Defence Therapeutics Inc. announced the successful completion of its protein-based COVID vaccine (AccuVAC-PT001) toxicology studies in non-rodent rabbit model. The AccuVAC-PT001 vaccine is an injectable vaccine capable of inducing a powerful and sustainable antibody response in both rodent and non-rodent models. The vaccine proprietary recipe consists of chemically modifying the COVID Spike protein with the AccumTM moiety. Once delivered in animals, the protein accumulates very efficiently in target antigen presenting cells leading to extremely high antibody titers. Extensive analyses conducted on vaccinated rabbits showed no effects induced by the vaccine on animal behaviour, food intake, body weight, skin at injected sites and liver enzymatic function amongst other investigated organs. Defence is currently working on two different protein-based vaccine candidates.