Item 3.03 Material Modification to Rights of Security Holders.

As previously disclosed, on April 8, 2022, at the reconvened 2021 Annual Meeting of Shareholders (the "Annual Meeting") of the Company, the Company's shareholders approved several amendments to the Amended and Restated Certificate of Incorporation. The Amended and Restated Certificate of Incorporation became effective on May 2, 2022.

The Company's board of directors approved and adopted conforming amendments to the Amended and Restated By-laws, which became effective on May 2, 2022.

A description of the Amended and Restated Certificate of Incorporation and the general effect of the Amended and Restated Certificate of Incorporation and the Amended and Restated Bylaws upon the rights of the Company's shareholders are included in the Company's proxy statement, filed with the Securities and Exchange Commission on February 18, 2022, in the sections titled "PROPOSAL 1 - AMENDMENTS TO THE CERTIFICATE OF INCORPORATION", which is incorporated herein by reference.

Item 5.03 Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year

The disclosure set forth in Item 3.03 of this Report is incorporated into this Item 5.03 by reference.

Item 9.01. Financial Statements and Exhibits.





(d) Exhibits

The following exhibits are filed herewith:





3.1     Amended and Restated Certificate of Incorporation of Enzo Biochem, Inc.
3.2     Amended and Restated By-Laws of Enzo Biochem, Inc.
104   Cover Page Interactive Data File (embedded within the Inline XBRL document)




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