Income Statement
LLY
Eli Lilly and Company
Reconciliation of GAAP Reported to Selected Non-GAAP Adjusted Information*
Investor Relations
Kevin Hern (317) 277-1838
Sara Smith (317) 690-1424
Kento Ueha (317) 651-3258
Lauren Zierke (317) 277-6524
Three Months Ended Three Months Ended Twelve Months Ended Twelve Months Ended
($ in millions, except per share data) December 31, 2021 December 31, 2020 December 31, 2021 December 31, 2020
GAAP Reported % chng Adjustments Non-GAAP Adjusted % chng GAAP Reported Adjustments Non-GAAP Adjusted GAAP Reported % chng Adjustments Non-GAAP Adjusted % chng GAAP Reported Adjustments Non-GAAP Adjusted
Revenue $7,999.9 8% - $7,999.9 8% $7,440.0 - $7,440.0 $28,318.4 15% - $28,318.4 15% $24,539.8 - $24,539.8
Cost of sales 2,050.2 19% (137.4) 1,912.8 20% 1,719.8 (127.3) 1,592.5 7,312.8 33% (908.8) 6,404.0 26% 5,483.3 (415.2) 5,068.1
Gross margin 5,949.7 4% 137.4 6,087.1 4% 5,720.2 127.3 5,847.5 21,005.6 10% 908.8 21,914.4 13% 19,056.5 415.2 19,471.7
% of total revenue 74.4% (2.5) pp 76.1% (2.5) pp 76.9% 78.6% 74.2% (3.5) pp 77.4% (1.9) pp 77.7% 79.3%
Research and development 1,898.3 9% - 1,898.3 9% 1,744.4 - 1,744.4 6,930.7 16% - 6,930.7 16% 5,976.3 - 5,976.3
Marketing, selling, and administrative 1,592.0 2% - 1,592.0 2% 1,553.9 - 1,553.9 6,431.6 5% - 6,431.6 5% 6,121.2 - 6,121.2
Acquired IPR&D and development milestones † 437.7 (5)% - 437.7 (5)% 459.9 - 459.9 970.1 26 % - 970.1 26 % 769.8 - 769.8
Asset impairment, restructuring, and other special charges 104.5 NM (104.5) - - % (30.1) 30.1 - 316.1 NM (316.1) - - % 131.2 (131.2) -
Operating income 1,917.2 (4)% 241.9 2,159.1 3 % 1,992.1 97.2 2,089.3 6,357.1 5 % 1,224.9 7,582.0 15 % 6,058.0 546.4 6,604.4
Interest, net (74.0) - (74.0) (83.4) - (83.4) (314.4) - (314.4) (326.6) - (326.6)
Other income (3.3) 70.6 67.3 560.4 (508.0) 52.4 112.8 227.2 340.0 1,498.5 (1,322.7) 175.8
Other - net, income (expense) (77.3) NM 70.6 (6.7) (78)% 477.0 (508.0) (31.0) (201.6) NM 227.2 25.6 NM 1,171.9 (1,322.7) (150.8)
Income before income taxes 1,839.9 (25)% 312.5 2,152.4 5 % 2,469.1 (410.8) 2,058.3 6,155.5 (15)% 1,452.1 7,607.6 18 % 7,229.9 (776.3) 6,453.6
Income tax expense 113.8 (68)% 68.1
Joe Alterio: Joe Alterio: $.02 needed to get to $181.9, which agrees to cell R47 on "2021 NOR" tab.
181.9 (32)% 352.3 (85.8) 266.5 573.8 (45)% 300.1
Joe Alterio: Joe Alterio: $.02 needed to get to $873.9, which agrees to cell M47 on "2021 NOR" tab.

Joe Alterio: Joe Alterio: $.02 needed to get to $181.9, which agrees to cell R47 on "2021 NOR" tab.
873.9 3 % 1,036.2 (188.6) 847.6
Effective tax rate 6.2% (8.1) pp 8.5% (4.4) pp 14.3% 12.9% 9.3% (5.0) pp 11.5% (1.6) pp 14.3% 13.1%
Net income 1,726.1 (18)% 244.4 1,970.5 10 % 2,116.8 (325.0) 1,791.8 5,581.7 (10)% 1,152.0 6,733.7 20 % 6,193.7 (587.7) 5,606.0
Earnings per share 1.90 (18)% 0.27 2.17 10 % 2.32 (0.36) 1.96 6.12 (10)% 1.27
Joe Alterio: Joe Alterio: $.01 adjustment to tie to $7.39 reported on cell M81 of "2021 NOR" tab
7.39 20 % 6.79 (0.65)
Joe Alterio: Joe Alterio: Adjusted .01 to arrive at total of $6.14 which matches cell U30 of "Significant Items" tab (and $6.14 also is the correct amount mathematically when taking W38/W42*1000)
6.14
Diluted shares outstanding (thousands) 909,555 - % - 909,555 - % 912,591 - 912,591 911,681 - % - 911,681 - % 912,505 - 912,505
* The company uses non-GAAP financial measures that differ from financial statements reported in conformity with U.S. generally accepted accounting principles (GAAP). The company's non-GAAP measures adjust reported results to exclude amortization of intangibles and items that are typically highly variable, difficult to predict, and/or of a size that could have a substantial impact on the company's reported operations for a period. The company believes that these non-GAAP measures provide useful information to investors. Among other things, they may help investors evaluate the company's ongoing operations. They can assist in making meaningful period-over-period comparisons and in identifying operating trends that would otherwise be masked or distorted by the items subject to the adjustments. Management uses these non-GAAP measures internally to evaluate the performance of the business, including to allocate resources and to evaluate results relative to incentive compensation targets. Investors should consider these non-GAAP measures in addition to, not as a substitute for or superior to, measures of financial performance prepared in accordance with GAAP. For additional information on the adjustments, refer to 'Significant Items'.
† Beginning in 2022, non-GAAP financial measures will not include adjustments for upfront charges and development milestones related to IPR&D projects. Non-GAAP financial measures for the three and twelve months ended December 31, 2021 have been adjusted to reflect this updated presentation.
Note: Numbers may not add due to rounding.
Page 1 of 6 pages of financial data
Significant Items
LLY
Eli Lilly and Company
Significant Items Affecting Net Income
Investor Relations
Kevin Hern (317) 277-1838
Sara Smith (317) 690-1424
Kento Ueha (317) 651-3258
Lauren Zierke (317) 277-6524
Significant Items Affecting Net Income
2021 2020
Q1 Q2 Q3 Q4 Total Q1 Q2 Q3 Q4 Total
Earnings per share (reported) $ 1.49 $ 1.53 $ 1.22 $ 1.90 $ 6.12 $ 1.60 $ 1.55 $ 1.33 $ 2.32 $ 6.79
Charge related to repurchase of higher-cost debt - - 0.35 - 0.35 - - - - -
Asset impairment, restructuring and other special charges 0.19 - - 0.09 0.28 0.06 - 0.11 (0.03) 0.14
Amortization of intangible assets 0.11 0.12 0.12 0.19 0.53 0.05 0.09 0.11 0.11 0.36
COVID-19 antibodies inventory charges 0.07 0.37 (0.11) (0.07) 0.25 - - - - -
Net losses (gains) on investments in equity securities (0.25) (0.16) 0.19 0.06 (0.16) (0.14) (0.44) (0.13) (0.44) (1.15)
Earnings per share (non-GAAP) * $ 1.61 $ 1.85 $ 1.77 $ 2.17 $ 7.39 $ 1.56 $ 1.20 $ 1.41 $ 1.96 $ 6.14
Acquired IPR&D and Development Milestones † 0.27 0.04 0.17 0.39 0.86 0.05 0.25 - 0.44 0.75
* The company uses non-GAAP financial measures that differ from financial statements reported in conformity with U.S. generally accepted accounting principles (GAAP). The company's non-GAAP measures adjust reported results to exclude amortization of intangibles and items that are typically highly variable, difficult to predict, and/or of a size that could have a substantial impact on the company's reported operations for a period. The company believes that these non-GAAP measures provide useful information to investors. Among other things, they may help investors evaluate the company's ongoing operations. They can assist in making meaningful period-over-period comparisons and in identifying operating trends that would otherwise be masked or distorted by the items subject to the adjustments. Management uses these non-GAAP measures internally to evaluate the performance of the business, including to allocate resources and to evaluate results relative to incentive compensation targets. Investors should consider these non-GAAP measures in addition to, not as a substitute for or superior to, measures of financial performance prepared in accordance with GAAP. For additional information on the adjustments, refer to 'Significant Items'.
† For informational purposes only -- included in the Earnings per share (reported) and Earnings per share (non-GAAP) amounts above.
Note: Numbers may not add due to rounding.
Page 2 of 6 pages of financial data
2021 Revenue
LLY
Eli Lilly and Company
Product Revenue Report
2021
Investor Relations
Kevin Hern (317) 277-1838
Sara Smith (317) 690-1424
Kento Ueha (317) 651-3258
Lauren Zierke (317) 277-6524
2021 Revenue
($ millions) Q1 Q1 Q1 Q2 Q2 Q2 Q3 Q3 Q3 Q4 Q4 Q4 2021 2021 2021
US Intl Total US Intl Total US Intl Total US Intl Total US Intl Total
Baqsimi 20.6 3.8 24.4 22.3 3.6 25.9 27.6 4.3 31.9 25.9 5.1 31.0 96.4 16.8 113.2
Basaglar 175.2 71.4 246.6 133.4 77.3 210.7 114.7 78.1 192.8 165.0 77.4 242.4 588.3 304.2 892.5
Glucagon 20.4 1.4 21.8 7.9 1.5 9.3 8.5 2.0 10.4 6.9 1.9 8.8 43.7 6.7 50.4
Humalog(1) 332.7 284.4 617.0 329.1 278.6 607.6 347.3 279.4 626.7 311.7 290.0 601.7 1,320.7 1,132.3 2,453.0
Humulin 219.0 102.7 321.7 221.1 94.3 315.3 193.4 93.4 286.7 199.4 99.4 298.8 832.9 389.6 1,222.6
Jardiance(2) 151.2 160.8 312.0 194.4 162.1 356.5 221.2 169.2 390.4 240.5 191.4 431.9 807.3 683.5 1,490.8
Trajenta(3) 21.0 73.6 94.6 16.8 72.4 89.2 23.4 72.7 96.1 20.9 71.7 92.6 82.1 290.4 372.5
Trulicity 1,116.8 335.7 1,452.4 1,147.6 388.0 1,535.6 1,201.4 398.8 1,600.1 1,448.6 435.1 1,883.7 4,914.4 1,557.6 6,471.9
Other Diabetes* 4.3 16.1 20.6 7.2 17.9 25.4 5.5 33.2 39.0 16.4 20.2 36.6 33.5 87.7 121.2
Diabetes 2,061.2 1,049.9 3,111.1 2,079.8 1,095.7 3,175.5 2,143.0 1,131.1 3,274.1 2,435.3 1,192.2 3,627.5 8,719.3 4,468.8 13,188.1
Olumiant 24.7 169.1 193.8 17.8 190.6 208.4 194.0 212.9 406.9 87.7 218.3 306.0 324.1 791.0 1,115.1
Qbrexza 10.5 - 10.5 4.7 - 4.7 - - - - - - 15.2 - 15.2
Taltz 249.6 153.6 403.2 399.8 169.3 569.1 422.2 170.9 593.1 470.8 176.6 647.4 1,542.4 670.4 2,212.8
Other Immunology* - 6.4 6.4 0.1 3.2 3.2 - 4.9 4.9 - 3.2 3.2 0.1 17.6 17.6
Immunology 284.8 329.1 613.9 422.4 363.1 785.4 616.2 388.7 1,004.9 558.5 398.1 956.5 1,881.8 1,479.0 3,360.7
Cymbalta 11.0 165.7 176.6 12.4 163.3 175.6 7.0 125.1 132.0 8.4 88.8 97.2 38.7 542.8 581.5
Emgality 101.5 18.0 119.5 112.1 44.2 156.3 99.9 40.1 140.0 121.0 40.4 161.5 434.5 142.7 577.2
Reyvow 2.5 - 2.5 9.4 - 9.4 5.4 (0.2) 5.3 6.4 0.4 6.9 23.8 0.3 24.0
Strattera 6.1 32.6 38.6 7.6 32.9 40.5 2.6 32.5 35.2 1.2 34.9 36.1 17.5 132.8 150.4
Zyprexa 6.9 88.9 95.8 8.4 86.9 95.4 13.0 88.7 101.7 11.3 126.2 137.5 39.6 390.7 430.3
Other Neuroscience* 13.7 18.5 32.4 16.8 18.2 35.0 16.7 19.3 36.0 13.4 18.2 31.4 60.7 74.4 135.0
Neuroscience 141.7 323.7 465.4 166.7 345.5 512.2 144.6 305.5 450.2 161.7 308.9 470.6 614.8 1,283.7 1,898.4
Alimta 261.1 297.8 559.0 353.5 257.1 610.6 297.2 159.8 457.0 322.0 112.8 434.9 1,233.9 827.5 2,061.4
Cyramza 80.2 160.3 240.5 101.4 167.3 268.7 84.8 168.6 253.4 91.9 178.6 270.4 358.1 674.8 1,033.0
Erbitux 107.9 14.4 122.4 135.8 11.2 147.0 114.0 20.3 134.3 124.1 20.5 144.6 481.8 66.4 548.3
Retevmo 16.3 0.5 16.8 22.5 3.2 25.7 29.2 4.4 33.6 31.4 7.2 38.6 99.4 15.4 114.7
Tyvyt - 109.7 109.7 - 105.0 105.0 - 125.6 125.6 - 77.8 77.8 - 418.1 418.1
Verzenio 172.8 96.2 269.0 209.7 131.6 341.3 199.6 135.9 335.5 252.8 151.3 404.1 834.9 515.0 1,349.9
Other Oncology* 4.2 50.8 54.8 5.4 50.3 55.7 6.1 60.7 66.7 4.9 33.7 38.5 20.7 195.3 215.9
Oncology 642.5 729.7 1,372.2 828.3 725.7 1,554.0 730.9 675.3 1,406.1 827.1 581.9 1,408.9 3,028.8 2,712.5 5,741.3
COVID-19 Antibodies 650.6 159.5 810.1 83.4 65.7 148.9 215.5 1.6 217.1 1,028.5 34.6 1,063.1 1,978.0 261.4 2,239.2
Cialis 8.6 118.1 126.8 (5.2) 286.3 281.0 (6.5) 137.4 130.9 13.6 166.1 179.7 10.6 707.9 718.4
Forteo 97.7 100.8 198.5 122.8 95.6 218.4 109.6 91.3 200.9 111.4 72.6 184.0 441.6 360.3 801.9
Humatrope 32.3 32.6 64.9 (10.2) 32.6 22.4 19.3 31.0 50.2 22.6 28.9 51.4 63.9 125.1 189.0
Other* 21.9 20.8 42.6 16.2 25.8 42.2 17.0 21.4 38.6 17.2 40.7 58.1 72.3 108.8 181.3
Other 811.1 431.8 1,242.9 207.0 506.0 712.9 354.9 282.7 637.7 1,193.3 342.9 1,536.3 2,566.4 1,563.5 4,129.8
TOTAL REVENUE 3,941.3 2,864.3 6,805.6 3,704.2 3,035.9 6,740.1 3,989.6 2,783.3 6,772.8 5,175.9 2,824.0 7,999.9 16,811.0 11,507.4 28,318.4
*Other - Diabetes includes Actos, Competact, Evista, HumaPen, and Lyumjev. Other - Immunology includes Lebrikizumab. Other - Neuro includes Amyvid, Prozac, Symbyax, and Yentreve. Other - Oncology includes Elunate, Gemzar, Halpryza, Portrazza, and Vitrakvi. Other - Other includes Adcirca, Ceclor, Effient, Keflex, Livalo, Zalutia, and other license fee income.
(1) Humalog revenue includes Insulin Lispro
(2) Jardiance revenue includes Glyxambi and Synjardy
(3) Trajenta revenue includes Jentadueto
Note: Numbers may not add due to rounding.
Page 3 of 6 pages of financial data
2021 Revenue Growth
LLY
Eli Lilly and Company
Product Revenue Growth Report
2021
Investor Relations
Kevin Hern (317) 277-1838
Sara Smith (317) 690-1424
Kento Ueha (317) 651-3258
Lauren Zierke (317) 277-6524
2021 Revenue Growth
Q1 Q1 Intl Q1 Q1 Q2 Q2 Intl Q2 Q2 Q3 Q3 Intl Q3 Q3 Q4 Q4 Intl Q4 Q4 2021 2021 Intl 2021 2021
US Intl Perform** Total Perform** US Intl Perform** Total Perform** US Intl Perform** Total Perform** US Intl Perform** Total Perform** US Intl Perform** Total Perform**
Baqsimi 30 % 93 % 85 % 37 % 36 % NM 42 % 34 % 90 % 89 % 0 62 % 12 % 9 % 53 % 53 % 31 % 26 % 26 % 30 % 30 % 51 % 35 % 32 % 49 % 48 %
Basaglar (24)% (3)% (8)% (19)% (20)% (42)% 27 % 19 % (27)% (29)% (36)% 12 % 10 % (22)% (23)% (19)% (1)% - % (14)% (14)% (30)% 8 % 5 % (21)% (21)%
Glucagon (24)% 4 % - % (22)% (22)% (64)% 37 % 21 % (59)% (60)% (63)% 6 % (1)% (58)% (58)% (68)% NM NM (60)% (61)% (53)% 32 % 23 % (48)% (49)%
Humalog(1) (17)% (4)% (9)% (11)% (13)% 17 % 2 % (5)% 9 % 6 % (11)% 5 % 1 % (5)% (6)% (25)% (4)% (4)% (16)% (16)% (11)% (1)% (5)% (7)% (8)%
Humulin 2 % 1 % (3)% 2 % 1 % 3 % (5)% (12)% 1 % (1)% (10)% 2 % (3)% (6)% (8)% (11)% (1)% (2)% (8)% (8)% (4)% (1)% (5)% (3)% (4)%
Jardiance(2) 5 % 31 % 19 % 17 % 11 % 34 % 39 % 31 % 36 % 33 % 35 % 15 % 21 % 26 % 29 % 43 % 31 % 33 % 38 % 39 % 30 % 28 % 26 % 29 % 28 %
Trajenta(3) (27)% 14 % (3)% 1 % (11)% 2 % 20 % 17 % 16 % 14 % 21 % 1 % 7 % 5 % 10 % (33)% 9 % 9 % (4)% (4)% (14)% 10 % 7 % 4 % 2 %
Trulicity 20 % 12 % 5 % 18 % 16 % 20 % 40 % 31 % 25 % 23 % 52 % 26 % 23 % 45 % 44 % 25 % 28 % 29 % 25 % 26 % 28 % 26 % 22 % 28 % 27 %
Other Diabetes* 64 % 6 % 3 % 15 % 12 % NM 27 % 24 % 68 % 65 % NM NM NM NM NM NM 4 % 8 % 81 % 85 % NM 37 % 37 % 73 % 72 %
Diabetes 4 % 7 % - % 5 % 2 % 11 % 21 % 13 % 14 % 12 % 19 % 15 % 14 % 18 % 17 % 8 % 13 % 13 % 10 % 10 % 10 % 14 % 10 % 11 % 10 %
Olumiant NM 32 % 23 % 39 % 31 % 35 % 45 % 37 % 44 % 36 % NM 44 % 42 % NM NM NM 30 % 32 % 59 % 61 % NM 38 % 34 % 75 % 71 %
Qbrexza NM - % - % NM - % (5)% - % - % (5)% (5)% (100)% - % - % (100)% (100)% NM - % - % NM NM (24)% - % - % (24)% (24)%
Taltz (24)% 32 % 23 % (9)% (12)% 38 % 60 % 48 % 44 % 41 % 29 % 33 % 31 % 30 % 30 % 36 % 18 % 20 % 31 % 31 % 20 % 34 % 29 % 24 % 22 %
Other Immunology* - % NM NM NM NM - % 3 % 3 % 3 % 3 % - % 8 % 8 % 8 % 8 % - % (51)% (51)% (51)% (51)% - % 21 % 21 % 21 % 21 %
Immunology (16)% 34 % 25 % 5 % 1 % 37 % 51 % 41 % 43 % 39 % 78 % 39 % 37 % 60 % 59 % 48 % 23 % 25 % 37 % 37 % 37 % 36 % 32 % 37 % 35 %
Cymbalta (5)% (17)% (20)% (16)% (20)% 60 % (5)% (6)% (2)% (3)% (38)% (29)% (28)% (29)% (28)% (27)% (50)% (49)% (49)% (47)% (8)% (25)% (26)% (24)% (25)%
Emgality 51 % NM NM 61 % 60 % 39 % NM NM 79 % 77 % 23 % NM NM 53 % 52 % 25 % NM NM 47 % 47 % 33 % NM NM 59 % 58 %
Reyvow 77 % NM NM 77 % 77 % NM NM NM NM NM 35 % NM NM 31 % 31 % 60 % 23 % 23 % 57 % 57 % 92 % (31)% (31)% 89 % 89 %
Strattera NM (8)% (13)% 1 % (3)% NM 12 % 7 % 80 % 73 % 11 % 7 % 5 % 8 % 6 % NM (1)% - % 3 % 4 % NM 2 % (1)% 17 % 14 %
Zyprexa (39)% 2 % (4)% (3)% (8)% (7)% (1)% (7)% (1)% (7)% (39)% (3)% (5)% (10)% (11)% NM 34 % 36 % 39 % 41 % (14)% 8 % 5 % 6 % 3 %
Other Neuroscience* (14)% (26)% (26)% (21)% (21)% 59 % (19)% (22)% 6 % 4 % (17)% (16)% (18)% (17)% (18)% (17)% (6)% (5)% (11)% (10)% (4)% (17)% (18)% (12)% (12)%
Neuroscience 29 % (8)% (13)% - % (3)% 60 % 8 % 5 % 21 % 19 % 3 % (7)% (8)% (4)% (5)% 22 % (10)% (8)% (1)% - % 26 % (4)% (6)% 4 % 2 %
Alimta (19)% 26 % 17 % - % (4)% 11 % 16 % 10 % 13 % 11 % 2 % (44)% (45)% (21)% (21)% (3)% (65)% (64)% (33)% (33)% (2)% (22)% (26)% (12)% (13)%
Cyramza (10)% 7 % 3 % 1 % (2)% 8 % 3 % 2 % 5 % 4 % (10)% 7 % 8 % - % 1 % (12)% (1)% 4 % (5)% (2)% (6)% 4 % 4 % - % - %
Erbitux (8)% 11 % 10 % (6)% (7)% 17 % (18)% (17)% 14 % 14 % (7)% 45 % 48 % (2)% (1)% - % 31 % 35 % 4 % 4 % - % 18 % 20 % 2 % 2 %
Retevmo NM NM NM NM NM NM NM NM NM NM NM NM NM NM NM 69 % NM NM NM NM NM NM NM NM NM
Tyvyt - % 91 % 79 % 91 % 79 % - % 64 % 50 % 64 % 50 % - % 49 % 38 % 49 % 38 % - % (24)% (27)% (24)% (27)% - % 35 % 26 % 35 % 26 %
Verzenio 34 % 64 % 57 % 43 % 41 % 48 % 97 % 91 % 64 % 62 % 26 % 80 % 80 % 43 % 43 % 34 % 62 % 67 % 43 % 45 % 35 % 75 % 74 % 48 % 48 %
Other Oncology NM 75 % 66 % NM 100 % (27)% (11)% (17)% (13)% (18)% 95 % 85 % 79 % 86 % 80 % NM (1)% (3)% 6 % 5 % NM 28 % 23 % 33 % 28 %
Oncology (2)% 34 % 26 % 14 % 11 % 21 % 24 % 18 % 23 % 20 % 7 % 4 % 2 % 5 % 5 % 8 % (22)% (21)% (7)% (6)% 8 % 7 % 4 % 8 % 7 %
COVID-19 Antibodies NM NM NM NM NM NM NM NM NM NM NM NM NM NM NM 21% 62% 63% 22% 22% NM NM NM NM NM
Cialis (67)% (29)% (30)% (34)% (35)% NM NM NM NM NM NM (7)% (9)% (19)% (21)% NM 34 % 34 % 49 % 48 % (83)% 30 % 28 % 18 % 16 %
Forteo (20)% (33)% (36)% (27)% (29)% 3 % (28)% (31)% (14)% (15)% (24)% (25)% (26)% (25)% (25)% (10)% (45)% (43)% (28)% (27)% (13)% (33)% (34)% (23)% (24)%
Humatrope (39)% (9)% (14)% (27)% (29)% NM 1 % (3)% (51)% (55)% 9 % (6)% (6)% (1)% (1)% (69)% (23)% (20)% (54)% (53)% (60)% (10)% (11)% (36)% (37)%
Other* (17)% (65)% (66)% (50)% (51)% (6)% (24)% (28)% (18)% (20)% 8 % (30)% (30)% (17)% (17)% (41)% (31)% (29)% (34)% (33)% (18)% (41)% (41)% (33)% (34)%
Other NM 5 % 3 % 94 % 93 % 19 % 65 % 61 % 48 % 46 % 84 % (15)% (16)% 21 % 20 % 11 % (8)% (7)% 6 % 7 % 54 % 10 % 8 % 34 % 33 %
TOTAL REVENUE 18 % 13 % 7 % 16 % 13 % 18 % 29 % 23 % 23 % 20 % 26 % 8 % 7 % 18 % 17 % 13 % (1)% 1 % 8 % 8 % 18 % 12 % 9 % 15 % 14 %
*Other - Diabetes includes Actos, Competact, Evista, HumaPen, and Lyumjev. Other - Immunology includes Lebrikizumab. Other - Neuro includes Amyvid, Prozac, Symbyax, and Yentreve. Other - Oncology includes Elunate, Gemzar, Halpryza, Portrazza, and Vitrakvi. Other - Other includes Adcirca, Ceclor, Effient, Keflex, Livalo, Zalutia, and other license fee income.
**Performance excludes the impact of foreign exchange rates
(1) Humalog revenue includes Insulin Lispro
(2) Jardiance revenue includes Glyxambi and Synjardy
(3) Trajenta revenue includes Jentadueto
Note: Numbers may not add due to rounding.
Page 4 of 6 pages of financial data
PRV
LLY
Eli Lilly and Company
Effect of Price, Rate, Volume on Revenue
Investor Relations
Kevin Hern (317) 277-1838
Sara Smith (317) 690-1424
Kento Ueha (317) 651-3258
Lauren Zierke (317) 277-6524
As Reported ($ millions) Q1 2021 Q2 2021 Q3 2021 Q4 2021 2021 YTD
$ Price Rate Volume Total $ Price Rate Volume Total $ Price Rate Volume Total $ Price Rate Volume Total $ Price Rate Volume Total
Region
U.S. $ 3,941.3 (6 %) - % 24 % 18 % $ 3,704.2 (1)% - % 18 % 18 % $ 3,989.6 4 % - % 22 % 26 % $ 5,175.9 (2)% - % 14 % 13 % $ 16,811.0 (1)% - % 19 % 18 %
Europe 1,321.2 (0 %) 10 % 15 % 24 % 1,209.8 (1)% 11 % 28 % 38 % 1,098.6 (2)% 2 % 5 % 5 % 1,147.3 (3)% (1)% 0 % (5)% 4,776.8 (2)% 5 % 11 % 14 %
Japan 571.8 (2 %) 4 % (6 %) (3 %) 665.4 (3)% (2)% 5 % 0 % 595.0 1 % (4)% (6)% (10)% 534.8 (2)% (6)% (11)% (19)% 2,367.0 (2)% (2)% (5)% (8)%
China 362.2 (6 %) 9 % 32 % 35 % 522.5 (19)% 12 % 125 % 118 % 400.3 (23)% 9 % 53 % 38 % 376.5 (30)% 4 % 44 % 17 % 1,661.4 (20)% 8 % 61 % 49 %
ROW 609.1 (2 %) 1 % 2 % (0 %) 638.1 (2)% 6 % 7 % 11 % 689.4 (3)% 2 % 18 % 18 % 765.5 (3)% 1 % 19 % 17 % 2,702.2 (3)% 2 % 12 % 12 %
Total Revenue $ 6,805.6 (4 %) 3 % 17 % 16 % $ 6,740.1 (2)% 3 % 22 % 23 % $ 6,772.8 0 % 1 % 17 % 18 % $ 7,999.9 (3)% 0 % 11 % 8 % $ 28,318.4 (2)% 1 % 16 % 15 %
ROW - OUS excluding Europe, Japan, and China
Note: Numbers may not add due to rounding.
Page 5 of 6 pages of financial data
OID
LLY
Eli Lilly and Company
Other Income/(Deductions)
Investor Relations
Kevin Hern (317) 277-1838
Sara Smith (317) 690-1424
Kento Ueha (317) 651-3258
Lauren Zierke (317) 277-6524
2021 2020
As Reported
$ Millions Q1 Q2 Q3 Q4 Total Q1 Q2 Q3 Q4 Total
- Interest expense $ (87.8) $ (86.9) $ (83.6) $ (81.4) $ (339.8) $ (92.5) $ (88.3) $ (89.6) $ (89.2) $ (359.6)
- Interest income 5.5 5.4 7.0 7.4 25.4 14.3 7.1 5.8 5.8 33.0
Interest - net (82.3) (81.5) (76.6) (74.0) (314.4) (78.2) (81.2) (83.8) (83.4) (326.6)
Other income, net
- FX gain (loss) (10.6) (10.8) (10.9) (5.4) (37.8) (16.7) (10.3) (4.8) (15.4) (47.2)
- Gain (loss) equity investments 301.5 215.7 (246.8) (93.5) 176.9 186.6 576.8 141.7 537.1 1,442.2
- Gain (loss) debt extinguishment - - (405.2) - (405.2) - - - - -
- Miscellaneous income (expense) 39.1 (4.0) 31.0 23.0 89.2 (47.2) (74.3) (8.2) (18.6) (148.3)
- Retirement Benefit 73.4 71.1 72.6 72.6 289.7 44.6 35.9 114.0 57.3 251.8
Other income (expense) 403.4 272.0 (559.3) (3.3) 112.8 167.3 528.1 242.7 560.4 1,498.5
Other - net, income (expense) $ 321.1 $ 190.5 $ (635.9) $ (77.3) $ (201.6) $ 89.1 $ 446.9 $ 158.9 $ 477.0 $ 1,171.9
2021 2020
Non-GAAP*
$ Millions Q1 Q2 Q3 Q4 Total Q1 Q2 Q3 Q4 Total
- Interest expense $ (87.8) $ (86.9) $ (83.6) $ (81.4) $ (339.8) $ (92.5) $ (88.3) $ (89.6) $ (89.2) $ (359.6)
- Interest income 5.5 5.4 7.0 7.4 25.4 14.3 7.1 5.8 5.8 33.0
Interest - net (82.3) (81.5) (76.6) (74.0) (314.4) (78.2) (81.2) (83.8) (83.4) (326.6)
Other income, net
- FX gain (loss) (10.6) (10.8) (10.9) (5.4) (37.8) (16.7) (10.3) (4.8) (15.4) (47.2)
- Gain (loss) equity investments - - - - - - - - - -
- Gain (loss) debt extinguishment - - - - - - - - - -
- Miscellaneous income (expense) 54.1 26.2 7.6 0.1 88.1 (22.3) (1.5) (15.5) 10.5 (28.8)
- Retirement Benefit 73.4 71.1 72.6 72.6 289.7 44.6 35.9 114.0 57.3 251.8
Other income (expense) 116.9 86.5 69.3 67.3 340.0 5.6 24.1 93.7 52.4 175.8
Other - net, income (expense) $ 34.6 $ 5.0 $ (7.3) $ (6.7) $ 25.6 $ (72.6) $ (57.1) $ 9.9 $ (31.0) $ (150.8)
*The company uses non-GAAP financial measures that differ from financial statements reported in conformity with U.S. generally accepted accounting principles (GAAP). The company's non-GAAP measures adjust reported results to exclude amortization of intangibles and items that are typically highly variable, difficult to predict, and/or of a size that could have a substantial impact on the company's reported operations for a period. The company believes that these non-GAAP measures provide useful information to investors. Among other things, they may help investors evaluate the company's ongoing operations. They can assist in making meaningful period-over-period comparisons and in identifying operating trends that would otherwise be masked or distorted by the items subject to the adjustments. Management uses these non-GAAP measures internally to evaluate the performance of the business, including to allocate resources and to evaluate results relative to incentive compensation targets. Investors should consider these non-GAAP measures in addition to, not as a substitute for or superior to, measures of financial performance prepared in accordance with GAAP.
Note: Numbers may not add due to rounding.
Page 6 of 6 pages of financial data
Proof-Qtrly
LLY
Eli Lilly and Company
Reconciliation of GAAP Reported to Selected Non-GAAP Adjusted Information*
Three Months Ended Three Months Ended Three Months Ended Three Months Ended
($ in millions, except per share data) March 31, 2021 March 31, 2020 June 30, 2021 June 30, 2020
GAAP Non-GAAP GAAP Non-GAAP GAAP Non-GAAP GAAP Non-GAAP
Reported Adjustments Adjusted Reported Adjustments Adjusted Reported Adjustments Adjusted Reported Adjustments Adjusted
Revenue $6,805.6 - $6,805.6 $5,859.8 - $5,859.8 $6,740.1 - $6,740.1 $5,499.4 - $5,499.4
Cost of sales 1,878.6 (207.2) 1,671.4 1,215.1 (58.6) 1,156.5 1,953.2 (555.2) 1,398.0 1,222.0 (102.8) 1,119.2
Research and development 1,684.8 - 1,684.8 1,392.1 - 1,392.1 1,672.8 - 1,672.8 1,390.2 - 1,390.2
Marketing, selling, and administrative 1,576.0 - 1,576.0 1,549.6 - 1,549.6 1,685.7 - 1,685.7 1,448.6 - 1,448.6
Operating expenses 3,260.8 - 3,260.8 2,941.7 - 2,941.7 3,358.5 - 3,358.5 2,838.8 - 2,838.8
Acquired in-process research and s/b 0 s/b 0 s/b 0 s/b 0
development 299.3 - 299.3 52.3 - 52.3 25.0 - 25.0 241.8 - 241.8
Asset impairment, restructuring,
and other special charges 211.6 (211.6) - 59.9 (59.9) - - - - - - -
Other - net, income (expense) 321.1 (286.5) 34.6 89.1 (161.7) (72.6) 190.5 (185.5) 5.0 446.9 (504.0) (57.1)
. . . .
Income taxes 121.1 22.1 143.2 223.4 (16.5) 206.9 203.7 76.3 280.0 231.7 (84.5) 147.2
Add: IPRD taxes (from Earnings Release) 62.9 62.9 11.0 11.0 5.3 5.3 14.1 14.1
Sum of above two rows of data 85.0 206.1 (5.5) 217.9 81.6 285.3 (70.4) 161.3
Reported on IR_workbook_Q4_2021 85.0 206.1 (5.5) 217.9 81.6 285.3 (70.4) 161.3
Proof - - - - - - - -
Net income 1,355.3 110.2 1,465.5 1,456.5 (26.7) 1,429.8 1,390.2 293.4 1,683.6 1,412.0 (316.7) 1,095.3
Add: IPRD net income (from Earnings Release) 236.4 236.4 41.3 41.3 19.7 19.7 227.7 227.7
Sum of above two rows of data 346.6 1,701.9 14.6 1,471.1 313.1 1,703.3 (89.0) 1,323.0
Reported on IR_workbook_Q4_2021 346.6 1,701.9 14.6 1,471.1 313.1 1,703.3 (89.0) 1,323.0
Proof - - - - - - - -
Earnings per share 1.49 0.12 1.61 1.60 (0.04) 1.56 1.53 0.32 1.85 1.55 (0.35) 1.20
Add: IPRD EPS (from Earnings Release) 0.26 0.26 0.05 0.05 0.02 0.02 0.25 0.25
Sum of above two rows of data 0.38 1.87 0.01 1.61 0.34 1.87 (0.10) 1.45
Reported on IR_workbook_Q4_2021 0.38 1.87 0.01 1.61 0.34 1.87 (0.10) 1.45
Proof - - - - - - - -
Three Months Ended Three Months Ended Three Months Ended Three Months Ended
September 30, 2021 September 30, 2020 December 31, 2021 December 31, 2020
GAAP Non-GAAP GAAP Non-GAAP GAAP Non-GAAP GAAP Non-GAAP
Reported Adjustments Adjusted Reported Adjustments Adjusted Reported Adjustments Adjusted Reported Adjustments Adjusted
Revenue $6,772.8 - $6,772.8 $5,740.6 - $5,740.6 $7,999.9 - $7,999.9 $7,440.0 - $7,440.0
Cost of sales 1,430.8 (9.0) 1,421.8 1,326.4 (126.5) 1,199.9 2,050.2 (137.4) 1,912.8 1,719.8 (127.3) 1,592.5
Research and development 1,708.9 - 1,708.9 1,465.4 - 1,465.4 1,959.4 - 1,959.4 1,838.0 - 1,838.0
Marketing, selling, and administrative 1,577.9 - 1,577.9 1,569.1 - 1,569.1 1,592.0 - 1,592.0 1,553.9 - 1,553.9
Operating expenses 3,286.8 - 3,286.8 3,034.5 - 3,034.5 3,551.4 - 3,551.4 3,391.9 - 3,391.9
Acquired in-process research and s/b 0 s/b 0 s/b 0 s/b 0
development 174.0 - 174.0 - - - 376.6 - 376.6 366.3 - 366.3
Asset impairment, restructuring,
and other special charges - - - 101.4 (101.4) - 104.5 (104.5) - (30.1) 30.1 -
Other - net, income (expense) (635.9) 628.6 (7.3) 158.9 (149.0) 9.9 (77.3) 70.6 (6.7) 477.0 (508.0) (31.0)
Income taxes 135.2 133.5 268.7 228.8 (1.9) 226.9 113.8 68.1 181.9 352.3 (85.8) 266.5
Add: IPRD taxes (from Earnings Release) 24.5 24.5 - - 79.3 79.3 50.4 50.4
Sum of above two rows of data 158.0 293.2 (1.9) 226.9 147.4 261.2 (35.4) 316.9
Reported on IR_workbook_Q4_2021 158.0 293.2 (1.9) 226.9 147.4 261.2 (35.4) 316.9
Proof - - - - - - - -
Net income 1,110.1 504.1 1,614.2 1,208.4 80.8 1,289.2 1,726.1 244.4 1,970.5 2,116.8 (325.0) 1,791.8
Add: IPRD net income (from Earnings Release) 149.5 149.5 - - 297.3 297.3 315.9 315.9
Sum of above two rows of data 653.6 1,763.7 80.8 1,289.2 541.7 2,267.8 (9.1) 2,107.7
Reported on IR_workbook_Q4_2021 653.6 1,763.7 80.8 1,289.2 541.7 2,267.8 (9.1) 2,107.7
Proof - - - - - - 0.0 -
Earnings per share 1.22 0.56 1.78 1.33 0.09 1.41 1.90 0.26 2.16 2.32 (0.36) 1.96
Add: IPRD EPS (from Earnings Release) 0.16 0.16 - - 0.33 0.33 0.35 0.35
Sum of above two rows of data 0.72 1.94 0.09 1.41 0.59 2.49 (0.01) 2.31
Reported on IR_workbook_Q4_2021 0.72 1.94 0.09 1.41 0.59 2.49 (0.01) 2.31
Proof - - - - - - - -
*The company uses non-GAAP financial measures that differ from financial statements reported in conformity with U.S. generally accepted accounting principles (GAAP). The company's non-GAAP measures adjust reported results to exclude amortization of intangibles and items that are typically highly variable, difficult to predict, and/or of a size that could have a substantial impact on the company's reported operations for a period. The company believes that these non-GAAP measures provide useful information to investors. Among other things, they may help investors evaluate the company's ongoing operations. They can assist in making meaningful period-over-period comparisons and in identifying operating trends that would otherwise be masked or distorted by the items subject to the adjustments. Management uses these non-GAAP measures internally to evaluate the performance of the business, including to allocate resources and to evaluate results relative to incentive compensation targets. Investors should consider these non-GAAP measures in addition to, not as a substitute for or superior to, measures of financial performance prepared in accordance with GAAP. For additional information on the adjustments, refer to 'Significant Items'.
Note: Numbers may not add due to rounding.
Page 2 of 12 pages of financial data
Proof-YTD
LLY
Eli Lilly and Company
Reconciliation of GAAP Reported to Selected Non-GAAP Adjusted Information*
Investor Relations
Kevin Hern (317) 277-1838
Sara Smith (317) 690-1424
Kento Ueha (317) 651-3258
Lauren Zierke (317) 277-6524
Three Months Ended Three Months Ended Six Months Ended Six Months Ended
($ in millions, except per share data) March 31, 2021 March 31, 2020 June 30, 2021 June 30, 2020
GAAP Non-GAAP GAAP Non-GAAP GAAP Non-GAAP GAAP Non-GAAP
Reported Adjustments Adjusted Reported Adjustments Adjusted Reported Adjustments Adjusted Reported Adjustments Adjusted
Revenue $6,805.6 - $6,805.6 $5,859.8 - $5,859.8 $13,545.7 - $13,545.7 $11,359.2 - $11,359.2
Cost of sales 1,878.6 (207.2) 1,671.4 1,215.1 (58.6) 1,156.5 3,831.8 (762.4) 3,069.4 2,437.1 (161.4) 2,275.7
Research and development 1,684.8 - 1,684.8 1,392.1 - 1,392.1 3,357.6 - 3,357.6 2,782.3 - 2,782.3
Marketing, selling, and administrative 1,576.0 - 1,576.0 1,549.6 - 1,549.6 3,261.7 - 3,261.7 2,998.2 - 2,998.2
Operating expenses 3,260.8 - 3,260.8 2,941.7 - 2,941.7 6,619.3 - 6,619.3 5,780.5 - 5,780.5
Acquired in-process research and s/b 0 s/b 0 s/b 0 s/b 0
development 299.3 - 299.3 52.3 - 52.3 324.3 - 324.3 294.1 - 294.1
Asset impairment, restructuring,
and other special charges 211.6 (211.6) - 59.9 (59.9) - 211.6 (211.6) - 59.9 (59.9) -
Other - net, income (expense) 321.1 (286.5) 34.6 89.1 (161.7) (72.6) 511.6 (472.0) 39.6 536.0 (665.7) (129.7)
. .
Income taxes 121.1 22.1 143.2 223.4 (16.5) 206.9 324.8 98.5 423.3 455.1 (101.0) 354.1
Add: IPRD taxes (from Earnings Release) 62.9 62.9 11.0 11.0 68.1 68.1 25.1 25.1
Sum of above two rows of data 85.0 206.1 (5.5) 217.9 166.6 491.4 (75.9) 379.2
Reported on IR_workbook_Q4_2021 85.0 206.1 (5.5) 217.9 166.6 491.4 (75.9) 379.2
Proof - - - - - - - -
Net income 1,355.3 110.2 1,465.5 1,456.5 (26.7) 1,429.8 2,745.5 403.5 3,149.0 2,868.5 (343.4) 2,525.1
Add: IPRD net income (from Earnings Release) 236.4 236.4 41.3 41.3 256.2 256.2 269.0 269.0
Sum of above two rows of data 346.6 1,701.9 14.6 1,471.1 659.7 3,405.2 (74.4) 2,794.1
Reported on IR_workbook_Q4_2021 346.6 1,701.9 14.6 1,471.1 659.7 3,405.2 (74.4) 2,794.1
Proof - - - - - - - -
Earnings per share 1.49 0.12 1.61 1.60 (0.04) 1.56 3.01 0.45 3.46 3.15 (0.38) 2.77
Add: IPRD EPS (from Earnings Release) 0.26 0.26 0.05 0.05 0.28 0.28 0.30 0.30
Sum of above two rows of data 0.38 1.87 0.01 1.61 0.73 3.74 (0.08) 3.07
Reported on IR_workbook_Q4_2021 0.38 1.87 0.01 1.61 0.73 3.74 (0.08) 3.07
Proof - - - - - - - -
Nine Months Ended Nine Months Ended Twelve Months Ended Twelve Months Ended
September 30, 2021 September 30, 2020 December 31, 2021 December 31, 2020
GAAP Non-GAAP GAAP Non-GAAP GAAP Non-GAAP GAAP Non-GAAP
Reported Adjustments Adjusted Reported Adjustments Adjusted Reported Adjustments Adjusted Reported Adjustments Adjusted
Revenue $20,318.5 - $20,318.5 $17,099.8 - $17,099.8 $28,318.4 - $28,318.4 $24,539.8 - $24,539.8
Cost of sales 5,262.6 (771.4) 4,491.2 3,763.5 (287.9) 3,475.6 7,312.8 (908.8) 6,404.0 5,483.3 (415.2) 5,068.1
Research and development 5,066.5 - 5,066.5 4,247.7 - 4,247.7 7,025.9 - 7,025.9 6,085.7 - 6,085.7
Marketing, selling, and administrative 4,839.6 - 4,839.6 4,567.3 - 4,567.3 6,431.6 - 6,431.6 6,121.2 - 6,121.2
Operating expenses 9,906.1 - 9,906.1 8,815.0 - 8,815.0 13,457.5 - 13,457.5 12,206.9 - 12,206.9
Acquired in-process research and s/b 0 s/b 0 s/b 0 s/b 0
development 498.3 - 498.3 294.1 - 294.1 874.9 - 874.9 660.4 - 660.4
Asset impairment, restructuring,
and other special charges 211.6 (211.6) - 161.3 (161.3) - 316.1 (316.1) - 131.2 (131.2) -
Other - net, income (expense) (124.3) 156.6 32.3 694.9 (814.7) (119.8) (201.6) 227.2 25.6 1,171.9 (1,322.7) (150.8)
Income taxes 460.0 232.0 692.0 683.9 (102.8) 581.1 573.8 300.1 873.9 1,036.2 (188.7) 847.5
Add: IPRD taxes (from Earnings Release) 92.6 92.6 25.0 25.0 171.9 171.9 75.5 75.5
Sum of above two rows of data 324.6 784.6 (77.8) 606.1 472.0 1,045.8 (113.2) 923.0
Reported on IR_workbook_Q4_2021 324.6 784.6 (77.8) 606.1 472.0 1,045.8 (113.2) 923.0
Proof - - - - - - - -
Net income 3,855.6 907.6 4,763.2 4,076.9 (262.7) 3,814.2 5,581.7 1,152.0 6,733.7 6,193.7 (587.6) 5,606.1
Add: IPRD net income (from Earnings Release) 405.7 405.7 269.1 269.1 703.0 703.0 584.9 584.9
Sum of above two rows of data 1,313.3 5,168.9 6.4 4,083.3 1,855.0 7,436.7 (2.7) 6,191.0
Reported on IR_workbook_Q4_2021 1,313.3 5,168.9 6.4 4,083.3 1,855.0 7,436.7 (2.7) 6,191.0
Proof - - (0.0) - - - 0.0 -
Earnings per share 4.23 1.00 5.23
Joe Alterio: Joe Alterio: Increased by $0.01 since the otherwise calculated $5.22 would result in a $0.02 difference when adding the individual quarters across on the Significant Items and QTR Recon tabs ($1.61 +$1.85 +$1.78)
4.47 (0.29) 4.18 6.12 1.27 7.39 6.79 (0.65) 6.14
Add: IPRD EPS (from Earnings Release) 0.45 0.45 0.30 0.30 0.77 0.77 0.64 0.64
Sum of above two rows of data 1.45 5.68 0.01 4.48 2.04 8.16 (0.01) 6.78
Reported on IR_workbook_Q4_2021 1.44 5.67 0.01 4.48 2.04 8.16 (0.01) 6.78
Proof (0.01) (0.01) - - - - - -
Note: Numbers may not add due to rounding.

.99

Attachments

  • Original Link
  • Original Document
  • Permalink

Disclaimer

Eli Lilly and Company published this content on 20 April 2022 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 20 April 2022 13:44:03 UTC.