Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.



On April 11, 2022, Leslie Norwalk resigned, effective immediately, as a member
of the board of the directors (the "Board") of Centene Corporation (the
"Company"). Consistent with Ms. Norwalk's resignation letter, which is filed
herewith as Exhibit 17.1, the Company believes that Ms. Norwalk resigned because
of her disagreement with Board governance process and Board and committee
leadership.

At the time of her resignation, Ms. Norwalk served on the Board's Compliance
Committee, Environmental and Social Responsibility Committee and Government and
Regulatory Affairs Committee.

As part of its ongoing commitment to strengthening the Company's corporate
governance practices, since November 2021 the Company has implemented
significant governance enhancements, including appointment of five new Board
members, refreshment of Chairs of the Nominating and Governance, Audit, and
Compensation Committees, separation of the roles of CEO and Chairman, the
appointment of a new lead independent director, and the implementation of a
mandatory Board retirement age. In addition, the entire Board is united in its
support for the Company's new CEO, Sarah London, and her highly experienced,
effective leadership team, all of whom are focused on executing the Company's
value creation strategy.

The Company provided Ms. Norwalk with a copy of the disclosures contained in
this Current Report no later than the date on which this Current Report is being
filed with the Securities and Exchange Commission. The Company also provided Ms.
Norwalk with the opportunity to furnish the Company with a letter stating
whether she agrees or disagrees with the statements made in this Current Report
and the respects in which she disagrees.


Item 9.01 Financial Statements and Exhibits.



(d) Exhibits.

  Exhibit Number                                          Description
                           Letter, dated April 11, 2022, Leslie Norwalk to the Board of Directors of
       17.1              Centene Corporation
       99.1                Press release, dated April 15, 2022
       104               Cover Page Interactive Data File (embedded within the Inline XBRL document).




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