Item 1.01 Entry into a Material Definitive Agreement.

On August 9, 2021, Citrine Global, Corp. (the "Company"), through its 60% owned subsidiary Cannovation Center Israel Ltd. (hereinafter: "Cannovation"), entered into an agreement with iBOT Israel-Botanicals Ltd., a company formed under the laws of the State of Israel ( "iBOT"), pursuant to which iBOT agreed to manufacture a line of nutritional supplements for Cannovation, including packaging and storage (the "Manufacturing Agreement").

iBOT is a botanical nutritional supplements' company developing and manufacturing botanical formulas and nutritional supplements for custom & contract manufacturing for leading botanical companies. iBOT's manufacturing facility is approved by the Israeli Ministry of Health and is GMP-certified, ISO9001-certified and HACCP certified by IQC.

The principal shareholders and control persons of iBOT are the Company's Chief Executive Officer and a Company director.

Cannovation developed the "Green Botanicals" nutritional supplements product line, which includes dozens of unique botanical formulas, and is planning to run clinical trials on several products. Cannovation targets to market the Green Botanicals product line in pharmacies and distribution channels in the medical cannabis field in Israel, initially, and subsequently in Europe, after the requisite approvals are obtained.

Under the Manufacturing Agreement, the parties will agree on the compensation terms for each manufacturing order that Cannovation submits to iBOT It is intended that the price payable to iBOT will be based on the cost of manufacture plus a specified premium to be fixed at the time of each order.

Item 2.01 Completion of Acquisition or Disposition of Assets

Between August 3 - 9, 2021, the Company sold to an unrelated third party in an off market transaction 619,589 ordinary shares of Intelicanna Ltd., an Israeli medical cannabis company listed on the Tel Aviv Stock Exchange ("Intelicanna"), for aggregate gross proceeds to the Company of $ of 1,260,611 NIS (approximately $391,500 based on the current exchange rate). Following the sale, the Company no longer holds any Intelicanna shares. As previously reported, the Company obtained the Intelicanna shares in a share exchange agreement entered into with Intelicanna in September 2020.

The Company's decision to sell the Intelicanna shares was taken, in part, to avoid being subject to the terms of the Investment Company Act of 1940.

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