Berkeley Lights, Inc. announced the launch of the Opto® Memory B Discovery Rabbit workflow, expanding the diversity of antibodies customers can discover on the Beacon® platform. The new workflow enables rapid, automated generation of antigen-specific, functional monoclonal antibodies from rabbit memory B cells, building on prior workflows that used mouse plasma B cell samples. This workflow broadens Berkeley Lights' market opportunity beyond mouse workflows, enabling discovery of high-value rabbit antibodies that are well-suited for therapeutics, diagnostics and research reagents.

While there are currently no robust markers to enrich rabbit plasma B cells, rabbit memory B cells can be readily obtained from blood and easier to source and handle than plasma B cells. Using the Opto Memory B Discovery Rabbit workflow, Berkeley Lights estimates the Beacon platform can: Screen approximately 15,000 to 60,000 single cells per workflow, depending on chip selection and number of chips used per workflow; Identify hundreds to thousands of antigen-specific hits per workflow; and Recover high-quality antibody sequences for the majority of discovered hits.