DGAP-News: Eckert & Ziegler Strahlen- und Medizintechnik AG / Key word(s): Incoming Orders 
Eckert & Ziegler Signs Long-Term Supply Agreement with Sirtex Medical on Yttrium-90 for Treating Liver Cancer 
2021-04-28 / 12:51 
The issuer is solely responsible for the content of this announcement. 
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Berlin, 28 April 2021. Eckert & Ziegler AG (ISIN DE0005659700, TecDAX) and Sirtex Medical (Sirtex) have executed a 
long-term supply agreement for the use of EZAG's Yttrium-90 in Sirtex SIR-Spheres^(R) Y-90 resin microspheres for liver 
cancer. The arrangement has an initial term of five years and guarantees Eckert & Ziegler a substantial share of 
Sirtex's rising global demand. It supplements the existing broad-based supply agreement that Sirtex and Eckert & 
Ziegler have been operating since 2009. The Eckert & Ziegler sales forecast for the 2021 financial year remains 
unaffected. 
"This agreement cements our long-term relationship and makes it easier for both parties to plan accordingly. The order 
once again underlines our strong market position and competence as a leading production partner for the pharmaceutical 
industry", explains Dr. Lutz Helmke, member of the Executive Board of Eckert & Ziegler AG and responsible for the 
Medical segment. "With our geographic expansion strategy, we offer our customers a reliable and worldwide supply of 
high-quality radioisotopes." 
"With its global manufacturing network, Eckert & Ziegler is an ideal partner for us to supply yttrium-90 worldwide. Our 
therapy is used in more than 50 countries to treat liver cancer, and with our recently announced prospective, 
multi-center study for the treatment of hepatocellular carcinoma, we have the potential to expand our FDA-approved 
indication for the use of SIR-Spheres^(R) in the U.S.," explains Kevin R. Smith, CEO of Sirtex Medical. 
From its production facilities in Braunschweig, Germany, and Boston (MA), USA, Eckert & Ziegler supplies the Sirtex 
sites in Frankfurt, Boston and Singapore with yttrium-90. 
Radioembolisation or selective internal radiotherapy (SIRT) uses tiny radioactive beads inserted directly into the 
liver tumours. The clinical data of this form of therapy, which has been used since 2002, is becoming increasingly 
convincing. In February 2021, the renowned British National Institute for Health and Care Excellence (NICE) issued a 
positive recommendation for the treatment of advanced liver carcinomas with SIR-Spheres^(R) Y-90 resin microspheres. 
Every year, around 840,000 people worldwide develop liver cancer (source: Globocan, 2018). 
To meet the increasing demand for radiopharmaceutical substances, Eckert & Ziegler is currently expanding its 
production sites. A new GMP facility will be added to the Boston (MA), USA site at the end of 2021. In Berlin, a new 
GMP facility with a total area of around 270 m² will be ready for operation in the first quarter of 2022. In Jintan 
(China), Eckert & Ziegler is investing up to EUR 50 million in the construction of a production facility for 
radiopharmaceuticals. 
This expansion strategy positions Eckert & Ziegler as a global partner to the radiopharmaceutical industry, offering 
complete early development services, including process development and scale-up, CMC development, manufacturing and 
packaging, product release and stability programmes. This will enable the company to be a radiopharmaceutical contract 
manufacturer of phase I, II and III clinical scale products and for commercial use. 
About Eckert & Ziegler. 
Eckert & Ziegler Strahlen- und Medizintechnik AG with more than 800 employees, is one of the world's largest providers 
of isotope-related components for nuclear medicine and radiation therapy. The company offers services for 
radiopharmaceuticals at its worldwide locations, from early development to commercialization. Eckert & Ziegler shares 
(ISIN DE0005659700) are listed in the TecDAX index of Deutsche Börse. 
Contributing to saving lives. 
Your contact: 
Eckert & Ziegler AG, Karolin Riehle, Investor Relations 
Robert-Rössle-Str. 10, 13125 Berlin, Germany 
Tel.: +49 (0) 30 / 94 10 84-138, karolin.riehle@ezag.de, www.ezag.com 
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2021-04-28 Dissemination of a Corporate News, transmitted by DGAP - a service of EQS Group AG. 
The issuer is solely responsible for the content of this announcement. 
The DGAP Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases. 
Archive at www.dgap.de 
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Language:     English 
Company:      Eckert & Ziegler Strahlen- und Medizintechnik AG 
              Robert-Rössle-Str.10 
              13125 Berlin 
              Germany 
Phone:        +49 30 941084-138 
Fax:          +49 30 941084-112 
E-mail:       karolin.riehle@ezag.de 
Internet:     www.ezag.de 
ISIN:         DE0005659700 
WKN:          565970 
Indices:      SDAX 
Listed:       Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Berlin, Dusseldorf, 
              Hamburg, Munich, Stuttgart, Tradegate Exchange 
EQS News ID:  1189939 
 
End of News   DGAP News Service 
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1189939 2021-04-28


 
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(END) Dow Jones Newswires

April 28, 2021 06:51 ET (10:51 GMT)