AstraZeneca : Transaction by Person Discharging Managerial Responsibilities (Form 6-K)

Transaction by Person Discharging Managerial Responsibilities

AstraZeneca PLC (the Company) announced that on 14 May 2021, Pascal Soriot, Chief Executive Officer, was granted an award of the Company's ordinary shares of $0.25 each (Ordinary Shares) under the terms of the AstraZeneca Performance Share Plan (AZPSP), as detailed in the table below.

This award forms part of the AZPSP award granted to Mr Soriot on 5 March 2021. As described in AstraZeneca's 2020 Directors' Remuneration Report, it has been made in accordance with the Directors' Remuneration Policy and amended rules of the AZPSP approved by shareholders at the Company's 2021 Annual General Meeting.

PDMR	Ordinary Shares granted under the AZPSP	Award price per Ordinary Share
Pascal Soriot	19,391	£68.44

The award is subject to a combination of performance measures focused on scientific, commercial, financial and ESG performance. Further details of the performance measures attached to the AZPSP award can be found in AstraZeneca's 2020 Directors' Remuneration Report, which is contained within the AstraZeneca Annual Report and Form 20-F Information 2020 (available on the Company's website at www.astrazeneca.com/annualreport2020).

The performance measures will be assessed over a three-year performance period (1 January 2021 to 31 December 2023). The Ordinary Shares granted under the AZPSP are subject to a two-year holding period following the performance period, and are due to vest on the fifth anniversary of grant.

1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	Pascal Soriot
2	Reason for the notification
a)	Position/status	Chief Executive Officer
b)	Initial notification /Amendment	Initial notification
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	AstraZeneca PLC
b)	LEI	PY6ZZQWO2IZFZC3IOL08
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	Ordinary Shares of US$0.25 each in AstraZeneca PLC GB0009895292
b)	Nature of the transaction	Grant of a share award under the AstraZeneca Performance Share Plan
c)	Price(s) and volume(s)	Price(s)	Volume(s)
£68.44	19,391
d)	Aggregated information - Aggregated volume - Price	Not applicable - single transaction
e)	Date of the transaction	14 May 2021
f)	Place of the transaction	Outside a trading venue

AstraZeneca

AstraZeneca (LSE/STO/Nasdaq: AZN) is a global, science-led biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines in Oncology and BioPharmaceuticals, including Cardiovascular, Renal & Metabolism, and Respiratory & Immunology. Based in Cambridge, UK, AstraZeneca operates in over 100 countries, and its innovative medicines are used by millions of patients worldwide. Please visit astrazeneca.com and follow the Company on Twitter @AstraZeneca.

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Adrian Kemp

Company Secretary

AstraZeneca PLC