Item 7.01. Regulation FD Disclosure.

Ginkgo Bioworks Holdings, Inc. (the "Company") is aware of the closure of Silicon Valley Bank ("SVB") and appointment of the Federal Deposit Insurance Corporation as receiver. Only the cash balance of the Company's wholly-owned subsidiary Zymergen Inc. is held in deposit accounts at SVB, representing approximately $74 million or 6% of the Company's cash and cash equivalents as of December 31, 2022. The Company does not maintain any other material accounts or lines of credit with SVB.

The information in this Item 7.01 shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such filing.

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