| | | | | | | |
 | REGENERON PHARMACEUTICALS, INC. | 0.61% | 2.42% | 4.69% | 30.47% | 106.55% | 71 235 |
| VERTEX PHARMACEUTICALS | 1.23% | 4.81% | 17.76% | 21.16% | 50.02% | 66 136 |
 | WUXI APPTEC CO., LTD. | 2.72% | -0.29% | -16.92% | -27.65% | 182.69% | 42 735 |
| BIONTECH SE | -2.90% | 2.62% | -36.77% | -16.70% | --.--% | 39 612 |
 | GENMAB A/S | 2.02% | 7.03% | -17.26% | -8.92% | 80.88% | 20 205 |
 | ARGENX SE | 2.11% | 2.45% | -3.17% | 38.71% | 161.84% | 17 597 |
| BEIGENE, LTD. | 4.29% | 3.35% | -49.32% | -60.49% | 5.86% | 14 168 |
| NEUROCRINE BIOSCIENCES, INC. | 0.95% | 2.45% | 1.19% | -10.20% | 8.01% | 8 237 |
| LEGEND BIOTECH CORPORATION | 2.63% | 8.26% | -8.58% | 6.93% | --.--% | 6 572 |
| SAREPTA THERAPEUTICS, INC. | 2.76% | 7.82% | -21.01% | -10.62% | -41.51% | 6 224 |
| HALOZYME THERAPEUTICS, INC. | 1.09% | 9.65% | 10.22% | 5.00% | 187.42% | 6 106 |
| EXELIXIS, INC. | 1.83% | -11.55% | -2.84% | -27.39% | -13.41% | 5 696 |
| INTRA-CELLULAR THERAPIES, INC. | 0.26% | -2.06% | 10.58% | 45.83% | 342.51% | 5 459 |
| ASCENDIS PHARMA A/S | 4.69% | 14.77% | -29.09% | -30.48% | -24.61% | 5 324 |
 | BIOCON LIMITED | -0.29% | 4.25% | -7.03% | -11.59% | 32.78% | 5 197 |
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