Amgen announced the appointment of Esteban Santos as executive vice president, Operations, effective July 25, 2016, reporting to Robert A. Bradway, chairman and chief executive officer. Santos will be responsible for Amgen's Operations organization which encompasses manufacturing, process development, quality, engineering and global supply chain. He will succeed Madhavan (Madhu) Balachandran, 65, who is retiring at the end of the year. Santos, 48, has been senior vice president, Manufacturing with responsibilities for worldwide product supply since 2013. He joined Amgen in 2007 and previously held various leadership roles, including vice president, Drug Product; vice president, Site Operations; vice president, Manufacturing; and vice president, Engineering. Before joining Amgen, Santos was site general manager for the Johnson & Johnson (J&J) Cordis operation in Puerto Rico. Succeeding Santos as senior vice president, Manufacturing will be Robert Maroney, who is currently vice president, Site Operations at Amgen Manufacturing Ltd. in Juncos, Puerto Rico.