Details for the abstract selected for publication are as follows:
Title: Pre-clinical anti-tumor activity of small-molecule oral PD-L1 checkpoint inhibitors
Abstract Number: e14558
Authors: Emily P Thi, Andrew G Cole,
Session: Publication Only –
The abstract is available on ASCO’s website at //asco.org/abstracts.
About PD-L1
Immune checkpoints such as PD-1/PD-L1 play an important role in the induction and maintenance of immune tolerance and in T-cell activation. We have identified a class of small-molecule oral PD-L1 inhibitors that we believe will allow for controlled checkpoint blockade, enable oral dosing, and mitigate systemic safety issues typically seen with checkpoint antibody therapies.
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Email: ir@arbutusbio.com
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Email: lcaperelli@arbutusbio.com
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