PHARMAC is seeking feedback on a proposal to fund two new enteral liquid peptide formulas (Nutrini Peptisorb and Nutrini Peptisorb Energy), for use in paediatric patients with impaired gastrointestinal (GI) function, from 1 September 2020 through a provisional agreement with Nutricia Limited (Nutricia).

Listing would be in Section D and Part II of Section H of the Pharmaceutical Schedule and would be subject to Special Authority criteria and Hospital restrictions.

Consultation closes at 5pm Tuesday 4 August 2020 and feedback can be emailed to consult@pharmac.govt.nz.

What would the effect be

From 1 September 2020, Nutrini Peptisorb and Nutrini Peptisorb Energy would be fully funded for paediatric patients who meet the Special Authority criteria (or Hospital restrictions). This would mean that paediatric patients who are tube fed and require a semi-elemental formula would have access to a liquid product.

Currently there are a number of funded semi-elemental and partially hydrolysed formulas available; however, these are powdered formulas which require constitution and do not fully meet the micronutrient needs for all patients. Nutrini Peptisorb and Nutrini Peptisorb Energy are nutritionally complete ready-to-hang formulas suitable for paediatric patients (between the ages of 1 - 14 years) who are unable to tolerate polymeric feeds and alternative semi-elemental or partially hydrolysed formulas (or for whom these feeds are not suitable).

We estimate that approximately 12 paediatric patients per year could benefit from the listing of Nutrini Peptisorb and Nutrini Peptisorb Energy.

Who we think will be interested

Paediatric patients and their whnau

Community and hospital dietitians

Paediatricians, paediatric gastroenterologists, paediatric surgeons, general practitioners, pharmacists and other clinicians and health professionals involved in the management of paediatric patients with impaired gastrointestinal function

Pharmaceutical suppliers and wholesalers

About Nutrini Peptisorb and Nutrini Peptisorb Energy

Impaired GI function can occur as a result of intestinal failure from a variety of causes such as: extensive small bowel mucosal disease, short bowel syndrome, inflammatory bowel disease, pancreatic enzyme deficiency (e.g. secondary to cystic fibrosis), chemotherapy induced enteritis and chronic liver disease. For these patients, impaired digestion and reduced absorption of proteins and lipids can result in inadequate nutritional intake and failure to thrive (poor growth), increasing the risk of malnourishment and impeding overall growth and development.

Nutrini Peptisorb and Nutrini Peptisorb Energy are nutritionally complete liquid peptide (semi-elemental) enteral feeds, designed for paediatric patients with impaired GI function such as maldigestion or malabsorption, who do not tolerate a polymeric feed or for whom a polymeric feed may not be suitable. Both Nutrini Peptisorb and Nutrini Peptisorb Energy can be administered via naso-enteric tube, gastrostomy or jejunostomy.

Nutrini Peptisorb 500 ml is equivalent to a total energy of 500 calories, or 2092kJ, and is indicated for children aged between 1 - 6 years (8-20 kg in weight). Nutrini Peptisorb Energy 500 ml is equivalent to a total energy of 750 calories, or 3138kJ, and is indicated for children up to 45 kg in weight (approximately 12 - 14 years). The volume of Nutrini Peptisorb and Nutrini Peptisorb Energy administered varies based on a patient's individual energy and protein requirements.

Why we're proposing this

A funding application for Nutrini Peptisorb and Nutrini Peptisorb Energy was reviewed by the Special Foods Subcommittee of the Pharmacology and Therapeutics Advisory Committee (PTAC) in December 2017 [PDF, 564 KB]and was recommended for funding with a high priority for paediatric patients with impaired gastrointestinal function who do not tolerate polymeric feeds, or for whom polymeric feeds are not suitable.

This recommendation was noted by PTAC in May 2018 [PDF, 267 KB].

PHARMAC has reached a provisional agreement with the supplier, Nutricia, to fund Nutrini Peptisorb and Nutrini Peptisorb Energy.

Contact:

Tel: 021 863 342

Email: media@pharmac.govt.nz

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