We will help eradicate cancer by preventing it, detecting it earlier, and guiding personalized treatment.

EXACT SCIENCES 1

Launching three new advanced cancer tests in 2025

Colon cancer screening

Molecular residual disease

Multi-cancer screening

$18B TAM $15B TAM $25B TAM

cologuard plusTM oncodetectTM cancerguardTM

launched March 2025 launched April 2025 launching 2H25

Source: Exact Sciences estimates, U.S. markets only;

Exact Sciences is preparing for the commercialization of Cancerguard

EXACT SCIENCES

EXACT SCIENCES 3



Exact Sciences is a global leader in advanced cancer diagnostics with a differentiated platform

OUR FOOTPRINT OUR IMPACT & SCALE OUR CAPABILITIES

7,000+

team members

~200K

ordering providers each quarter

9

R&D centers and labs

4.6M

test results in 2024

$2.76B

total revenue in 2024, up 10% Y/Y

$323M

adjusted EBITDA in 2024, up 48% YY

Proprietary scientific platform

detects cancer earlier and accurately

Powerful commercial engine, deep relationships, broad platform

Unrivaled ExactNexusTM tech platform enabling connectivity across healthcare

Please refer to the appendix accompanying this presentation for discussion of non-GAAP financial measures and reconciliations to GAAP financial measures.

The Exact Sciences platform enables sustainable revenue growth and profitability improvement over time


Grow revenue and profits







to fuel our mission

Invest in world-class talent dedicated to fighting

cancer



Offer tests that impact decision-making

Expand and leverage our platform

Generate rock-solid clinical evidence





Increase access & drive adoption

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EXACT Sciences Corporation published this content on May 15, 2025, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on May 16, 2025 at 12:55 UTC.