Continuous Dosing

FDA Approval as

Monotherapy

Statistically Significant

PALOMA-3

MONALEESA-3 & 7

Overall Survival Benefit in

Metastatic Breast Cancer

Additional AI trial ongoing in 1L post-menopausal setting

Additional AI trial ongoing in 1L post-menopausal setting

Additional AI trial ongoing in 1L post-menopausal setting

Positive Trial in

PALLAS

? NATALEE

Adjuvant Setting

(PENELOPE-B adjuvant trial ongoing, late 2020 readout)

(2022 Interim, 2025 Primary readout)

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The most rapid timeline in the development of an oncology

medicine with multiple indications

Less than 3 Years

First Human Dose to Approval

Systemic Treatment

Treatment

Cabozantinib/

Cabozantinib/

Systemic Treatment

Treatment

Naïve

Experienced

Vandetanib Naïve

Vandetanib

Naïve

Experienced

Experienced

RET Fusion-Positive NSCLC

RET-Mutant MTC

RET Fusion-Positive Thyroid Cancers

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Eli Lilly and Company published this content on 21 September 2020 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 21 September 2020 16:19:02 UTC