BlackRock Science and Technology Trust II : Section 19 Notice - BSTZ September2021

BlackRock Science and Technology Trust II

Cusip: 09260K101

Ticker: BSTZ

Record Date		September 15, 2021
Pay Date		September 30, 2021
Distribution Amount per share	$	0.171000

The following table sets forth the estimated amounts of the current distribution and the cumulative distributions paid this fiscal year to date from the following sources: net income, net realized short-term capital gains, net realized long-term capital gains and return of capital. All amounts are expressed per common share.

						% Breakdown of the
			% Breakdown		Total Cumulative	Total Cumulative
			of the Current		Distributions for the	Distributions for the
	Current Distribution	Distribution		Fiscal Year to Date	Fiscal Year to Date
Net Income	$	-	0%	$	-	0%
Net Realized Short-Term Capital Gains	$	-	0%	$	-	0%
Net Realized Long-Term Capital Gains	$	0.171000	100%	$	1.427000	100%
Return of Capital	$	-	0%	$	-	0%
Total (per common share)	$	0.171000	100%	$	1.427000	100%
Average annual total return (in relation to NAV) for the 5-year period ending on August 31, 2021	143.08%
Annualized current distribution rate expressed as a percentage of NAV as of August 31, 2021	4.71%
Cumulative total return (in relation to NAV) for the fiscal year through August 31, 2021			16.30%
Cumulative fiscal year distributions as a percentage of NAV as of August 31, 2021			2.88%

You should not draw any conclusions about the Trust's investment performance from the amount of this distribution or from the terms of the Trust's Managed Distribution Plan.

The amounts and sources of distributions reported in this Notice are only estimates and are not being provided for tax reporting purposes. The actual amounts and sources of the amounts for tax reporting purposes will depend upon the Fund's investment experience during

its fiscal year and may be subject to changes based on tax regulations. The Fund will send you a Form 1099-DIV for the calendar year that will tell you how to report these distributions for federal income tax purposes.

Contact Number: 800-882-0052