Dräge is collaborating with the Johns Hopkins University Applied Physics Laboratory (APL) and other healthcare industry organizations on the development of a medical device interoperability reference architecture (MDIRA) aimed at improving patient safety through standardization of healthcare delivery. The project is sponsored by the U.S. Army Medical Research and Development Command. Dräger is contributing expertise in standardized medical device interoperability based on the service-oriented device connectivity IEEE 11073 SDC. This web services-based architecture facilitates interoperability among point-of-care medical devices and data exchange between point-of-care devices and HL7 compatible clinical and hospital information systems. It enables a hospital’s medical technologies to share data and information bi-directionally, securely and dynamically. In healthcare, most diagnostic and therapeutic medical devices operate in silos; while they can capture critical patient data, they are unable to communicate it with one another or to the patient’s electronic health record (EHR) in a standardized way. But with SDC, there are significant clinical, operational and cost benefits that could be derived from facilitating data sharing among these devices and capture in the EHR. These benefits include standardized care delivery, more complete and accurate documentation, optimized outcomes and improved patient safety. This project aims to facilitate autonomous medical systems through advanced device interoperability. This would not only allow a caregiver to monitor the status of multiple patients from a remote location and control their therapy settings, but also enable the medical system itself to adjust therapy settings and physiological measurements automatically for an extended period of time. Achieving these goals requires close cooperation among healthcare providers, medical device manufacturers, information technology (IT) solutions providers, regulatory experts and other industry stakeholders. The Johns Hopkins University APL team, in collaboration with Dräger, the Massachusetts General Hospital Medical Device Interoperability and Cybersecurity Program (MD PnP) and others, is conducting research to develop the MDIRA framework for military healthcare interoperability that can subsequently be applied to the civilian healthcare system.