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    BNTX   US09075V1026


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Press Release : FDA Advisory Committee Votes -2-

09/18/2021 | 03:40am EDT

Individuals should tell the vaccination provider about all of their medical conditions, including if they:

   -- have any allergies 
   -- have had myocarditis (inflammation of the heart muscle) or pericarditis 
      (inflammation of the lining outside the heart) 
   -- have a fever 
   -- have a bleeding disorder or are on a blood thinner 
   -- are immunocompromised or are on a medicine that affects the immune system 
   -- are pregnant, plan to become pregnant, or are breastfeeding 
   -- have received another COVID-19 vaccine 
   -- have ever fainted in association with an injection 

The vaccine may not protect everyone.

Side effects reported with the vaccine include:

   -- There is a remote chance that the vaccine could cause a severe allergic 
          -- A severe allergic reaction would usually occur within a few 
             minutes to one hour after getting a dose of the vaccine. For this 
             reason, vaccination providers may ask individuals to stay at the 
             place where they received the vaccine for monitoring after 
          -- Signs of a severe allergic reaction can include difficulty 
             breathing, swelling of the face and throat, a fast heartbeat, a 
             bad rash all over the body, dizziness, and weakness 
          -- If an individual experiences a severe allergic reaction, they 
             should call 9-1-1 or go to the nearest hospital 
   -- Myocarditis (inflammation of the heart muscle) and pericarditis 
      (inflammation of the lining outside the heart) have occurred in some 
      people who have received the vaccine. In most of these people, symptoms 
      began within a few days following receipt of the second dose of the 
      vaccine. The chance of having this occur is very low. Individuals should 
      seek medical attention right away if they have any of the following 
      symptoms after receiving the vaccine: 
          -- chest pain 
          -- shortness of breath 
          -- feelings of having a fast-beating, fluttering, or pounding heart 
   -- Side effects that have been reported with the vaccine include: 
          -- severe allergic reactions; non-severe allergic reactions such as 
             rash, itching, hives, or swelling of the face; myocarditis 
             (inflammation of the heart muscle); pericarditis (inflammation of 
             the lining outside the heart); injection site pain; tiredness; 
             headache; muscle pain; chills; joint pain; fever; injection site 
             swelling; injection site redness; nausea; feeling unwell; swollen 
             lymph nodes (lymphadenopathy); diarrhea; vomiting; arm pain 
   -- These may not be all the possible side effects of the vaccine. Serious 
      and unexpected side effects may occur. The vaccine is still being studied 
      in clinical trials. Call the vaccination provider or healthcare provider 
      about bothersome side effects or side effects that do not go away 

There is no information on the use of the vaccine with other vaccines.

Patients should always ask their healthcare providers for medical advice about adverse events. Individuals are encouraged to report negative side effects of vaccines to the US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC). Visit https://www.globenewswire.com/Tracker?data=cqMoKZXGH82cJZP8ILzrrixE9H0PTNpl_1Xw4COIb0hneZCe9fld0g_4okfYf9FnPlKRu7I3TtSvplt7b08efIZugsM_sWG1H9Si-YMbWDVlYI5IL4zEcvMhEDpiRoxjUcyMYUDcHdJSyxH9uWHhuliAnE0lR9GtkPFM3Ltdmoma5yTSnFtZcPn_GtAFE8EGbXbqqpVsJ929QBF72PI-od4J8fokyUqZC1wu8w7sklTq1agoSuW0jYS-12T_5sO-_YeB266HBFd9srizV3DeOmJGk_1-uSIfR8LBeIenTqjhnugjE3aVUDvVRBwuHh20 http://www.vaers.hhs.gov or call 1-800-822-7967. In addition, side effects can be reported to Pfizer Inc. at https://www.globenewswire.com/Tracker?data=I_ZXFvkayYcxAO9D6yueBdXKEZ4M5_-IbN3yLxDwCyApKck_R48I91kwpzQeF7-aPCRkQhTuk_Zyo0VlGKjZ0eD_E9jwfkqrt4VhYjhqjZ1tkWuspEcuJfrDILH48H_AaxouqQxW2hvGkRCB3VryQKMa8MUfttm5txxkkRKnt8QMx1LOjPX9RXjIeP5PE-RLUTPcrWvEYpCcKK3q6PK5pFOU9JRy_R0DaETz_0zNee4yvjfNV7GZSLj54rTN82dHWSDVVLEcS2B1QQTly04ojQpHFgHHxuHdxb2zRLZnebIcNAk2i4fE5q6LkQkSdkRo3qtEKEdTcI1ThNQXS5j5ig== www.pfizersafetyreporting.com or by calling 1-800-438-1985.

Please https://www.globenewswire.com/Tracker?data=ZlJrZ6h7-K8kRq_TUZQiR_iS3K8aU4XNVTUiNVTwOhL-ik1hQyFsNRUcJG67VAR-KgV-mhP8CvzNhwSIEA0QW8Nej8Oo5mAs2GHeN-_4BfdpS-h2csMBSNGFU2hWEFO26rn6_emTZUV0-HkVHp3ilyZQJlHUHG6_Dcxp_oyYmrfPbGHMkBTkB1UYSc4eGjEa1PYY50SFcjQeZxBNIdn4oh1GkAQ0YZQrEgS-YEpj421M05nHuLqrW13xEDAqXmuJDrtzl4BYN2iBFL5JgBngMVWrT7LjN-DqwEYKropIbLfjX9B9hTTtqN6OwHfav86TCSB3VyAX-T3ux63kO8yUOw== click here for full Prescribing Information (16+ years of age). Please https://www.globenewswire.com/Tracker?data=ZlJrZ6h7-K8kRq_TUZQiR3-qIAoiHuvDPycWX4ohVTX49R1uMFnO5_OGKGr7nh7YaawMFl-vOQSsDb3COQgfeL0aZgIEf8FMroROEpGXCgxdg1lNXCRoimNuoQZpU4EoEwdLyzIQSlnlYthVfrJ43aN_-8mt9w5cM8Len2mq6dSw4eN5GaL-sudreSo4JXgJYcsg-dJGigVZJSuZFDF34Nny8mY7rCup2hm1qxbnnyIWffCP-Xhza9OFRxRDTOE_IekMwW006vweddyh1W185Q3SCVQFdR5xx1QebTESVvg8YYz4635Hp0Of2FUgxaGksZ9fvhaonoWcMFuo-agRNw== click here for Fact Sheet for Vaccination Providers (12+ years of age).

About Pfizer: Breakthroughs That Change Patients' Lives

At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world's premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For more than 170 years, we have worked to make a difference for all who rely on us. We routinely post information that may be important to investors on our website at https://www.globenewswire.com/Tracker?data=I_ZXFvkayYcxAO9D6yueBW9HY3cmptuRyyOktWDFlbFicw16FTKTQ-CAr-CCkqHjVdJhqoQ6yKaBctwOU5tUx8L01cPvcl6q0PtN3iw61EmqSuWSpV6QgJPGFGajFvczzBaHbwpt76-9mXYcMBCECgQPFcrIXPKL4DdumJSrOV547flfgSXvoiIv7NgCE5g2luA8gvmQfOVTg-ilKtN2orFqRfmkidoFsPtULi0dkuZ9oW_j1koQPw0vjUwkdPA_i2kcD_v6-zQ_NXXNm5FBSAUgPcDtz3SeFqBMXCTGcLk= www.Pfizer.com. In addition, to learn more, please visit us on https://www.globenewswire.com/Tracker?data=I_ZXFvkayYcxAO9D6yueBZo1YzbxWpPPExN8kKi9MmHqNOfr9B0NVOf1zCVd9BOP0kRVVu91tPM7pyMZ5hS14ivfiNppy_Xq1NwIb6HQ4JwFo_JSTQGPStSdNJsKT0Xpxi0EyYfy3Xi9fUbRwx7Dp8MqljBzD8HzGD6-ts4MLG3CID8lxjfW_bGYnPkS0lBoOpB_EwLQpDt3nROdQt6XaZIeeJofV3Wq54GcLGD91oZrSdQXzEKcwCFaR6Y56lCyiZRbcEftqOLHbIMfqPNCvfZB0XJg-m8lFbdCFcu5igI= www.Pfizer.com and follow us on Twitter at https://www.globenewswire.com/Tracker?data=U4k7Xoa5gUH_SddaZhFYLLqh0mEuKEWYDZNcTamLQWtopmTNfpK0s-vVqPVNtevkGp5CSiiJFcA_2HI3uwjelZLCNEytOKbx1_IR7HDK_B2F9S3OiOkVso7LFdkBEDRS2NASQ3UNgm1bI5shq298NvQ3hrcc9Pk8orzMWn7g97xrYPG39-RDitgCzATZRC6LMgMPsVV81yjOaFUdjDS9BPR025z3crHFHWY-XCPNa0OnrXJsnbQM7ZTavhUYWGO9d4BowO8L26grQD_1u4kYng== @Pfizer and https://www.globenewswire.com/Tracker?data=U4k7Xoa5gUH_SddaZhFYLPe6fViBJs5lk2fHVXVg-UUbDrgMzM__2Wsrs7GZYSCziQGt02Hma_FOE-PjhPueaAwQRgbtqVl_qmglWcrMKc5zkOEon_egYxJWnKJyIxDNjDW1E8QtkVouavEed9I597Jp3vH8sVrN2ePydeW126oPypQHQ-GkNpL4x5Nhp4hjpXrj9FSlnS-YDT6odQ83oh01ekUHIpStCj1uU7bCmnq4jXPuPMMfGXNwJeNG__XS7Jl6RSdcWryDwQ5VXPOvhYPnNEwlopUZ-Hu0T6OTP9U= @Pfizer News, https://www.globenewswire.com/Tracker?data=yjB8pDe3eZ6QqRFMxqohhpJjgTRQRQDARUlVRTrBY6sI_CoEVAVhMy6Iy1vWVlJLuvboMvaoqsBvlfxDkoQYZUpkSEOBRA1NLS5M3LEmEGEH3hRqdzLeXZAMSOx5l9-uwZcUqMQp6IjZCJ52Y30xpoFZz0h-l2QKunG7ayNy6c9Jo3fe9um73H6ggF018Lv3iZAVJmTwp-tq20SQ4n_-_KiDHIMF1jUV0eGUJjWvseKoZ7O8wbBc2AVaUKsJpAuvbSWA3ax-svX5UOMqCVMojmCt9VGCU1hVZto-hYJh2sI= LinkedIn, https://www.globenewswire.com/Tracker?data=Zt6JCFMAgE2O99P0HZsnpsWbfn3uH5l8B_vUP7NkJfdcgvbDsVirndAO-s3tu9natCMtODbyhI5Lsxvee3gMgC7M_KrxycKQNDKuTUqwqgG0AHIc7eGTBvaVOhg9SfKJy1XejD8EMC_Yw7DPq2vSGqkdWmMRi8wjob7BJeP7PChbwcupP1nGSnrMPehVWe5lp8NHLqPJxhouO1VixbiheqPSwtQnbkL7PiEox34z03HnTXPGXlyrVVWed6BY0Opmc0oNoeiTv3qVOqQ6MLD0aF92y2UPL0eMpPev8iL_aSU= YouTube and like us on Facebook at https://www.globenewswire.com/Tracker?data=vSuEsC59M97PG99MgkAADWrnUyDp1YgxHNv_f1v6ylPR6xaai7egb_Lr-DKEl5977-82voU9tA3HcoymsC8XNx5PVLl5GaPguAXEAq_-QZv61jifXxM6AGOAVBjn7a9oQVgWnIyRp7Ad1i-WKk1KrvCjb_bOcIcljg7C2ozuC7BP7g7wxgEbko1qo1zqJNMQXtVGsdLE9689GUnTN6F9AQ5_-ua3mGkqr9G-ZthcAsE-ul2uItFzhlEziWfagjW4BwFoYFdldOBkPcCC1ugvsrwqTMU6G8jWk1M_djZtIofn7cL3QrD4W5tDpkaqX4Tg Facebook.com/Pfizer.

Pfizer Disclosure Notice

The information contained in this release is as of September 17, 2021. Pfizer assumes no obligation to update forward-looking statements contained in this release as the result of new information or future events or developments.

This release contains forward-looking information about Pfizer's efforts to combat COVID-19, the collaboration between BioNTech and Pfizer to develop a COVID-19 vaccine, the BNT162 mRNA vaccine program and COMIRNATY (COVID-19 Vaccine, mRNA) (BNT162b2) (including a potential booster (third) dose and a supplemental Biologics License Application (sBLA) for a potential booster (third) dose of BNT162b2 in individuals 16 years of age and older in the U.S., qualitative assessments of available data, potential benefits, expectations for clinical trials, the anticipated timing of regulatory submissions, regulatory approvals or authorizations and anticipated manufacturing, distribution and supply) involving substantial risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. Risks and uncertainties include, among other things, the uncertainties inherent in research and development, including the ability to meet anticipated clinical endpoints, commencement and/or completion dates for clinical

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