GenScript Biotech Corporation is partnering with Allozymes, a Singapore-based biotech startup, to dramatically accelerate the enzyme discovery and development process. GenScript will provide the mutant libraries construction and expression, while Allozymes will provide ultra-high-throughput screening service for applications across various industries, including pharmaceuticals, cosmetics, and food and beverage. Naturally occurring enzymes and microbes are frequently used not only for biomedical purposes but also in the field of biotechnology.

The development of synthetic biology, through protein and metabolic engineering, has provided a solution to engineer custom microbes into cell factories that can massively produce not only the natural products but also a product with improved properties. This approach involves the generation of mutant libraries followed by a high- throughput screening technology.GenScript's strong expertise in de novo gene synthesis and its semiconductor-based oligo-synthesis technology provides the foundation for a Precision Mutant Library service that offers precise control over each synthesized variant. The result is a diverse and comprehensive mutant library with unbiased distribution.

Allozymes is a deep-tech company that is transforming ingredient manufacturing by unlocking the protein engineering potential through groundbreaking technologies. Allozymes offers directed evolution in the microfluidic system so that up to ten million variants can be screened per day at a fraction of the cost of other approaches. Using Allozymes technology, scientists can screen up to one million times more of the mutant library while reducing the cost of consumables and reagents.

The Allozymes approach increases the chance of success by 200 and reduces the timeline of screening to a day rather than years.