Fourth Quarter 2020 and Recent Highlights
Announced FDA clearance of Investigational New Drug (IND) application to initiate Phase 1b/2a SWARM-P.a. clinical trial of lead candidate AP-PA02 in Pseudomonas aeruginosa infections
Appointed biotechnology finance veteran
Hired
Subsequent to the end of the fourth quarter 2020, the Company raised gross proceeds of
'During the fourth quarter and subsequent period, we made great progress across all aspects of our business,' stated
'Looking ahead, in addition to initiating a Phase 1b/2 trial of AP-SA02 in Staphylococcus aureus bacteremia infections, we are also working toward the initiation of additional clinical trials assessing phage-based candidates in difficult to treat pathogens. Indications we are exploring include non-cystic fibrosis bronchiectasis, pneumonia and prosthetic joint infection. With an efficient clinical plan targeting several distinct indications, we believe we can play a key role in the advancement of phage therapy as a viable answer to the rise of antimicrobial resistance,'
Anticipated 2021 and 2022 Milestones
Complete the single ascending dose (SAD) cohort of the SWARM-P.a. Phase 1b/2a clinical trial evaluating AP-PA02 as a potential treatment for Pseudomonas aeruginosa infections in the coming months
Initiate and complete the multiple ascending dose (MAD) cohort of SWARM-P.a. trial in late 2021/early 2022
Initiate a Phase 1b/2 clinical trial evaluating AP-SA02 as a potential treatment for Staphylococcus aureus bacteremia
Initiate at least one additional clinical trial using either of its two lead phage product candidates or slightly altered mixtures of phage products in an additional indication
About
Armata is a clinical-stage biotechnology company focused on the development of pathogen-specific bacteriophage therapeutics for the treatment of antibiotic-resistant and difficult-to-treat bacterial infections using its proprietary bacteriophage-based technology. Armata is developing and advancing a broad pipeline of natural and synthetic phage candidates, including clinical candidates for Pseudomonas aeruginosa, Staphylococcus aureus, and other pathogens. In addition, in collaboration with Merck, known as MSD outside of
Forward Looking Statements
This communication contains 'forward-looking' statements, including, without limitation, statements related to the use of proceeds from the securities offering, Armata's bacteriophage development programs, Armata's ability to meet expected milestones, Armata's ability to be a leader in the development of phage-based therapeutics, and statements related to the timing and results of clinical trials, including the anticipated initiation of clinical trials of AP-PA02 and AP-SA02, Armata's ability to develop new products based on bacteriophages and synthetic phages, and Armata's expectations for performance of Armata's therapeutic candidates based on Armata's recent nonclinical work. Any statements contained in this communication that are not statements of historical fact may be deemed to be forward-looking statements. These forward-looking statements are based upon Armata's current expectations. Forward-looking statements involve risks and uncertainties. Armata's actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of these risks and uncertainties, which include, without limitation, risks related to the ability of Armata's lead clinical candidates, AP-PA02 and AP-SA02, to be more effective than previous candidates; Armata's ability to expedite development of AP-PA02; Armata's ability to advance its preclinical and clinical programs and the uncertain and time-consuming regulatory approval process; Armata's ability to develop products based on bacteriophages and synthetic phages to kill bacterial pathogens; the Company's expected market opportunity for its products; Armata's ability to sufficiently fund its operations as expected, including obtaining additional funding as needed and any delays or adverse events within, or outside of, Armata's control, caused by the recent outbreak of COVID-19. Additional risks and uncertainties relating to Armata and its business can be found under the caption 'Risk Factors' and elsewhere in Armata's filings and reports with the
Armata expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in Armata's expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based.
Contact:
Tel: 858-800-2492
Email: ir@armatapharma.com
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