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05/04Earnings Flash (ETX.L) E-THERAPEUTICS Posts FY22 Revenue GBP477,000
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e therapeutics : Interim Results, July 2021 and RNAi Platform Development Presentation

10/26/2021 | 02:26am EDT

Integrating computational power and biology to discover life-transforming medicines

Interim results for six months ended 31 July 2021

Successful RNAi Platform


October 2021


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Forward looking statement

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Company Overview

Integrating computational power and biology to discover life-transforming medicines

Ability to model human biology and interrogate complexity for better and faster drug discovery

  • Experimentally validated computational platform centered around network biology
  • Increased translatability and improved probability of success

• Third party validation

Top5 Pharma

Competitive proprietary RNAi platform developed. Convergence with computational platform to rapidly identify and prosecute novel targets to unlock further value

Experienced leadership and growing multi-disciplinaryteam. Currently 34 FTE

Scope for future partnerships, across computational and RNAi platforms

Well-funded following recent £22.5m capital raise


Highlights (incl. post period)

Significantly strengthened cash position to facilitate a number of initiatives, expanding the Company's platform capabilities and acceleration of the development of in-house RNAi pipeline

RNAi platform development

  • Successful proprietary GalNAc-siRNAplatform developed and characterised. Equivalent performance to leading platforms demonstrated
  • 11 patent applications filed to protect innovative GalNAc-siRNA construct designs

Computational platform - zooming into hepatocytes

  • Hepatocyte Knowledge Graph created and ambitious experimental omics data strategy underway
  • Expanded target identification focus and creation of tailored computational applications in hepatocytes and RNAi
  • Increased automation and cloud computing

Collaborations - further validation of our computational platform

  • Galapagos collaboration: Hit compounds successfully identified and 3 milestone payments received during the period. Collaboration active and hits being further investigated. Scope for further milestones through pre-clinical, clinical and commercial


  • Successful £22.5m gross fund raise from new and existing shareholders
  • Commenced trading on OTCQX Best Market in the U.S. - important step to broaden shareholder base
  • Board and leadership changes and significant increase in scientific staff


Financial Summary: Six months ended 31 July 2021

Six months ended

Six months ended

31 July 2021

31 July 2020




Operating loss



Cash and cash equivalents






Financial Highlights

  • Strengthened financial position following successful fund raise of £22.5m gross
  • Continued to carefully manage the underlying cash burn
  1. focusing on generating income and achieving external commercial validation with our partners and;
  1. investing in a new RNAi platform

Financial Outlook

  • Underlying cash burn in H2 expected to be higher than H1
  1. further progress R&D activities

o build administrative infrastructure to support scaling of business

* £13.0m as of 31 January 2021 5

This is an excerpt of the original content. To continue reading it, access the original document here.


e-Therapeutics plc published this content on 26 October 2021 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 26 October 2021 06:25:06 UTC.

ę Publicnow 2021
05/04Earnings Flash (ETX.L) E-THERAPEUTICS Posts FY22 Revenue GBP477,000
05/04Earnings Flash (ETX.L) E-THERAPEUTICS Posts FY22 Loss GBX-1.65
05/04E-therapeutics plc Announces Change of Registered Office
05/04E-therapeutics plc Reports Earnings Results for the Full Year Ended January 31, 2022
04/12E-therapeutics Achieves Key Milestones Under Collaboration with Galapagos
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2021E-Therapeutics CFO to Step Down; Interim Finance Chief Named
2021E-Therapeutics plc Announces Executive Changes
2021Director Dealing – 26th October 2021
2021E THERAPEUTICS : Interim Results, July 2021 and RNAi Platform Development Presentation
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P/E ratio
Capitalization 117 M 146 M 146 M
EV / Sales -1
EV / Sales 0
Nbr of Employees 35
Free-Float 36,0%
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