Item 5.02 Departure of Directors or Certain Officers; Election of Directors;


          Appointment of Certain Officers; Compensatory Arrangements of Certain
          Officers.

On March 11, 2021, Eloxx Pharmaceuticals, Inc. (the "Company") was advised by Mr. Stephen MacDonald of his intention to resign as the Company's Vice President, Finance and Accounting, and Treasurer (Principal Financial and Accounting Officer) effective March 26, 2021. Mr. MacDonald, who had been with the Company since October 2019, is resigning to pursue another business opportunity. The Company thanks Mr. MacDonald for his services and wishes him well in his new endeavor. The Company intends to appoint a successor to fill the role vacated by Mr. MacDonald prior to the resignation effective date.

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