Item 2.01 Completion of Acquisition or Disposition of Assets.
As described above, on August 24, 2021, LWAC held the Special Meeting, at which
the LWAC stockholders considered and adopted, among other matters, a proposal to
approve the Merger Agreement and the Transactions. On August 25, 2021, the
parties consummated the Business Combination. In connection with the Closing,
the Company changed its name from Locust Walk Acquisition Corp. to eFFECTOR
Therapeutics, Inc. In addition, in connection with the Closing, each share of
LWAC Class A common stock was reclassified as common stock of the Company.
Holders of 16,978,642 shares of LWAC Class A common stock sold in its initial
public offering (the "Initial Shares") properly exercised their right to have
such shares redeemed for a full pro rata portion of the trust account holding
the proceeds from LWAC's initial public offering, calculated as of two business
days prior to the consummation of the business combination, which was
approximately $10.00 per share, or $169,786,420 in the aggregate.
As a result of the Business Combination, each share of Old eFFECTOR preferred
stock and common stock was converted into the right to receive approximately
0.09657 shares of eFFECTOR's common stock, par value $0.0001 per share ("Common
Stock") for an aggregate of 30,021,762 shares of Common Stock issued in the
Business Combination. Former holders of shares of Old eFFECTOR common stock
(including shares received as a result of the conversion of Old eFFECTOR
preferred stock and the exercise of Old eFFECTOR warrants) will also be entitled
to receive their pro rata share of up to 5,000,000 shares of Common stock if, on
or prior to May 26, 2023, the closing share price of shares of Common Stock
equals or exceeds $20.00 over at least 20 trading days within a
30-day
trading period (the "Triggering Event") and, in respect of each former holder of
Old eFFECTOR stock options, such holder continues to provide services to
eFFECTOR or one of its subsidiaries at the time of such Triggering Event. The
Earn-Out
Shares will also be earned and issuable in the event of a change in control of
eFFECTOR on or prior to May 26, 2023 that results in the holders of Common Stock
receiving a
per-share
price equal to or in excess of $20.00.
Additionally, the shares of LWAC Class B common stock held by Sponsor
automatically converted into shares of Common Stock. In connection with the
Closing, the Sponsor agreed to forfeit 1,000,000 shares of LWAC Class B common
stock and as a result, the Sponsor received 3,511,250 shares of Common Stock
upon conversion of the Class B common stock (of which 300,000 are subject to
vesting if, on or prior to August 25, 2024, the price of shares of Common Stock
equals or exceeds $15.00 per share). Following the Closing, Sponsor holds an
aggregate of 4,056,250 shares of Common Stock including the 3,511,250 shares
received upon conversion of the Class B common stock and 545,000 shares of LWAC
Class A common stock held prior to the Closing.
Pursuant to subscription agreements entered into in connection with the Merger
Agreement (collectively, the "Subscription Agreements"), certain investors
agreed to subscribe for an aggregate of 6,070,003 newly-issued shares of Common
Stock at a purchase price of $10.00 per share for an aggregate purchase price of
$60.7 million (the "PIPE Investment"). At the Closing, eFFECTOR consummated the
PIPE Investment.
After giving effect to the Transactions, the redemption of Initial Shares as
described above, and the consummation of the PIPE Investment, there are
currently 40,669,373 shares of Common Stock issued and outstanding. In
connection with the Closing, options to purchase shares of Old eFFECTOR common
stock were converted into options to purchase an aggregate of 3,920,657 shares
of Common Stock, with a weighted-average exercise price of $1.56 per share.
The Common Stock and warrants commenced trading on the Nasdaq Capital Market
("Nasdaq") under the symbols "EFTR" and "EFTRW," respectively, on August 26,
2021, subject to ongoing review of eFFECTOR's satisfaction of all listing
criteria following the Business Combination.
As noted above, an aggregate of $169.8 million was paid from the Company's trust
account to holders that properly exercised their right to have Initial Shares
redeemed, and the remaining balance immediately prior to the Closing of
approximately $5.2 million remained in the trust account. The remaining amount
in the trust account was used to pay expenses in connection with the Business
Combination.
--------------------------------------------------------------------------------
                              FORM 10 INFORMATION
Item 2.01(f) of Form
8-K
provides that if the predecessor registrant was a "shell company" (as such term
is defined in Rule
12b-2
under the Securities Exchange Act of 1934, as amended (the "Exchange Act")), as
LWAC was immediately before the Business Combination, then the registrant must
disclose the information that would be required if the registrant were filing a
general form for registration of securities on Form 10. As a result of the
consummation of the Business Combination, and as discussed below in Item 5.06 of
this Report, the Company has ceased to be a shell company. Accordingly, the
Company is providing the information below that would be included in a Form 10
if it were to file a Form 10. Please note that the information provided below
relates to the combined company after the consummation of the Business
Combination, unless otherwise specifically indicated or the context otherwise
requires.
Cautionary Note Regarding Forward-Looking Statements
This Report includes statements that express eFFECTOR's opinions, expectations,
beliefs, plans, objectives, assumptions or projections regarding future events
or future results and therefore are, or may be deemed to be, "forward-looking
statements." These forward-looking statements can generally be identified by the
use of forward-looking terminology, including the terms "believes," "estimates,"
"anticipates," "expects," "seeks," "projects," "intends," "plans," "may" or
"should" or, in each case, their negative or other variations or comparable
terminology. These forward-looking statements include all matters that are not
historical facts. They appear in a number of places throughout this Report
(including in information that is incorporated by reference into this Report)
and include statements regarding our intentions, beliefs or current expectations
concerning, among other things, the Transactions and the benefits of the
Transactions, including results of operations, financial condition, liquidity,
prospects, growth, strategies and the markets in which eFFECTOR operates. Such
forward-looking statements are based on available current market material and
management's expectations, beliefs and forecasts concerning future events
impacting eFFECTOR. Factors that may impact such forward-looking statements
include:

     •    the results of eFFECTOR's clinical trials of its product candidates
          tomivosertib and zotatifin, which are in Phase 2 clinical development;



     •    difficulties or delays in the commencement or completion, or termination
          or suspension, of eFFECTOR's current or planned clinical trials;



     •    difficulties in enrolling patients in eFFECTOR's clinical trials,
          including as a result of the parti
          al
           clinical hold on its ongoing Phase 2b KICKSTART trial;



  •   the impact of the
      COVID-19
      pandemic on the financial condition and results of operations of eFFECTOR;



  •   eFFECTOR's future capital needs following the Business Combination;



     •    the ability of eFFECTOR to maintain an effective system of internal
          control over financial reporting;



  •   the ability of eFFECTOR to maintain and protect its intellectual property;



     •    eFFECTOR's reliance on single-source suppliers and third-party
          manufacturers;



  •   litigation, complaints, product liability claims and/or adverse publicity;



     •    privacy and data protection laws, privacy or data breaches, or the loss
          of data;



  •   the ability of eFFECTOR to manage its growth effectively;



  •   the ability of eFFECTOR to achieve and maintain profitability in the future;



  •   the success of strategic relationships with third parties;



     •    the ability of eFFECTOR to maintain the listing of the Common Stock and
          warrants of eFFECTOR on Nasdaq;



     •    the ability of eFFECTOR to remediate existing and potential future
          material weaknesses in eFFECTOR's internal control over financial
          reporting and to maintain effective internal control over financial
          reporting, which, if unsuccessful, may result in material misstatements
          of eFFECTOR's consolidated financial statements or failure to meet
          periodic reporting obligations or impair access to the capital markets;



     •    other factors detailed under the section titled "Risk Factors" beginning
          on page 36 of the Proxy Statement/Prospectus and incorporated herein by
          reference.


The foregoing list of factors is not exhaustive. You should carefully consider
the foregoing factors and the other risks and uncertainties described in the
"Risk Factors" section of the other documents filed by eFFECTOR from time to
time with the SEC. The forward-looking statements contained in this Report and
in any document incorporated by reference are based on current expectations and
beliefs concerning future developments and their
--------------------------------------------------------------------------------
potential effects on eFFECTOR. There can be no assurance that future
developments affecting eFFECTOR will be those that eFFECTOR has anticipated.
eFFECTOR undertakes no obligation to update or revise any forward-looking
statements, whether as a result of new information, future events or otherwise,
except as may be required under applicable securities laws.
Business
eFFECTOR's business is described in the Proxy Statement/Prospectus in the
section titled "
Business of eFFECTOR
" beginning on page 158, which is incorporated herein by reference.
Risk Factors
The risks associated with eFFECTOR's business are described in the Proxy
Statement/Prospectus in the section titled "
Risk Factors
" beginning on page 36 and are incorporated herein by reference. A summary of
the risks associated with eFFECTOR's business is also included on pages
24-26
of the Proxy Statement/Prospectus under the heading "
Summary of Risk Factors
" and are incorporated herein by reference.
Financial Information
The (i) audited financial statements of Old eFFECTOR as of and for the years
ended December 31, 2020 and 2019 and (ii) unaudited condensed financial
statements of Old eFFECTOR as of March 31, 2021 and for the three months ended
March 31, 2021 and 2020 are included in the Proxy Statement/Prospectus beginning
on pages
F-42
and
F-69,
respectively, of the Proxy Statement/Prospectus, which are incorporated herein
by reference.
The unaudited condensed financial information of Old eFFECTOR as of and for the
three and six months ended June 30, 2021 is set forth in Exhibit 99.1 hereto and
is incorporated herein by reference.
The unaudited pro forma condensed combined financial information of LWAC and Old
eFFECTOR as of and for the six months ended June 30, 2021 and for the year ended
December 31, 2020 is set forth in Exhibit 99.3 hereto and is incorporated herein
by reference.
Management
'
s Discussion and Analysis of Financial Condition and Results of Operations
Management's discussion and analysis of the financial condition and results of
operation of Old eFFECTOR as of and for the years ended December 31, 2020 and
2019 and for the three months ended March 31, 2021 is included in the Proxy
Statement/Prospectus in the section titled "
Management
'
s Discussion and Analysis of Financial Condition and Results of Operations of
eFFECTOR
" beginning on page 202 of the Proxy Statement/Prospectus, which is incorporated
herein by reference.
Management's discussion and analysis of the financial condition and results of
operations of Old eFFECTOR as of and for the three and six months ended June 30,
2021 is set forth is set forth in Exhibit 99.2 hereto and is incorporated herein
by reference.
Quantitative and Qualitative Disclosures about Market Risk
Management's discussion and analysis of the quantitative and qualitative
disclosures about market risk is included in the Proxy Statement/Prospectus in
the section titled "
Management's Discussion and Analysis of Financial Condition and Results of
Operations of eFFECTOR-Quantitative and Qualitative Disclosures about Market
Risk
" beginning on page 218, which is incorporated herein by reference.
Properties
Our headquarters are located at 11120 Roselle Street, Suite A, San Diego, CA,
where we lease approximately 3,501 square feet of office space. The lease for
our headquarters expires on December 31, 2021. We believe that our existing
facilities are adequate for our near-term needs. We believe that suitable
additional or alternative space would be available if required in the future on
commercially reasonable terms.
--------------------------------------------------------------------------------
Security Ownership of Certain Beneficial Owners and Management
The following table sets forth the beneficial ownership of Common Stock
following the consummation of the Business Combination and the PIPE Investment
as of August 25, 2021 by:

     •    each person who is known to be the beneficial owner of more than 5% of
          shares of Common Stock;



  •   each of eFFECTOR's current named executive officers and directors; and



  •   all current executive officers and directors of eFFECTOR as a group.


The beneficial ownership of common stock is based on 40,669,373 shares of common
stock outstanding following the consummation of the Business Combination and
PIPE Investment.
Beneficial ownership is determined according to the rules of the SEC, which
generally provide that a person has beneficial ownership of a security if he,
she or it possesses sole or shared voting or investment power over that
security, including options and warrants that are currently exercisable or
exercisable within 60 days.
Unless otherwise indicated, eFFECTOR believes that all persons named in the
table below have sole voting and investment power with respect to the voting
securities beneficially owned by them.

Name and Address of Beneficial Owner                      Number of            % of
(1)                                                         Shares           Ownership
5% Holders
Entities affiliated with SR One Capital
(2)                                                         6,822,114              16.8 %
Entities affiliated with U.S. Venture Partners
(3)                                                         4,822,114              11.9 %
Abingworth Bioventures VI, L.P.
(4)                                                         4,822,114              11.9 %
The Column Group II, LP
(5)                                                         4,309,329              10.6 %
Locust Walk Sponsor, LLC
(6)                                                         4,237,917              10.4 %
Entities affiliated with Altitude Life Sciences
Ventures
(7)                                                         2,826,350               6.9 %
New Emerging Medical Opportunities Fund III, L.P.
(8)                                                         2,822,744               7.1 %
Pfizer Venture Investments
(9)                                                         2,243,850               5.5 %
Directors and Executive Officers
Stephen T. Worland, Ph.D.
(10)                                                        2,060,149               4.9 %
Michael Byrnes                                                 70,416                 *
Premal Patel, M.D., Ph.D.
(11)                                                          132,784                 *
Alana B. McNulty
(12)                                                          535,842               1.3 %
Elizabeth P. Bhatt                                              9,047                 *
Chris Ehrlich
(13)                                                          143,202                 *
Brian M. Gallagher
(4)                                                         4,822,114              11.9 %
Laurence Lasky, Ph.D.                                              -                 -
Jonathan D. Root, M.D.
(3)                                                         4,822,114              11.9 %
John W. Smither
(14)                                                           48,284                 *
All directors and executive officers as a group (10
individuals)
(15)                                                       12,643,952              29.6 %



* Less than one percent

(1) Unless otherwise noted, the business address of each of those listed in the

table above is 11120 Roselle Street, Suite A, San Diego, California 92121.

(2) Represents 4,822,114 shares held by SR One Capital Fund I Aggregator, LP (SR


    One Capital Fund) and 2,000,000 shares held by SR One
    Co-Invest
    I, LLC (SR One
    Co-Invest).
    SR One Capital Partners I, LP (SR One Capital Partners) is the general
    partner of SR One Capital Fund. SR One
    Co-Invest
    I Manager, LLC (SR One
    Co-Invest
    Manager) is the managing member of SR One
    Co-Invest.
    SR One Capital Management, LLC (SR One Capital Management) is the general
    partner of SR One Capital Partners and the managing member of

--------------------------------------------------------------------------------


    SR One
    Co-Invest
    Manager. Simeon George, M.D. is the managing member of SR One Capital
    Management. By virtue of such relationships, Dr. George, SR One Capital
    Partners, SR One Capital Management and SR One
    Co-Invest
    Manager may be deemed to have voting and investment power with respect to the
    shares held by SR One Capital Fund and/or SR One
    Co-Invest,
    as applicable, and as a result may be deemed to have beneficial ownership of
    such shares. Each of Dr. George, SR One Capital Partners, SR One Capital and
    SR One
    Co-Invest
    Manager disclaims beneficial ownership of the shares held by SR One Capital
    Fund and SR One
    Co-Invest,
    except to the extent of its or his pecuniary interest therein if any. The
    address for SR One Capital Fund I Aggregator, LP and SR One
    Co-Invest
    I, LLC is 985 Old Eagle School Road, Suite 511, Wayne, PA 19087.

(3) Represents 4,672,628 shares held by U.S. Venture Partners X, L.P. (USVP X),


    and 149,486 shares held by USVP X Affiliates, L.P. (AFF X, and together with
    USVP X, the USVP X Funds). Presidio Management Group X, LLC (PMG X) is the
    general partner of the USVP Funds has sole voting and dispositive power with
    respect to the shares held by the USVP X Funds. Jonathan D. Root, a member of
    our Board, is a managing member of PMG X with additional rights with respect
    to the issuer's securities, and may be deemed to have sole voting and
    dispositive power with respect to the shares. Casey M. Tansey is the sole
    managing partner of PMG X and may be deemed to have sole dispositive power
    and shared voting power over the reported shares. Each of the foregoing
    persons disclaims beneficial ownership of shares held by the USVP X Funds,
    except to the extent of any proportionate pecuniary interest therein. The
    address for U.S. Venture Partners is 1460 El Camino Real, Suite 100, Menlo
    Park, CA 94025.

(4) Abingworth Bioventures VI GP LP, a Scottish limited partnership, serves as


    the general partner of ABV VI. Abingworth General Partner VI LLP, an English
    limited liability partnership, serves as the general partner of Abingworth
    Bioventures VI GP LP. ABV VI (acting by its general partner Abingworth
    Bioventures VI GP LP, acting by its general partner Abingworth General
    Partner VI LLP) has delegated to Abingworth LLP, an English limited liability
    partnership, all investment and dispositive power over the securities held by
    ABV VI. An investment committee of Abingworth LLP, comprised of Timothy
    Haines, Kurt von Emster, Genghis Lloyd-Harris, Bali Muralidhar, Andrew
    Sinclair and Brian Gallagher, a member of our Board, approves investment and
    voting decisions by a specified majority vote, and no individual member has
    the sole control or voting power over the securities held by ABV VI. Each of
    Abingworth Bioventures VI GP LP, Abingworth General Partner VI LLP, Timothy
    Haines, Kurt von Emster, Genghis Lloyd-Harris, Bali Muralidhar, Andrew
    Sinclair and Brian Gallagher disclaims beneficial ownership of the securities
    held by the ABV VI except to the extent of their proportionate pecuniary
    interest therein. The address for ABV VI and each of the other entities and
    individuals listed in this footnote is c/o Abingworth LLP, Princes House, 38
    Jermyn Street, London, England SW1Y 6DN.

(5) Peter Svennilson and David Goeddel, Ph.D. are the managing partners of The

Column Group II GP, LP, which is the general partner of The Column Group II,
    LP and may be deemed to have shared voting, investment and dispositive power
    with respect to these shares. Each individual managing partner disclaims
    beneficial ownership of these shares, except to the extent of their pecuniary
    interest in such shares. The principal address of The Column Group II, L.P.
    is 1 Letterman Drive, Bldg D, Suite
    DM-900,
    San Francisco, California 94158.

(6) Represents 4,056,250 shares of Common Stock and warrants to purchase up to


    181,667 shares of Common Stock. Locust Walk Partners, LLC is the manager of
    Locust Walk Sponsor, LLC (LWAC Sponsor). Geoff Meyerson is the CEO &
    Co-founder of Locust Walk Partners and may be deemed to have voting,
    investment and dispositive power with respect to these shares. Mr. Meyerson
    disclaims beneficial ownership of these securities, except to the extent of
    his pecuniary interest therein. The business address of Locust Walk Partners,
    LLC is 200 Clarendon Street, 51st Floor, Boston, MA 02116.

(7) Represents 1,413,175 shares by Altitude Life Sciences Ventures Fund II, L.P.


    and 1,413,175 shares held by Altitude Life Sciences Ventures Side Fund II,
    L.P. David Maki is the managing member of Altitude Life Science Ventures II,
    LLC, which is the general partner of each of Altitude Life Science Ventures
    Fund II, L.P. and Altitude Life Science Ventures Side Fund II, L.P., and
    holds voting, investment and dispositive power with respect to these shares.
    The address for the Altitude Life Science Ventures is 1014 Market Street,
    Suite 200, Kirkland, WA 98074.

--------------------------------------------------------------------------------

(8) Sectoral Asset Management Inc., in its capacity as investment adviser to New


    Emerging Medical Opportunities Fund III, L.P. (NEMO), has the sole right to
    dispose of or vote the NEMO shares and is the owner of the general partner
    (Sectoral GP III L.P.) of Nemo. Sectoral Asset Management, Inc. and Stefan
    Larson disclaim beneficial ownership of the NEMO shares. The mailing address
    for NEMO is c/o Sectoral Asset Management Inc. at 1010 Sherbrooke St. West,
    #1610, Montreal, QC Canada H3A 2R7.

(9) Pfizer Venture Investments LLC (Pfizer Ventures) is a wholly-owned subsidiary


    of Pfizer Inc., a publicly traded company (Pfizer). By virtue of the
    relationship between Pfizer and Pfizer Ventures, Pfizer may be deemed to have
    beneficial ownership of shares held by Pfizer Ventures. Pfizer's address is
    235 East 42nd Street, New York, New York 10017.

(10) Represents 755,480 shares held by a family trust of Dr. Worland of which he

is a trustee and 1,304,669 shares underlying options to purchase shares of

Common Stock.

(11) Represents 123,932 shares underlying options to purchase shares of Common

Stock.

(12) Represents 485,062 shares underlying options to purchase shares of Common

Stock.

(13) Represents 142,168 shares of Common Stock held directly by LWAC Sponsor and


     allocated to Mr. Ehrlich by Locust Walk Partners LLC (LWP), a member of LWAC
     Sponsor, and 1,034 shares of Common Stock held directly by LWAC Sponsor and
     allocated to Mr. Ehrlich's spouse by LWP.

(14) Represents 24,142 shares underlying options to purchase shares of Common

Stock.

(15) Represents 10,624,867 shares of Common stock and 2,019,085 options to

purchase shares of Common Stock.




Executive Officers and Directors
eFFECTOR's directors and executive officers after the consummation of the
Business Combination are described in the Proxy Statement/Prospectus in the
section titled "
Management After the Merger
" beginning on page 260 and that information is incorporated herein by
reference.
Upon consummation of the Business Combination, each executive officer of LWAC
ceased serving in such capacities, and each of Brian G. Atwood, Daniel Geffken,
Barbara A. Kosacz and Caroline M. Loewy ceased serving on LWAC's board of
directors.
Upon consummation of the Business Combination, Dr. Worland was appointed as
eFFECTOR's President and Chief Executive Officer, Michael Byrnes was appointed
as eFFECTOR's Chief Financial Officer and Secretary, Alana B. McNulty was
appointed as eFFECTOR's Chief Business Officer and Premal Patel, M.D., Ph.D. was
appointed as eFFECTOR's Chief Medical Officer.
Upon consummation of the Business Combination, Elizabeth P. Bhatt, Chris
Ehrlich, Brian M. Gallagher, Jr., Ph.D., Laurence Lasky, Ph.D., Jonathan D.
Root, M.D., John W. Smither and Stephen T. Worland, Ph.D. were appointed as
directors of eFFECTOR by the holders of Class B common stock of LWAC, to serve
until the end of their respective terms and until their successors are elected
and qualified, with Dr. Gallagher appointed to serve as Chairman of the Board.
Following the Business Combination, eFFECTOR's Board is divided into three
classes with staggered, three-year terms. At each annual meeting of
stockholders, the directors whose terms then expire will be eligible for
reelection until the third annual meeting following reelection. Dr. Root and
Mr. Worland will serve as the initial Class I directors for a term expiring at
the first annual meeting of the stockholders; Mr. Ehrlich, Dr. Gallagher and
Mr. Smither will serve as the initial Class II directors for a term expiring at
the second annual meeting of the stockholders; and Ms. Bhatt and Dr. Lasky will
serve as the initial Class III directors for a term expiring at the third annual
meeting of the stockholders.
--------------------------------------------------------------------------------
Executive and Director Compensation
The compensation of eFFECTOR's executive officers and directors is described in
the Proxy Statement/Prospectus in the section titled "
eFFECTOR
'
s
Executive and Director Compensation
" beginning on page 265 and that information is incorporated herein by
reference.
Certain Relationships and Related Transactions
Certain relationships and related party transactions of eFFECTOR are described
in the Proxy Statement/Prospectus in the section titled "
Certain Relationships and Related Transactions
" beginning on page 277 and are incorporated herein by reference.
Legal Proceedings
eFFECTOR is not currently a party to any material legal proceedings. However,
from time to time, eFFECTOR may become involved in legal proceedings or be
subject to claims arising in the ordinary course of our business. Regardless of
outcome, such proceedings or claims can have an adverse impact on us because of
defense and settlement costs, diversion of resources and other factors, and
there can be no assurances that favorable outcomes will be obtained.
Market Price of and Dividends on the Registrant
'
s Common Equity and Related Stockholder Matters
Market Information
Shares of eFFECTOR's Common Stock and eFFECTOR's warrants commenced trading on
Nasdaq under the symbols "EFTR" and "EFTRW," respectively, on August 26, 2021,
subject to ongoing review of eFFECTOR's satisfaction of all listing criteria
following the Business Combination, in lieu of the Class A common stock,
warrants and units of LWAC. LWAC's units ceased trading separately on Nasdaq on
August 25, 2021. Information respecting LWAC's Class A common stock, warrants
and units and related stockholder matters are described in the Proxy
Statement/Prospectus in the section titled "
Trading Market and Dividends
" on page 35 and such information is incorporated herein by reference.
Holders
As of the Closing and following the completion of the Transactions, including
the redemption of Initial Shares as described above and the consummation of the
PIPE Investment, the Company had 40,669,373 shares of Common Stock outstanding
held of record by 88 holders, no shares of preferred stock outstanding, and
6,015,000 warrants outstanding held of record by two holders. Such amounts do
. . .

© Edgar Online, source Glimpses