Item 7.01. Regulation FD Disclosure

On February 16, 2021, Dyadic International, Inc. ("Dyadic" or the "Company")'s CEO, Mark Emalfarb, presented and provided an update for investors at the BIO CEO & Investor Digital Conference (the "Presentation"). The Presentation included a discussion of the Company's plan to initiate a potential phase I clinical study related to the Company's proprietary recombinant SARS-CoV-2 Receptor Binding Domain (RBD) antigen, which is produced from the Company's proprietary and patented C1-cells. He also discussed the Company's intention to develop potential Multivalent, Trivalent and/or Tetravalent Recombinant Variant Antigen SARS-CoV-2 Vaccine Product Candidate(s). A copy of the Presentation is accessible on the Company's website at www.dyadic.com under the "Investors" tab. A copy of the Presentation is also attached hereto as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.

The information furnished pursuant to Items 7.01 and 9.01, including the information set forth in Exhibit 99.1, shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such a filing.

Forward-Looking Statements

This Current Report on Form 8-K may contain "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Statements that are not historical in nature, and which may be identified by the use of words such as "expects," "assumes," "projects," "anticipates," "estimates," "we believe," "could be" and other words of similar meaning, are forward-looking statements. These risks and uncertainties include those risk factors discussed in Part I, "Item 1A. Risk Factors" of our Annual Report on Form 10-K for the year ended December 31, 2019 (the "2019 Annual Report"), as they may be updated in any future reports filed with the Securities and Exchange Commission. All forward-looking statements speak only as of the date of this 8-K and are expressly qualified in their entirety by reference to the factors discussed in the 2019 Annual Report. These statements are based on management's expectations and assumptions and are subject to risks and uncertainties that may cause actual results to differ materially from those expressed.

Factors that could cause actual results to differ materially from those contemplated by the forward-looking statements include:




  ? general economic, political and market conditions;


  ? our ability to generate the required productivity, stability, purity,
    performance, cost, safety and other data necessary to carry out and implement
    our biopharmaceutical research and business plans and strategic initiatives;


  ? our ability to retain and attract employees, consultants, directors and
    advisors;


  ? our ability to implement and successfully carry out Dyadic's and third
    parties' research and development efforts;


  ? our ability to obtain new license and research agreements;


  ? our ability to maintain our existing access to, and/or expand access to third
    party contract research organizations in order to carry out our research
    projects for ourselves and third parties;


  ? competitive pressures and reliance on our key customers and collaborators;


  ? the pharmaceutical and biotech industry, governmental regulatory and other
    agencies' willingness to adopt, utilize and approve the use of the C1 gene
    expression platform;


  ? the risk of theft, misappropriation or expiration of owned or licensed
    proprietary and intellectual property, genetic and biological materials owned
    by us and/or Danisco US, Inc. and VTT Technical Research Centre of Finland
    Ltd;


  ? speculative nature and illiquidity of equity securities received as
    consideration from sub-licenses; and


  ? the impact of the novel coronavirus identified as "COVID-19" on our business
    and operating results.

There may be other factors that may cause our actual results to differ materially from the forward-looking statements. Our actual results, performance or achievements could differ materially from those expressed in, or implied by, the forward-looking statements. We can give no assurances that any of the events anticipated by the forward-looking statements will occur or, if any of them do, what impact they will have on our results of operations and financial condition. You should carefully read the factors described in the "Risk Factors" section of the 2020 Annual Report for a description of certain risks that could, among other things, cause our actual results to differ from these forward-looking statements.




Item 9.01 Financial Statements and Exhibits
(d) Exhibits
The following exhibit is being furnished herein:
      Exhibit
      Number          Description

       99.1             Dyadic International Presentation
        104           Cover page Interactive Data File (embedded within the Inline
                      XBRL document)

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