Research Assesses CBD and CBN's Potential to Support Improved Sleep
There is limited published preclinical or clinical data on phytocannabinoids other than CBD and THC, especially their effect at levels available in commercially sold hemp-derived CBD supplements. There is some anecdotal evidence on the ability of CBN to help with sleep but little substantiated clinical or preclinical evidence to validate these pervasive claims. Long term, it is anticipated that this study will inform future clinical initiatives to better understand how specific ratios of cannabinoids and different delivery formats are effective at supporting improved sleep quality and instilling healthier sleep architecture in humans.
"Charlotte's Web is committed to advancing science on the benefits and safety of CBD and other hemp phytocannabinoids through rigorous scientific investigations such as this sleep and anxiety study," said
Monika Fleshner, PhD, Professor of Integrative Physiology, and a member of the
"There is a great need for properly controlled experimental studies that are designed to test the potential neural and physiological impacts of hemp derived phytocannabinoids. With support from CU REACH and Charlotte's Web, our research will explore both the efficacy and mechanisms of how these substances can affect complex brain-mediated behavior, such as disturbed sleep."
About CU REACH:
The ultimate objective of CU REACH research is to provide empirical data that will reduce harm and improve lives, in particular the lives of those who suffer from disease states that may be alleviated by Cannabis. Center faculty are diverse, examining the effects of Cannabis at the genetic, molecular, neural, behavioral, and dynamic social systems levels of analysis. Their community currently conducts research in four mutually supporting areas: Cannabis plant genomics and chemical analyses, biomedical pre-clinical and clinical research, risk reduction, and information science.
For more information about CU REACH: https://www.colorado.edu/center/reach/
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