Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On March 20, 2023, James L.L. Tullis informed the Board of Directors (the "Board") of Exagen Inc. (the "Company") that he will resign from the Board effective at the Company's 2023 annual meeting of stockholders. Mr. Tullis' decision to resign was not due to a disagreement with the Board or the Company on any matter relating to the Company's operations, policies or practices.

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