment of
Assets in the fiscal year ended September 30, 2020 (see Note 1 of the Notes to
Consolidated Financial Statements).








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Operating Income (Loss)
                                                                      Fiscal Year Ended
                                                                        September 30,
(dollars in thousands)                                            2021                 2020                 Change
U.S. Healthcare Solutions                                    $ 2,257,918          $  2,020,067               11.8%
International Healthcare Solutions                               390,286               184,380              111.7%
Total segment operating income                                 2,648,204             2,204,447               20.1%

Gains from antitrust litigation settlements                      168,794                 9,076
LIFO credit (expense)                                            203,028                (7,422)
Acquisition-related intangibles amortization                    (176,221)   

(110,478)


Litigation and opioid-related expenses                          (272,623)   

(6,722,346)


Acquisition, integration, and restructuring expenses            (199,288)              (84,961)
Goodwill impairment                                               (6,373)                    -
Impairment of assets                                             (11,324)             (361,652)
PharMEDium remediation costs                                           -               (16,165)
PharMEDium shutdown costs                                              -               (43,206)
New York State Opioid Stewardship Act                                  -               (14,800)
Contingent consideration adjustment                                    -                12,153
Operating income (loss)                                      $ 2,354,197          $ (5,135,354)             145.8%


Segment operating income is evaluated before gains from antitrust litigation
settlements; LIFO credit (expense); acquisition-related intangibles
amortization; litigation and opioid-related expenses; acquisition, integration,
and restructuring expenses; goodwill impairment; impairment of assets;
PharMEDium remediation costs; PharMEDium shutdown costs; New York State Opioid
Stewardship Act; and contingent consideration adjustment.

U.S. Healthcare Solutions operating income increased by $237.9 million, or
11.8%, from the prior fiscal year primarily due to the increase in gross profit,
as noted above, and was offset in part by an increase in operating expenses. As
a percentage of revenue, U.S. Healthcare Solutions operating income margin was
1.12% and represented an increase of 4 basis points compared to the prior fiscal
year. The increase from the prior year fiscal year was primarily due to the
increase in specialty product sales, including COVID-19 treatments.

Operating income in International Healthcare Solutions increased by $205.9
million, or 111.7%, from the prior fiscal year primarily due to the June 2021
acquisition of Alliance Healthcare and an increase in operating income at World
Courier.

One of our non-wholly-owned subsidiaries, Profarma, which we consolidate based
on certain governance rights (see Note 3 of the Notes to Consolidated Financial
Statements), adjusted its previous estimate of contingent consideration in the
prior fiscal year related to the purchase price of one of its prior business
acquisitions.

Other Income, Net

We recorded a $64.7 million gain on the remeasurement of an equity investment, a
$14.0 million impairment of a non-customer note receivable related to a start-up
venture, and a $3.4 million foreign currency loss on the remeasurement of
deferred tax assets relating to Swiss tax reform in the fiscal year ended
September 30, 2021.

Interest Expense, Net

Interest expense, net and the respective weighted average interest rates were as follows:



                                                                                     Fiscal Year Ended September 30,
                                                                         2021                                                 2020
                                                                                Weighted Average                                  Weighted Average
(dollars in thousands)                                   Amount                   Interest Rate               Amount                Interest Rate
Interest expense                                   $        182,544                   2.62%                $  158,522                   3.42%
Interest income                                              (8,470)                  0.28%                   (20,639)                  0.69%
Interest expense, net                              $        174,074                                        $  137,883


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Interest expense, net increased by $36.2 million, or 26.2%, from the prior
fiscal year due to the issuance of our $1,525 million of 0.737% senior notes,
$1,000 million of 2.700% senior notes in March 2021, and the $500 million
variable-rate term loan that was issued in June 2021, all of which were used to
finance a portion of the June 2021 acquisition of Alliance Healthcare, the
incremental interest expense associated with Alliance Healthcare's debt in
certain countries, and the decrease in interest income resulting from a decrease
in investment interest rates. The increase in interest expense as a result of
the above-mentioned debt issuances was offset in part by a lower
weighted-average borrowing interest rate and the repayment of our $400 million
October 2018 term loan upon its maturity in October 2020.

Income Tax Expense (Benefit)



Our effective tax rates were 30.5% and 35.8% in the fiscal years ended September
30, 2021 and 2020, respectively. Our effective tax rate in the fiscal year ended
September 30, 2021 was higher than the U.S. statutory rate due to U.K. Tax
Reform (see Note 4 of the Notes to Consolidated Financial Statements). Our
effective tax rate in the fiscal year ended September 30, 2020 was higher than
the U.S. statutory rate due to our operating loss, the tax benefits associated
with our decision to permanently exit the PharMEDium compounding business, Swiss
Tax Reform, the CARES Act, and other discrete items and offset in part by the
tax impact of the portion of the opioid legal accrual that is not expected to be
tax deductible.

Net Income (Loss) Attributable to AmerisourceBergen Corporation and Diluted Earnings Per Share

Net income attributable to AmerisourceBergen and diluted earnings per share were significantly lower in fiscal 2020 due to the legal accrual recognized in connection with opioid lawsuits.

Critical Accounting Policies and Estimates



Critical accounting policies are those policies that involve accounting
estimates and assumptions that can have a material impact on our financial
position and results of operations and require the use of complex and subjective
estimates based upon past experience and management's judgment. Actual results
may differ from these estimates due to uncertainties inherent in such estimates.
Below are those policies applied in preparing our financial statements that
management believes are the most dependent upon the application of estimates and
assumptions. For a complete list of significant accounting policies, see Note 1
of the Notes to Consolidated Financial Statements.

Allowances for Returns and Credit Losses



Trade receivables are primarily comprised of amounts owed to us for our
pharmaceutical distribution and services activities and are presented net of an
allowance for customer sales returns and an allowance for credit losses. Our
customer sales return policy generally allows customers to return products only
if the products can be resold at full value or returned to suppliers for full
credit. We record an accrual for estimated customer sales returns at the time of
sale to the customer based upon historical customer return trends. The allowance
for returns as of September 30, 2022 and 2021 was $1,532.1 million and $1,271.6
million, respectively.

We evaluate our receivables for risk of loss by grouping our receivables with
similar risk characteristics. Expected losses are determined based on a
combination of historical loss trends, current economic conditions, and
forward-looking risk factors. Changes in these factors, among others, may lead
to adjustments in our allowance for credit losses. The calculation of the
required allowance requires judgment by management as to the impact of those and
other factors on the ultimate realization of our trade receivables. Each of our
business units performs ongoing credit evaluations of its customers' financial
condition and maintains reserves for expected credit losses and specific credit
problems when they arise. We write off balances against the reserves when
collectability is deemed remote. Each business unit performs formal, documented
reviews of the allowance at least quarterly, and our largest business units
perform such reviews monthly. There were no significant changes to this process
during the fiscal years ended September 30, 2022, 2021, and 2020, and bad debt
expense was computed in a consistent manner during these periods. The bad debt
expense for any period presented is equal to the changes in the period end
allowance for credit losses, net of write-offs, recoveries, and other
adjustments.

Bad debt expense for the fiscal years ended September 30, 2022, 2021 and 2020
was $26.1 million, $12.1 million, and $11.9 million respectively. An increase or
decrease of 0.1% in the 2022 allowance as a percentage of trade receivables
would result in an increase or decrease in the provision on accounts receivable
of approximately $18.5 million. The allowance for credit losses was $94.7
million and $85.1 million as of September 30, 2022 and 2021, respectively.

Schedule II of this Form 10-K sets forth a rollforward of allowances for returns and credit losses.


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Business Combinations



The assets acquired and liabilities assumed upon the acquisition or
consolidation of a business are recorded at fair value, with the residual of the
purchase price allocated to goodwill. We engage third-party appraisal firms to
assist management in determining the fair values of certain assets acquired and
liabilities assumed. Such valuations require management to make significant
judgments, estimates, and assumptions, especially with respect to intangible
assets. Management makes estimates of fair value based upon assumptions it
believes to be reasonable. These estimates are based upon historical experience
and information obtained from the management of the acquired companies and are
inherently uncertain. Critical estimates in valuing certain of the intangible
assets include, but are not limited to: discount rates and expected future cash
flows from and economic lives of customer relationships, trade names, existing
technology, and other intangible assets. Unanticipated events and circumstances
may occur, which may affect the accuracy or validity of such assumptions or
estimates.

Goodwill and Other Intangible Assets

Goodwill arises from acquisitions or consolidations of specific operating
companies and is assigned to the reporting unit in which a particular operating
company resides. We identify our reporting units based upon our management
reporting structure, beginning with our operating segments. We aggregate two or
more components within an operating segment that have similar economic
characteristics. We evaluate whether the components within our operating
segments have similar economic characteristics, which include the similarity of
long-term gross margins, the nature of the components' products, services, and
production processes, the types of customers and the methods by which products
or services are delivered to customers, and the components' regulatory
environment. We announced a strategic reorganization of our business and began
reporting externally under the new structure as of October 1, 2021. As of
September 30, 2022, our reporting units include Pharmaceutical Distribution
Services, U.S. Consulting Services, MWI, Alliance Healthcare, Innomar, World
Courier, and Profarma.

Goodwill and other intangible assets with indefinite lives, such as certain
trademarks and trade names, are not amortized; rather, they are tested for
impairment at least annually. For the purpose of these impairment tests, we can
elect to perform a qualitative assessment to determine if it is more likely than
not that the fair values of its reporting units and indefinite-lived intangible
assets are less than the respective carrying values of those reporting units and
indefinite-lived intangible assets, respectively. Such qualitative factors can
include, among others, industry and market conditions, overall financial
performance, and relevant entity-specific events. If we conclude based on its
qualitative assessment that it is more likely than not that the fair value of a
reporting unit is less than its carrying value, it performs a quantitative
analysis. We elected to perform a quantitative impairment assessment of goodwill
and indefinite-lived intangible assets in fiscal 2022. We elected to perform a
qualitative impairment assessment of goodwill and indefinite-lived intangible
assets in fiscal 2021, with the exception of our testing of goodwill in the
AmerisourceBergen Consulting Services (the sum of U.S. Consulting Services and
Innomar reporting units, under our prior reporting structure) and Profarma
reporting units. We elected to perform a qualitative impairment assessment of
goodwill and indefinite-lived intangible assets in fiscal 2020, with the
exception of our testing of goodwill and indefinite-lived intangibles in the MWI
and Profarma reporting units.

The quantitative goodwill impairment test requires us to compare the carrying
value of the reporting unit's net assets to the fair value of the reporting
unit. If the fair value exceeds the carrying value, no further evaluation is
required, and no impairment loss is recognized. If the carrying amount exceeds
the fair value, the difference between the carrying value and the fair value is
recorded as an impairment loss, the amount of which may not exceed the total
amount of goodwill allocated to the reporting unit.

When performing a quantitative impairment assessment, we utilize an income-based
approach to value our reporting units, with the exception of the Profarma
reporting unit, the fair value of which is based upon its publicly-traded stock
price, plus an estimated control premium. The income-based approach relies on a
discounted cash flow analysis, which considers forecasted cash flows discounted
at an appropriate discount rate, to determine the fair value of each reporting
unit. We generally believe that market participants would use a discounted cash
flow analysis to determine the fair value of our reporting units in a sale
transaction. The annual goodwill impairment test requires us to make a number of
assumptions and estimates concerning future levels of revenue growth, operating
margins, depreciation, amortization, capital expenditures, and working capital
requirements, which are based upon our long-range plan. The discount rate is an
estimate of the overall after-tax rate of return required by a market
participant whose weighted average cost of capital includes both debt and
equity, including a risk premium. While we use the best available information to
prepare our forecasted cash flows and discount rate assumptions, actual future
cash flows and/or market conditions could differ significantly resulting in
future impairment charges related to recorded goodwill balances. While there are
always changes in assumptions to reflect changing business and market
conditions, our overall methodology and the population of assumptions used have
remained unchanged.

The quantitative impairment test for indefinite-lived intangibles other than
goodwill (certain trademarks and trade names) consists of a comparison of the
fair value of the indefinite-lived intangible asset to the carrying value of the
asset as of

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the impairment testing date. We estimate the fair value of its indefinite-lived
intangibles using the relief from royalty method. We believe the relief from
royalty method is a widely used valuation technique for such assets. The fair
value derived from the relief from royalty method is measured as the discounted
cash flow savings realized from owning such indefinite-lived trademarks and
trade names and not having to pay a royalty for their use.

We completed our required annual impairment tests relating to goodwill and
indefinite-lived intangible assets in the fiscal years ended September 30, 2022,
2021, and 2020. We recorded goodwill impairments of $75.9 million and
$6.4 million in our Profarma reporting unit in connection with our fiscal 2022
and 2021 impairment tests, respectively (see Note 5 of the Notes to Consolidated
Financial Statements). No goodwill impairments were recorded in the fiscal years
ended September 30, 2020, and no indefinite-lived intangible asset impairments
were recorded in the fiscal years ended September 30, 2022, 2021, or 2020.

Finite-lived intangible assets are amortized using the straight-line method over
the estimated useful lives of the assets. We perform a recoverability assessment
of our long-lived assets when impairment indicators are present.

We recorded impairments of intangible and tangible assets totaling $361.7 million in the fiscal year ended September 30, 2020 in connection with the permanent shutdown of our compounding business.

Income Taxes



Our income tax expense, deferred tax assets and liabilities, and uncertain tax
positions reflect management's assessment of estimated future taxes to be paid
on items in the financial statements. Deferred income taxes arise from temporary
differences between financial reporting and tax reporting bases of assets and
liabilities, as well as net operating loss and tax credit carryforwards for tax
purposes.

We have established a valuation allowance against certain deferred tax assets
for which the ultimate realization of future benefits is uncertain. Expiring
carryforwards and the required valuation allowances are adjusted annually. After
application of the valuation allowances described above, we anticipate that no
limitations will apply with respect to utilization of any of the other deferred
income tax assets described above.

We prepare and file tax returns based upon our interpretation of tax laws and
regulations and record estimates based upon these judgments and interpretations.
In the normal course of business, our tax returns are subject to examination by
various taxing authorities. Such examinations may result in future tax and
interest assessments by these taxing authorities. Inherent uncertainties exist
in estimates of tax contingencies due to changes in tax law resulting from
legislation, regulation, and/or as concluded through the various jurisdictions'
tax court systems. Significant judgment is exercised in applying complex tax
laws and regulations across multiple global jurisdictions where we conduct our
operations. We recognize the tax benefit from an uncertain tax position only if
it is more likely than not that the tax position will be sustained upon
examination by the taxing authorities, including resolutions of any related
appeals or litigation processes, based upon the technical merits of the
position.

We believe that our estimates for the valuation allowances against deferred tax
assets and the amount of benefits recognized in our financial statements for
uncertain tax positions are appropriate based upon current facts and
circumstances. However, others applying reasonable judgment to the same facts
and circumstances could develop a different estimate and the amount ultimately
paid upon resolution of issues raised may differ from the amounts accrued.

The significant assumptions and estimates described in the preceding paragraphs
are important contributors to the ultimate effective tax rate in each year. If
any of our assumptions or estimates were to change, an increase or decrease in
our effective tax rate by 1% on income before income taxes would have caused
income tax expense to change by $21.8 million in the fiscal year ended September
30, 2022.

For a complete discussion of the tax impact of UK Tax Reform, Swiss Tax Reform, the legal accrual related to opioid litigation, the CARES Act, and the PharMEDium worthless stock deduction, refer to Note 4 of the Notes to Consolidated Financial Statements.

Inventories



Inventories are stated at the lower of cost or market. Cost for approximately
66% of our inventories as of September 30, 2022 and 2021 has been determined
using the LIFO method. If we had used the first-in, first-out method of
inventory valuation, which approximates current replacement cost, inventories
would have been approximately $1,383.4 million and $1,316.2 million higher than
the amounts reported as of September 30, 2022 and 2021, respectively. We
recorded LIFO expense of $67.2 million and $7.4 million in the fiscal years
ended September 30, 2022 and 2020, respectively. We recorded a LIFO credit of
$203.0 million in the fiscal year ended September 30, 2021. The annual LIFO
provision is affected by manufacturer pricing practices, which may be impacted
by market and other external influences, changes in inventory

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quantities, and product mix, many of which are difficult to predict. Changes to any of the above factors can have a material impact to our annual LIFO provision.

Loss Contingencies



In the ordinary course of business, we become involved in lawsuits,
administrative proceedings, government subpoenas, government investigations,
stockholder demands, and other disputes, including antitrust, commercial,
product liability, intellectual property, regulatory, employment discrimination,
and other matters. Significant damages or penalties may be sought in some
matters, and some matters may require years to resolve. We record a liability
when it is both probable that a loss has been incurred and the amount can be
reasonably estimated. We also perform an assessment of the materiality of loss
contingencies where a loss is either not probable or it is reasonably possible
that a loss could be incurred in excess of amounts accrued. If a loss or an
additional loss has at least a reasonable possibility of occurring and the
impact on the financial statements would be material, we provide disclosure of
the loss contingency and whether a reasonable estimate of the loss or the range
of the loss can made in the footnotes to our financial statements. We review all
contingencies at least quarterly to determine whether the likelihood of loss has
changed and to assess whether a reasonable estimate of the loss or the range of
the loss can be made. Among the loss contingencies we considered in accordance
with the foregoing in connection with the preparation of the accompanying
financial statements were the opioid matters described in Note 13 of the Notes
to Consolidated Financial Statements.

Liquidity and Capital Resources



Our operating results have generated cash flows, which, together with
availability under our debt agreements and credit terms from suppliers, have
provided sufficient capital resources to finance working capital and cash
operating requirements, and to fund capital expenditures, acquisitions,
repayment of debt, the payment of interest on outstanding debt, dividends, and
purchases of shares of our common stock.

 Our primary ongoing cash requirements will be to finance working capital, fund
the repayment of debt, fund the payment of interest on debt, fund the payment of
dividends, fund purchases of our common stock, finance acquisitions, and fund
capital expenditures and routine growth and expansion through new business
opportunities. Future cash flows from operations and borrowings are expected to
be sufficient to fund our ongoing cash requirements, including the opioid
litigation payments that will be made over 18 years (see below).

Cash Flows



As of September 30, 2022 and 2021, our cash and cash equivalents held by foreign
subsidiaries were $688.4 million and $725.4 million, respectively. We have the
ability to repatriate the majority of our cash and cash equivalents held by our
foreign subsidiaries without incurring significant additional taxes upon
repatriation.

We have increased seasonal needs related to our inventory build during the
December and March quarters that, depending on our cash balance, may require the
use of our credit facilities to fund short-term capital needs. Our cash balances
in the fiscal years ended September 30, 2022 and 2021 were supplemented by
intra-period credit facility borrowings to cover short-term working capital
needs. The largest amount of intra-period borrowings under our revolving and
securitization credit facilities that was outstanding at any one time during the
fiscal years ended September 30, 2022 and 2021 was $590.0 million and $637.7
million, respectively. We had $4,435.9 million, $4,730.5 million, and $117.4
million of cumulative intra-period borrowings that were repaid under our credit
facilities during the fiscal years ended September 30, 2022, 2021, and 2020,
respectively.

During the fiscal years ended September 30, 2022 and 2021, our operating activities provided cash of $2,703.1 million and $2,666.6 million, respectively. Cash provided by operations in the fiscal year ended September 30, 2022 was principally the result of the following:

•An increase in accounts payable of $3,320.7 million primarily due to the increase in our inventory balances and the timing of scheduled payments to our suppliers;

•Net income of $1,666.5 million;



•Positive non-cash items of $1,176.2 million, which is primarily comprised of
depreciation expense of $390.6 million, amortization expense of $319.2 million,
and the provision for deferred income taxes of $196.2 million, offset in part
by:

•An increase in accounts receivable of $1,659.5 million primarily due to an increase in sales and the timing of scheduled payments from our customers; •An increase in inventories of $665.4 million to support the increase in business volume;


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•A decrease in long-term accrued litigation liability of $500.2 million due to
opioid litigation settlement payments;
•A decrease in accrued expenses of $457.2 million; and
•A decrease in income taxes payable and other liabilities of $330.1 million.

During the fiscal years ended September 30, 2021 and 2020, our operating activities provided cash of $2,666.6 million and $2,207.0 million, respectively. Cash provided by operations in the fiscal year ended September 30, 2021 was principally the result of the following:



•An increase in accounts payable of $2,049.2 million primarily driven by the
increase in inventories and the timing of scheduled payments to our suppliers;
•Net income of $1,544.6 million;
•Net positive non-cash items totaling $754.7 million, which is primarily
comprised of the provision for deferred income taxes of $334.9 million,
depreciation expense of $326.7 million, amortization expense of $188.1 million,
and a LIFO credit of $203.0 million, offset in part by:
•An increase in inventories of $1,116.3 million to support the increase in
business volume; and
•An increase in accounts receivable of $930.1 million primarily due to our
revenue growth and the timing of payments from our customers.

We use days sales outstanding, days inventory on hand, and days payable
outstanding to evaluate our working capital performance. The below financial
metrics are calculated based upon a quarterly average and can be impacted by the
timing of cash receipts and disbursements, which can vary significantly
depending upon the day of the week in which the month ends.

                                                 Fiscal Year Ended 

September 30,


                                          2022                    2021               2020
         Days sales outstanding           27.7                    26.2               24.7
         Days inventory on hand           28.3                    28.6               28.7
         Days payable outstanding         60.0                    58.3               57.6


Our cash flows from operating activities can vary significantly from period to
period based upon fluctuations in our period-end working capital account
balances. Additionally, any changes to payment terms with a significant customer
or manufacturer supplier could have a material impact to our cash flows from
operations. The acquisition of Alliance Healthcare increased our days sales
outstanding and days payable outstanding as it has longer payment terms with
customers and manufacturers. Operating cash flows during the fiscal year ended
September 30, 2022 included $219.8 million of interest payments and $244.4
million of income tax payments, net of refunds. Operating cash flows during the
fiscal year ended September 30, 2021 included $170.9 million of interest
payments and $93.5 million of income tax payments, net of refunds. Operating
cash flows during the fiscal year ended September 30, 2020 included $150.7
million of interest payments and $139.4 million of income tax payments, net of
refunds.

Capital expenditures in the fiscal years ended September 30, 2022, 2021, and
2020 were $496.3 million, $438.2 million, and $369.7 million, respectively.
Significant capital expenditures in fiscal 2022 included investments in various
technology initiatives, including technology initiatives at Alliance Healthcare.
Significant capital expenditures in fiscal 2021 and 2020 included costs
associated with facility expansions, and various technology initiatives,
including costs related to enhancing and upgrading our primary information
technology operating systems.

We currently expect to spend approximately $500 million for capital expenditures
during fiscal 2023. Larger 2023 capital expenditures will include investments
relating to various technology initiatives, including technology investments at
Alliance Healthcare and those required to comply with new regulatory
requirements.

In addition to capital expenditures, net cash used in investing activities in
the fiscal year ended September 30, 2022 included $133.8 million of cash to
acquire companies, including $60.0 million that was paid to settle accrued
consideration related to the Alliance Healthcare acquisition (see Note 2 of the
Notes to Consolidated Financial Statements), and was offset in part by $272.6
million in proceeds from the sale of non-core businesses.

In addition to capital expenditures, net cash used in investing activities in
the fiscal year ended 2021 included $5,563.0 million of cash to acquire
companies, which principally related to the June 2021 acquisition of Alliance
Healthcare, net of cash acquired, and $162.6 million for equity investments.

Net cash used in financing activities in the fiscal year ended September 30,
2022 principally resulted from an $850 million repayment of our 0.737% senior
notes that mature in 2023, the repayment of our $250 million term loan, $391.7
million in cash dividends paid on our common stock, and $483.7 million in
purchases of our common stock.

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Net cash provided by financing activities in the fiscal year ended September 30,
2021 principally resulted from the issuance of senior notes and the February
2021 Term Loan (see above) and $198.8 million of exercises of stock options,
offset in part by $650 million of repayments of our term loans, $366.6 million
in cash dividends paid on our common stock, and $82.2 million in purchases of
our common stock.

Net cash used in financing activities in the fiscal year ended September 30,
2020 principally related to $420.4 million in purchases of our common stock and
$343.6 million in cash dividends paid on our common stock.

Debt and Credit Facility Availability



The following illustrates our debt structure as of September 30, 2022, including
availability under the multi-currency revolving credit facility, the receivables
securitization facility, the revolving credit note, the money market facility,
Alliance Healthcare debt, and the overdraft facility:

                                                            Outstanding       Additional
    (in thousands)                                            Balance        Availability
    Fixed-Rate Debt:

    0.737% senior notes due 2023                           $   672,736

$ -

$500,000, 3.400% senior notes due 2024                     499,195                 -
    $500,000, 3.250% senior notes due 2025                     498,347                 -
    $750,000, 3.450% senior notes due 2027                     745,622                 -
    $500,000, 2.800% senior notes due 2030                     495,348                 -
    $1,000,000, 2.700% senior notes due 2031                   990,480                 -
    $500,000, 4.250% senior notes due 2045                     495,162                 -
    $500,000, 4.300% senior notes due 2047                     493,288     

           -
    Nonrecourse debt                                            66,539                 -
    Total fixed-rate debt                                    4,956,717                 -

    Variable-Rate Debt:
    Revolving credit note                                            -            75,000
    Money market facility                                            -           100,000

    Receivables securitization facility due 2025               350,000     

1,100,000


    Overdraft facility due 2024 (£10,000)                            -    

11,169


    Multi-currency revolving credit facility due 2027                -     

   2,400,000
    Alliance Healthcare debt                                   336,886           109,624
    Nonrecourse debt                                            59,230                 -
    Total variable-rate debt                                   746,116         3,795,793
    Total debt                                             $ 5,702,833      $  3,795,793


In May 2020, we issued $500 million of 2.80% senior notes due May 15, 2030 (the
"2030 Notes"). The 2030 Notes were sold at 99.71% of the principal amount and
have an effective yield of 2.81%. Interest on the 2030 Notes is payable
semi-annually in arrears and commenced on November 15, 2020.

We used the proceeds from the 2030 Notes to finance the early retirement of the $500 million of 3.50% senior notes that were due in 2021 and made a $21.4 million prepayment premium in connection with this early retirement.



In March 2021, we issued $1,525 million of 0.737% senior notes due March 15,
2023 (the "2023 Notes"). The 2023 Notes were sold at 100.00% of the principal
amount. Interest on the 2023 Notes is payable semi-annually in arrears,
commencing on September 15, 2021. In March 2021, we issued $1,000 million of
2.700% senior notes due March 15, 2031 (the "2031 Notes"). The 2031 Notes were
sold at 99.79% of the principal amount and have an effective yield of 2.706%.
Interest on the 2031 Notes is payable semi-annually in arrears and commenced on
September 15, 2021. The 2023 Notes and 2031 Notes rank pari passu to our other
senior notes, the Multi-Currency Revolving Credit Facility, the Revolving Credit
Note, the Overdraft Facility, and the Money Market Facility. We used the
proceeds from the 2023 Notes and 2031 Notes to finance a portion of the June
2021 Alliance Healthcare acquisition.

In fiscal 2022, we elected to repay $850 million of the 2023 Notes due in March 2023.



In addition to the 2023 Notes, the 2030 Notes, and the 2031 Notes, we have $500
million of 3.40% senior notes due May 15, 2024, $500 million of 3.25% senior
notes due March 1, 2025, $750 million of 3.45% senior notes due December 15,
2027, $500 million of 4.25% senior notes due March 1, 2045, and $500 million of
4.300% senior notes due December 15, 2047 (collectively, the "Notes"). Interest
on the Notes is payable semiannually in arrears.

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We have a $2.4 billion multi-currency senior unsecured revolving credit facility
("Multi-Currency Revolving Credit Facility"), which was scheduled to expire in
November 2026, with a syndicate of lenders. In October 2022, we amended and
restated the Multi-Currency Revolving Credit Facility to extend the expiration
to October 2027 and to make changes to effect a transition from the LIBOR
interest rate benchmark to Term SOFR. Interest on borrowings under the
Multi-Currency Revolving Credit Facility accrues at specified rates based upon
our debt rating and ranges from 80.5 basis points to 122.5 basis points over
SOFR/EURIBOR/CDOR/RFR, as applicable (101.5 basis points over
CDOR/LIBOR/EURIBOR/Bankers Acceptance Stamping Fee as of September 30, 2022) and
from 0 basis points to 22.5 basis points over the alternate base rate and
Canadian prime rate, as applicable. We pay facility fees to maintain the
availability under the Multi-Currency Revolving Credit Facility at specified
rates based upon our debt rating, ranging from 7 basis points to 15 basis
points, annually, of the total commitment (11 basis points as of September 30,
2022). We may choose to repay or reduce our commitments under the Multi-Currency
Revolving Credit Facility at any time. The Multi-Currency Revolving Credit
Facility contains covenants, including compliance with a financial leverage
ratio test, as well as others that impose limitations on, among other things,
indebtedness of subsidiaries and asset sales, with which we were compliant as of
September 30, 2022.

We have a commercial paper program whereby we may from time to time issue
short-term promissory notes in an aggregate amount of up to $2.4 billion at any
one time. Amounts available under the program may be borrowed, repaid, and
re-borrowed from time to time. The maturities on the notes will vary, but may
not exceed 365 days from the date of issuance. The notes will bear interest, if
interest bearing, or will be sold at a discount from their face amounts. The
commercial paper program does not increase our borrowing capacity as it is fully
backed by our Multi-Currency Revolving Credit Facility. There were no borrowings
outstanding under our commercial paper program as of September 30, 2022 and
2021.

We have a $1,450 million receivables securitization facility ("Receivables
Securitization Facility"), which was scheduled to expire in November 2024. In
October 2022, we amended the Receivables Securitization Facility ("Receivables
Amendment") to extend the expiration for an additional one year until October
2025. In addition, the Receivables Amendment made changes to (i) substitute Term
SOFR for LIBOR as a benchmark and establish procedures to choose a new benchmark
if Term SOFR becomes unavailable, (ii) provide for the return of erroneous
payments, if any, by purchasers, (iii) update provisions regarding compliance
with sanctions and anti-money laundering laws, and (iv) implement certain other
technical amendments. We have available to us an accordion feature whereby the
commitment on the Receivables Securitization Facility may be increased by up to
$250 million, subject to lender approval, for seasonal needs during the December
and March quarters. Interest rates are based upon prevailing market rates for
short-term commercial paper or 30-day Term SOFR plus a program fee. We pay a
customary unused fee at prevailing market rates, annually, to maintain the
availability under the Receivables Securitization Facility.

In connection with the Receivables Securitization Facility, AmerisourceBergen
Drug Corporation and a specialty distribution subsidiary sell on a revolving
basis certain accounts receivable to Amerisource Receivables Financial
Corporation, a wholly-owned special purpose entity, which in turn sells a
percentage ownership interest in the receivables to financial institutions and
commercial paper conduits sponsored by financial institutions. AmerisourceBergen
Drug Corporation is the servicer of the accounts receivable under the
Receivables Securitization Facility. As sold receivables are collected,
additional receivables may be sold up to the maximum amount available under the
facility. We use the facility as a financing vehicle because it generally offers
an attractive interest rate relative to other financing sources. We securitize
our trade accounts, which are generally non-interest bearing, in transactions
that are accounted for as borrowings. The Receivables Securitization Facility
contains similar covenants to the Multi-Currency Revolving Credit Facility, with
which we were compliant as of September 30, 2022.

We have an uncommitted, unsecured line of credit available to us pursuant to a
revolving credit note ("Revolving Credit Note"). The Revolving Credit Note
provides us with the ability to request short-term unsecured revolving credit
loans from time to time in a principal amount not to exceed $75 million. The
Revolving Credit Note may be decreased or terminated by the bank or us at any
time without prior notice. We also have a £10 million uncommitted U.K. overdraft
facility ("Overdraft Facility"), which expires in February 2024, to fund
short-term normal trading cycle fluctuations related to our MWI Animal Health
business. We have an uncommitted, unsecured line of credit available to us
pursuant to a money market credit agreement ("Money Market Facility"). The Money
Market Facility provides us with the ability to request short-term unsecured
revolving credit loans from time to time in a principal amount not to exceed
$100 million. The Money Market Facility may be decreased or terminated by the
bank or us at any time without prior notice.

Our $400 million Term Loan matured and was repaid in October 2020.



In February 2021, we entered into a $1.0 billion variable-rate term loan
("February 2021 Term Loan"), which was available to be drawn on the closing date
of the acquisition of Alliance Healthcare. In April 2021, we reduced our
commitment under the February 2021 Term Loan to $500 million. In June 2021, we
borrowed $500 million under the February 2021 Term Loan to finance a portion of
the June 2021 Alliance Healthcare acquisition. We elected to make principal
payments of $250 million in September 2021 and again in March 2022 to repay the
loan that was scheduled to mature in 2023.

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Alliance Healthcare debt is comprised of uncommitted revolving credit facilities
in various currencies with various rates. A majority of the outstanding
borrowings were held in Egypt (which is 50% owned) as of September 30, 2022 and
2021. These facilities are used to fund its working capital needs.

Nonrecourse debt is comprised of short-term and long-term debt belonging to the Brazil subsidiaries and is repaid solely from the Brazil subsidiaries' cash flows and such debt agreements provide that the repayment of the loans (and interest thereon) is secured solely by the capital stock, physical assets, contracts, and cash flows of the Brazil subsidiaries.

Share Purchase Programs and Dividends



  In October 2018, our board of directors authorized a share repurchase program
allowing us to purchase up to $1.0 billion of our shares of common stock,
subject to market conditions. During the fiscal year ended September 30, 2019,
we purchased $538.9 million of our common stock under this program, which
included $14.8 million of September 2019 purchases that cash settled in October
2019. During the fiscal year ended September 30, 2020, we purchased $405.6
million of our common stock, which excluded $14.8 million of September 2019
purchases that cash settled in October 2019. During the fiscal year ended
September 30, 2021, we purchased $55.5 million of our common stock to complete
our authorization under this program.

In May 2020, our board of directors authorized a share repurchase program
allowing us to purchase up to $500 million of our outstanding shares of common
stock, subject to market conditions. During the fiscal year ended September 30,
2021, we purchased $26.6 million of our common stock. During the fiscal year
ended September 30, 2022, we purchased $473.4 million of our common stock to
complete our authorization under this program.

In May 2022, the Company's board of directors authorized a new share repurchase
program allowing the Company to purchase up to $1.0 billion of its outstanding
shares of common stock, subject to market conditions. During the fiscal year
ended September 30, 2022, we purchased $38.7 million of our common stock, which
included $28.4 million of September 2022 purchases that cash settled in October
2022. As of September 30, 2022, we had $961.3 million of availability remaining
under this program. In October 2022, under this program, we purchased
0.6 million shares of our common stock for $78.8 million. In November 2022,
under this program, we purchased 3.2 million shares of our common stock from WBA
for $500.0 million.

Our board of directors approved the following quarterly dividend increases:



                                         Dividend Increases
                                               Per Share
               Date                   New Rate          Old Rate          % Increase
               January 2020            $0.420            $0.400               5%
               November 2020           $0.440            $0.420               5%
               November 2021           $0.460            $0.440               5%
               November 2022           $0.485            $0.460               5%


We anticipate that we will continue to pay quarterly cash dividends in the
future. However, the payment and amount of future dividends remain within the
discretion of our board of directors and will depend upon our future earnings,
financial condition, capital requirements, and other factors.

Commitments and Obligations



As discussed in Note 13 of the Notes to Consolidated Financial Statements, on
July 21, 2021, it was announced that we and the two other national
pharmaceutical distributors had negotiated a comprehensive opioid settlement
agreement. The comprehensive settlement agreement became effective on April 2,
2022, and as of September 30, 2022, it included 48 of 49 eligible states (the
"Settling States") as well as 99% by population of the eligible political
subdivisions in the Settling States. Pursuant to the comprehensive settlement
agreement and related agreements with Settling States, we will pay up to
approximately $6.4 billion over 18 years. Our estimated liability related to the
State of Alabama (with whom we have not reached a settlement agreement), as well
as other opioid-related litigation for which we have reached settlement
agreements is approximately $0.4 billion. Net of $0.8 billion of payments made
through September 30, 2022, we have a $6.0 billion liability on our Consolidated
Balance Sheet as of September 30, 2022 for litigation relating to our
comprehensive opioid settlement as well as other opioid-related litigation. The
payment of the aforementioned litigation liability has not and is not expected
to have an impact on our ability to pay dividends.

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The following is a summary of our contractual obligations for future principal
and interest payments on our debt, minimum rental payments on our noncancellable
operating leases, and minimum payments on our other commitments as of
September 30, 2022:

                                              Debt, Including
                                                  Interest             Operating               Other
Payments Due by Period (in thousands)             Payments               Leases             Commitments             Total
Within 1 year                                 $   1,245,995          $   192,031          $    123,771          $ 1,561,797
1-3 years                                         1,688,379              333,213               137,111            2,158,703
4-5 years                                           235,886              257,090                57,788              550,764
After 5 years                                     4,215,090              456,276                     -            4,671,366
Total                                         $   7,385,350          $ 1,238,610          $    318,670          $ 8,942,630


  The 2017 Tax Act required a one-time transition tax to be recognized on
historical foreign earnings and profits. We expect to pay $157.1 million, net of
overpayments and tax credits, related to this transition tax, as of
September 30, 2022, which is payable in installments over a six-year period that
commenced in January 2021. The transition tax commitment is included in "Other
Commitments" in the above table.

Our liability for uncertain tax positions was $553.2 million (including interest
and penalties) as of September 30, 2022. This liability represents an estimate
of tax positions that we have taken in our tax returns which may ultimately not
be sustained upon examination by taxing authorities. Since the amount and timing
of any future cash settlements cannot be predicted with reasonable certainty,
the estimated liability has been excluded from the above contractual obligations
table. Our liability for uncertain tax positions as of September 30, 2022
primarily includes an uncertain tax benefit related to the $6.8 billion legal
accrual for litigation related to the distribution of prescription opioid pain
medications, as disclosed in Note 13 of the Notes to Consolidated Financial
Statements.

Market Risk



We have exposure to foreign currency and exchange rate risk from our non-U.S.
operations. Our largest exposure to foreign exchange rates exists primarily with
the U.K. Pound Sterling, the Euro, the Turkish Lira, the Egyptian Pound, the
Brazilian Real, and the Canadian Dollar. During the quarter ended March 31,
2022, Turkey became a highly inflationary economy, as defined under U.S. GAAP
(see Note 1 of the Notes to Consolidated Financial Statements). Also, with the
June 2021 acquisition of Alliance Healthcare, our foreign currency and exchange
rate risk increased; therefore, we now use forward contracts to hedge against
the foreign currency exchange rate impact on certain intercompany receivable and
payable balances. We may use derivative instruments to hedge our foreign
currency exposure, but not for speculative or trading purposes. Revenue from our
foreign operations during the fiscal year ended September 30, 2022 was
approximately 11% of our consolidated revenue.

We have market risk exposure to interest rate fluctuations relating to our debt.
We manage interest rate risk by using a combination of fixed-rate and
variable-rate debt. The amount of variable-rate debt fluctuates during the year
based on our working capital requirements. We had $746.1 million of
variable-rate debt outstanding as of September 30, 2022. We periodically
evaluate financial instruments to manage our exposure to fixed and variable
interest rates. However, there are no assurances that such instruments will be
available in the combinations we want and/or on terms acceptable to us. There
were no such financial instruments in effect as of September 30, 2022.

We also have market risk exposure to interest rate fluctuations relating to our
cash and cash equivalents. We had $3,388.2 million in cash and cash equivalents
as of September 30, 2022. The unfavorable impact of a hypothetical decrease in
interest rates on cash and cash equivalents would be partially offset by the
favorable impact of such a decrease on variable-rate debt. For every
$100 million of cash invested that is in excess of variable-rate debt, a
10-basis point decrease in interest rates would increase our annual net interest
expense by $0.1 million.

Deterioration of general economic conditions, among other factors, could
adversely affect the number of prescriptions that are filled and the amount of
pharmaceutical products purchased by consumers and, therefore, could reduce
purchases by our customers. In addition, volatility in financial markets may
also negatively impact our customers' ability to obtain credit to finance their
businesses on acceptable terms. Reduced purchases by our customers or changes in
the ability of our customers to remit payments to us could adversely affect our
revenue growth, our profitability, and our cash flow from operations.

Recent elevated levels of inflation in the global and U.S. economies have not
had a significant impact on our results of operations. If elevated levels of
inflation persist or increase, our operations and financial results could be
adversely affected, particularly in certain global markets.

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We have risks from other geopolitical trends and events, such as the Russia-Ukraine war. Although the long-term implications of Russia's invasion of Ukraine are difficult to predict at this time, the financial impact of the conflict in fiscal 2022 has not been material.

ITEM 7A. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

The Company's most significant market risks are the effects of changing interest rates, foreign currency risk, and the changes in the price of the Company's common stock. See discussion under the heading "Market Risk," which is incorporated by reference herein.


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