By Ben Glickman


Shares of Bluebird bio fell after the company's sickle-cell disease treatment received a black-box warning and was announced at a higher price point than a competitor's treatment.

The stock was down 41% to $2.84 on Friday. Shares are down 60% this year.

The company's Lyfgenia was approved by the Food and Drug Administration for the treatment of sickle-cell disease. The FDA also approved Casgevy, a sickle-cell treatment developed by Vertex Pharmaceuticals and CRISPR Therapeutics using Crispr gene-modification technology.

The FDA said that Lyfgenia would include a black-box warning related to certain cases of blood cancer in patients treated with the drug.

Bluebird said the treatment would come with a $3.1 million price tag, compared with the $2.2 million price for Casgevy.

Evercore analysts said in a research note that the announcements gave Casgevy an advantage because of its lack of black-box label and lower price.


Write to Ben Glickman at ben.glickman@wsj.com


(END) Dow Jones Newswires

12-08-23 1556ET